rs3768235
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A polymorphism in exon 3 (638G-->A) was seen in 4/42 (9.5%) MSI-positive endometrial cancers and 0/5 MSI-positive endometrial cancer cell lines.
|
11180594 |
2001 |
rs1056836
|
|
|
0.050 |
GeneticVariation |
BEFREE |
We evaluated the association between the CYP1B1 Leu432Val and CYP1B1 Asn453Ser polymorphisms and the COMT Val158Met polymorphism and invasive endometrial cancer risk in a case-control study nested within the Nurses' Health Study (n = 222 cases, 666 controls).
|
14656940 |
2004 |
rs1800440
|
|
|
0.050 |
GeneticVariation |
BEFREE |
We evaluated the association between the CYP1B1 Leu432Val and CYP1B1 Asn453Ser polymorphisms and the COMT Val158Met polymorphism and invasive endometrial cancer risk in a case-control study nested within the Nurses' Health Study (n = 222 cases, 666 controls).
|
14656940 |
2004 |
rs4680
|
|
|
0.040 |
GeneticVariation |
BEFREE |
We evaluated the association between the CYP1B1 Leu432Val and CYP1B1 Asn453Ser polymorphisms and the COMT Val158Met polymorphism and invasive endometrial cancer risk in a case-control study nested within the Nurses' Health Study (n = 222 cases, 666 controls).
|
14656940 |
2004 |
rs605059
|
|
|
0.030 |
GeneticVariation |
BEFREE |
We identified and genotyped two haplotype-tagging SNPs (+1004C/T and +1322C/A), and genotyped an additional SNP [+1954A/G (Ser312Gly)] in nested case-control studies of endometrial cancer (cases = 222, controls = 666) and breast cancer (cases = 1007, controls = 1441) in the prospective Nurses' Health Study.
|
14973105 |
2004 |
rs1057520001
|
|
|
0.010 |
GeneticVariation |
BEFREE |
An association between endometrial cancer and the polymorphism at codon 31 (AGC/serine to AGA/arginine [Ser(31)Arg]) of the p21 gene, which is known to be a downstream mediator of p53, has also been reported.
|
15099969 |
2004 |
rs1256049
|
|
|
0.010 |
GeneticVariation |
BEFREE |
After adjusting for potential confounders, we observed no association between ESR2 gene polymorphisms and endometrial cancer risk [rs1256049 (OR = 1.2; 95%CI: 0.7-2.3), rs1271572 (OR = 0.8; 95%CI: 0.5-1.1) and CA repeat (22 repeat allele versus > or = 22 repeat allele, OR = 1.1; 95%CI: 0.7-1.7)].
|
15280642 |
2004 |
rs1271572
|
|
|
0.010 |
GeneticVariation |
BEFREE |
After adjusting for potential confounders, we observed no association between ESR2 gene polymorphisms and endometrial cancer risk [rs1256049 (OR = 1.2; 95%CI: 0.7-2.3), rs1271572 (OR = 0.8; 95%CI: 0.5-1.1) and CA repeat (22 repeat allele versus > or = 22 repeat allele, OR = 1.1; 95%CI: 0.7-1.7)].
|
15280642 |
2004 |
rs1801282
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No evidence of a role for PPARgamma Pro12Ala polymorphism in endometrial cancer susceptibility.
|
15608564 |
2004 |
rs1805192
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No evidence of a role for PPARgamma Pro12Ala polymorphism in endometrial cancer susceptibility.
|
15608564 |
2004 |
rs4994
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The prevalence of the Arg allele of the Trp64Arg polymorphism in the beta3-adrenergic receptor gene may contribute to the susceptibility to endometrial cancer among obese/overweight individuals.
|
15743038 |
2004 |
rs886039484
|
|
|
0.010 |
GeneticVariation |
BEFREE |
An association between endometrial cancer and the polymorphism at codon 31 (AGC/serine to AGA/arginine [Ser(31)Arg]) of the p21 gene, which is known to be a downstream mediator of p53, has also been reported.
|
15099969 |
2004 |
rs1042522
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Association of p73 G4C14-to-A4T14 polymorphism at exon 2 and p53 Arg72Pro polymorphism with the risk of endometrial cancer in Japanese subjects.
|
15723718 |
2005 |
rs1131691014
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Association of p73 G4C14-to-A4T14 polymorphism at exon 2 and p53 Arg72Pro polymorphism with the risk of endometrial cancer in Japanese subjects.
|
15723718 |
2005 |
rs878854066
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Association of p73 G4C14-to-A4T14 polymorphism at exon 2 and p53 Arg72Pro polymorphism with the risk of endometrial cancer in Japanese subjects.
|
15723718 |
2005 |
rs1695
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our findings suggested that the GSTP1 Ile(105)Val polymorphism was associated with an increased risk of endometrial cancer.
|
15837751 |
2005 |
rs28930073
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genetic testing for the MLH1 D132H allele exclusively is therefore unlikely to be cost effective for genetic risk assessment in American population-based and clinic-based colorectal cancer and endometrial cancer patients.
|
15991064 |
2005 |
rs759843019
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Carriage of at least one variant allele for XPA G23A was associated with decreased risk of endometrial cancer [odds ratio (OR), 0.70; 95% confidence interval (95% CI), 0.53-0.93].
|
16284373 |
2005 |
rs997050266
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Carriage of at least one variant allele for XPA G23A was associated with decreased risk of endometrial cancer [odds ratio (OR), 0.70; 95% confidence interval (95% CI), 0.53-0.93].
|
16284373 |
2005 |
rs12917
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We assessed the two functional polymorphisms, the Leu84Phe and Ile143Val, in relation to endometrial cancer risk in a nested case-control study within the Nurses' Health Study (cases = 456, controls = 1134).
|
16777993 |
2006 |
rs1800562
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In patients with breast, ovarian, and endometrial cancer, C282Y frequencies were also low (1.0, 1.3, and 3.8%, respectively), and no cancer risk associated with the C282Y mutation was found.
|
16216474 |
2006 |
rs2308321
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We did not observe an association between the Ile143Val polymorphism and e</span>ndometrial cancer risk overall.
|
16777993 |
2006 |
rs1048943
|
|
|
0.030 |
GeneticVariation |
BEFREE |
We did not observe any statistically significant associations between the MspI, Thr461Asn or Ile462Val polymorphisms and endometrial cancer risk or any significant effect modification by cigarette-smoking status.
|
17717632 |
2007 |
rs605059
|
|
|
0.030 |
GeneticVariation |
BEFREE |
We also found that among premenopausal women soy isoflavone intake significantly interacted with the rs605059 genotype in relation to endometrial cancer and that the inverse association between soy isoflavone intake and endometrial cancer only appeared among those with at least one A allele of the rs605059 polymorphism.
|
17301695 |
2007 |
rs1217691063
|
|
|
0.020 |
GeneticVariation |
BEFREE |
No association was observed between endometrial cancer and the MTHFR 677C>T, 1298 A>C, and 1793G>A polymorphisms or derived haplotypes.
|
17301261 |
2007 |