|
rs3768235
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A polymorphism in exon 3 (638G-->A) was seen in 4/42 (9.5%) MSI-positive endometrial cancers and 0/5 MSI-positive endometrial cancer cell lines.
|
11180594 |
2001 |
|
rs1056836
|
|
|
0.050 |
GeneticVariation |
BEFREE |
We evaluated the association between the CYP1B1 Leu432Val and CYP1B1 Asn453Ser polymorphisms and the COMT Val158Met polymorphism and invasive endometrial cancer risk in a case-control study nested within the Nurses' Health Study (n = 222 cases, 666 controls).
|
14656940 |
2004 |
|
rs1800440
|
|
|
0.050 |
GeneticVariation |
BEFREE |
We evaluated the association between the CYP1B1 Leu432Val and CYP1B1 Asn453Ser polymorphisms and the COMT Val158Met polymorphism and invasive endometrial cancer risk in a case-control study nested within the Nurses' Health Study (n = 222 cases, 666 controls).
|
14656940 |
2004 |
|
rs4680
|
|
|
0.040 |
GeneticVariation |
BEFREE |
We evaluated the association between the CYP1B1 Leu432Val and CYP1B1 Asn453Ser polymorphisms and the COMT Val158Met polymorphism and invasive endometrial cancer risk in a case-control study nested within the Nurses' Health Study (n = 222 cases, 666 controls).
|
14656940 |
2004 |
|
rs605059
|
|
|
0.030 |
GeneticVariation |
BEFREE |
We identified and genotyped two haplotype-tagging SNPs (+1004C/T and +1322C/A), and genotyped an additional SNP [+1954A/G (Ser312Gly)] in nested case-control studies of endometrial cancer (cases = 222, controls = 666) and breast cancer (cases = 1007, controls = 1441) in the prospective Nurses' Health Study.
|
14973105 |
2004 |
|
rs1057520001
|
|
|
0.010 |
GeneticVariation |
BEFREE |
An association between endometrial cancer and the polymorphism at codon 31 (AGC/serine to AGA/arginine [Ser(31)Arg]) of the p21 gene, which is known to be a downstream mediator of p53, has also been reported.
|
15099969 |
2004 |
|
rs886039484
|
|
|
0.010 |
GeneticVariation |
BEFREE |
An association between endometrial cancer and the polymorphism at codon 31 (AGC/serine to AGA/arginine [Ser(31)Arg]) of the p21 gene, which is known to be a downstream mediator of p53, has also been reported.
|
15099969 |
2004 |
|
rs1256049
|
|
|
0.010 |
GeneticVariation |
BEFREE |
After adjusting for potential confounders, we observed no association between ESR2 gene polymorphisms and endometrial cancer risk [rs1256049 (OR = 1.2; 95%CI: 0.7-2.3), rs1271572 (OR = 0.8; 95%CI: 0.5-1.1) and CA repeat (22 repeat allele versus > or = 22 repeat allele, OR = 1.1; 95%CI: 0.7-1.7)].
|
15280642 |
2004 |
|
rs1271572
|
|
|
0.010 |
GeneticVariation |
BEFREE |
After adjusting for potential confounders, we observed no association between ESR2 gene polymorphisms and endometrial cancer risk [rs1256049 (OR = 1.2; 95%CI: 0.7-2.3), rs1271572 (OR = 0.8; 95%CI: 0.5-1.1) and CA repeat (22 repeat allele versus > or = 22 repeat allele, OR = 1.1; 95%CI: 0.7-1.7)].
|
15280642 |
2004 |
|
rs1801282
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No evidence of a role for PPARgamma Pro12Ala polymorphism in endometrial cancer susceptibility.
|
15608564 |
2004 |
|
rs1805192
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No evidence of a role for PPARgamma Pro12Ala polymorphism in endometrial cancer susceptibility.
|
15608564 |
2004 |
|
rs1042522
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Association of p73 G4C14-to-A4T14 polymorphism at exon 2 and p53 Arg72Pro polymorphism with the risk of endometrial cancer in Japanese subjects.
|
15723718 |
2005 |
|
rs1131691014
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Association of p73 G4C14-to-A4T14 polymorphism at exon 2 and p53 Arg72Pro polymorphism with the risk of endometrial cancer in Japanese subjects.
|
15723718 |
2005 |
|
rs878854066
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Association of p73 G4C14-to-A4T14 polymorphism at exon 2 and p53 Arg72Pro polymorphism with the risk of endometrial cancer in Japanese subjects.
|
15723718 |
2005 |
|
rs4994
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The prevalence of the Arg allele of the Trp64Arg polymorphism in the beta3-adrenergic receptor gene may contribute to the susceptibility to endometrial cancer among obese/overweight individuals.
|
15743038 |
2004 |
|
rs1695
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our findings suggested that the GSTP1 Ile(105)Val polymorphism was associated with an increased risk of endometrial cancer.
|
15837751 |
2005 |
|
rs28930073
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genetic testing for the MLH1 D132H allele exclusively is therefore unlikely to be cost effective for genetic risk assessment in American population-based and clinic-based colorectal cancer and endometrial cancer patients.
|
15991064 |
2005 |
|
rs1800562
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In patients with breast, ovarian, and endometrial cancer, C282Y frequencies were also low (1.0, 1.3, and 3.8%, respectively), and no cancer risk associated with the C282Y mutation was found.
|
16216474 |
2006 |
|
rs759843019
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Carriage of at least one variant allele for XPA G23A was associated with decreased risk of endometrial cancer [odds ratio (OR), 0.70; 95% confidence interval (95% CI), 0.53-0.93].
|
16284373 |
2005 |
|
rs997050266
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Carriage of at least one variant allele for XPA G23A was associated with decreased risk of endometrial cancer [odds ratio (OR), 0.70; 95% confidence interval (95% CI), 0.53-0.93].
|
16284373 |
2005 |
|
rs397517202
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Mutational analysis of previously unexamined tumors showed an amino acid change from threonine to alanine (T1025A) in exon 20 in one of 28 endometrial cancer samples and 6 endometrial cell lines.
|
16764926 |
2007 |
|
rs12917
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We assessed the two functional polymorphisms, the Leu84Phe and Ile143Val, in relation to endometrial cancer risk in a nested case-control study within the Nurses' Health Study (cases = 456, controls = 1134).
|
16777993 |
2006 |
|
rs2308321
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We did not observe an association between the Ile143Val polymorphism and e</span>ndometrial cancer risk overall.
|
16777993 |
2006 |
|
rs4987886
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results indicated an increased risk of developing endometroid endometrial cancer for homozygous carriers of the rare allele (AA) of a tagSNP (rs4987886) in CHEK2 (P = 0.005) when contrasted with GG carriers.
|
17164260 |
2007 |
|
rs1045642
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our observation suggests that MDR1 C3435T polymorphism is correlated with endometrial cancer susceptibility.
|
17300681 |
2007 |