|
rs1342326
|
|
|
0.840 |
GeneticVariation |
BEFREE |
C/C genotype of rs1342326 [OR (95% CI) 2.50 (1.33-4.69)] and A/A genotype of rs3939286 [OR (95% CI) 2.18 (1.05-4.52)] were associated with higher risk of asthma development.
|
31820077 |
2020 |
|
rs3939286
|
|
|
0.710 |
GeneticVariation |
BEFREE |
However, rs3939286 was more frequent in moderate and severe asthma.
|
31820077 |
2020 |
|
rs4921581
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Children wildtype for rs4921581 had increasing asthma risk with increasing hair cotinine level, whereas those carrying the <i>NAT1</i> minor allele had an increased risk of asthma regardless of cotinine level.
|
31809667 |
2019 |
|
rs1051730
|
|
|
0.020 |
GeneticVariation |
BEFREE |
After adjustment for age, smoking severity and genotype previously associated with heavy smoking (CHRNA3 rs1051730 AA), significant predictors of quitting were new diagnosis of ischemic heart disease/heart failure (OR=2.33, 95 % CI: 1.61-3.42), new diagnosis of asthma (OR=1.84, 95% CI: 1.18-2.90) and low number of pack-years.
|
31768164 |
2019 |
|
rs1544410
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In subgroup analyses by type of disease, we confirmed positive results for rs1544410 BsmI polymorphism in both asthma and atopic dermatitis, and for rs731236 TaqI polymorphism in atopic dermatitis.
|
31752548 |
2020 |
|
rs2228570
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Furthermore, we found that the rs2228570 genotype (OR, 3.763) of the VDR SNP and the vitamin D concentration (lower than 40 ng/ml, OR: 38.938) both contribute to increased susceptibility to bronchial asthma.
|
31719947 |
2019 |
|
rs2280090
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Haplotype analysis showed that rs2280090 and rs2280091 were associated with asthma in the patient group.
|
31719298 |
2019 |
|
rs2280091
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Haplotype analysis showed that rs2280090 and rs2280091 were associated with asthma in the patient group.
|
31719298 |
2019 |
|
rs1042713
|
|
|
0.100 |
GeneticVariation |
BEFREE |
For the rs1042713 polymorphism, no significant association with asthma risk was found in the overall population.
|
31699066 |
2019 |
|
rs1042714
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The meta-analysis suggests that the ADRB2 rs1042714 polymorphism has a protective association with asthma in the overall population and the pediatric subgroup.
|
31699066 |
2019 |
|
rs1042711
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Association of β2-adrenergic receptor gene polymorphisms (rs1042713, rs1042714, rs1042711) with asthma risk: a systematic review and updated meta-analysis.
|
31699066 |
2019 |
|
rs2228570
|
|
|
0.050 |
GeneticVariation |
BEFREE |
This meta-analysis was performed to identify whether VDR gene polymorphisms (FokI (rs2228570) or TaqI (rs731236) or BsmI (rs1544410) or ApaI (rs7975232)) play a role in the risk of asthma.
|
31654764 |
2020 |
|
rs7975232
|
|
|
0.040 |
GeneticVariation |
BEFREE |
This meta-analysis was performed to identify whether VDR gene polymorphisms (FokI (rs2228570) or TaqI (rs731236) or BsmI (rs1544410) or ApaI (rs7975232)) play a role in the risk of asthma.
|
31654764 |
2020 |
|
rs1544410
|
|
|
0.020 |
GeneticVariation |
BEFREE |
This meta-analysis was performed to identify whether VDR gene polymorphisms (FokI (rs2228570) or TaqI (rs731236) or BsmI (rs1544410) or ApaI (rs7975232)) play a role in the risk of asthma.
|
31654764 |
2020 |
|
rs731236
|
|
|
0.020 |
GeneticVariation |
BEFREE |
This meta-analysis was performed to identify whether VDR gene polymorphisms (FokI (rs2228570) or TaqI (rs731236) or BsmI (rs1544410) or ApaI (rs7975232)) play a role in the risk of asthma.
|
31654764 |
2020 |
|
rs678881
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Association intensity of the polymorphisms with the disease risk was assessed by odds ratio (OR) and 95% confidence interval (95%CI).The frequency of rs678881 GA genotype was obviously higher in cases than in controls (P = .03) and the carriage of this genotype conferred higher risk of asthma among children than GG genotype (OR = 2.03, 95%CI = 1.05-3.91).
|
31626088 |
2019 |
|
rs2280089
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Strong LD was found among rs678881, rs2280089 and rs2853209, and haplotype GGT was distinctly associated with the risk of asthma in children (OR = 0.28, 95%CI = 0.13-0.57).ADAM33 rs678881 polymorphism is significantly correlated with increased susceptibility to asthma in Chinese Han children.
|
31626088 |
2019 |
|
rs2853209
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Strong LD was found among rs678881, rs2280089 and rs2853209, and haplotype GGT was distinctly associated with the risk of asthma in children (OR = 0.28, 95%CI = 0.13-0.57).ADAM33 rs678881 polymorphism is significantly correlated with increased susceptibility to asthma in Chinese Han children.
|
31626088 |
2019 |
|
rs1837253
|
|
C |
0.840 |
GeneticVariation |
GWASCAT |
Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.
|
31619474 |
2019 |
|
rs992969
|
|
A |
0.810 |
GeneticVariation |
GWASCAT |
Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.
|
31619474 |
2019 |
|
rs1008723
|
|
G |
0.800 |
GeneticVariation |
GWASCAT |
Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.
|
31619474 |
2019 |
|
rs61816761
|
|
A |
0.780 |
GeneticVariation |
GWASCAT |
Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.
|
31619474 |
2019 |
|
rs146597587
|
|
G |
0.720 |
GeneticVariation |
GWASCAT |
Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.
|
31619474 |
2019 |
|
rs10021288
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.
|
31619474 |
2019 |
|
rs10056243
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.
|
31619474 |
2019 |