rs121913487
|
|
C |
0.800 |
CausalMutation |
CLINVAR |
FLT3 inhibition selectively kills childhood acute lymphoblastic leukemia cells with high levels of FLT3 expression.
|
15374878 |
2005 |
rs121913487
|
|
C |
0.800 |
CausalMutation |
CLINVAR |
Variable sensitivity of FLT3 activation loop mutations to the small molecule tyrosine kinase inhibitor MLN518.
|
15256420 |
2004 |
rs121913487
|
|
T |
0.800 |
CausalMutation |
CLINVAR |
Variable sensitivity of FLT3 activation loop mutations to the small molecule tyrosine kinase inhibitor MLN518.
|
15256420 |
2004 |
rs121913487
|
|
T |
0.800 |
CausalMutation |
CLINVAR |
Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies.
|
11290608 |
2001 |
rs121913487
|
|
C |
0.800 |
CausalMutation |
CLINVAR |
Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies.
|
11290608 |
2001 |
rs121913488
|
|
A |
0.740 |
CausalMutation |
CLINVAR |
Prospective enterprise-level molecular genotyping of a cohort of cancer patients.
|
25157968 |
2014 |
rs121913488
|
|
G |
0.740 |
CausalMutation |
CLINVAR |
Prospective enterprise-level molecular genotyping of a cohort of cancer patients.
|
25157968 |
2014 |
rs121913488
|
|
T |
0.740 |
CausalMutation |
CLINVAR |
The importance of relative mutant level for evaluating impact on outcome of KIT, FLT3 and CBL mutations in core-binding factor acute myeloid leukemia.
|
23783394 |
2013 |
rs121913488
|
|
T |
0.740 |
CausalMutation |
CLINVAR |
The role of kinase inhibitors in the treatment of patients with acute myeloid leukemia.
|
23714533 |
2013 |
rs121913488
|
|
A |
0.740 |
CausalMutation |
CLINVAR |
Mutational landscape of AML with normal cytogenetics: biological and clinical implications.
|
23261068 |
2013 |
rs121913488
|
|
T |
0.740 |
CausalMutation |
CLINVAR |
Prospective evaluation of gene mutations and minimal residual disease in patients with core binding factor acute myeloid leukemia.
|
23321257 |
2013 |
rs121913488
|
|
G |
0.740 |
CausalMutation |
CLINVAR |
The importance of relative mutant level for evaluating impact on outcome of KIT, FLT3 and CBL mutations in core-binding factor acute myeloid leukemia.
|
23783394 |
2013 |
rs121913488
|
|
T |
0.740 |
CausalMutation |
CLINVAR |
Mutational landscape of AML with normal cytogenetics: biological and clinical implications.
|
23261068 |
2013 |
rs121913488
|
|
G |
0.740 |
CausalMutation |
CLINVAR |
Prospective evaluation of gene mutations and minimal residual disease in patients with core binding factor acute myeloid leukemia.
|
23321257 |
2013 |
rs121913488
|
|
A |
0.740 |
CausalMutation |
CLINVAR |
The importance of relative mutant level for evaluating impact on outcome of KIT, FLT3 and CBL mutations in core-binding factor acute myeloid leukemia.
|
23783394 |
2013 |
rs121913488
|
|
G |
0.740 |
CausalMutation |
CLINVAR |
In addition, crenolanib inhibited drug-resistant AML primary blasts with FLT3-ITD and D835H/Y mutations.
|
24046014 |
2013 |
rs121913488
|
|
G |
0.740 |
CausalMutation |
CLINVAR |
The role of kinase inhibitors in the treatment of patients with acute myeloid leukemia.
|
23714533 |
2013 |
rs121913488
|
|
A |
0.740 |
CausalMutation |
CLINVAR |
Activity of ponatinib against clinically-relevant AC220-resistant kinase domain mutants of FLT3-ITD.
|
23430109 |
2013 |
rs121913488
|
|
G |
0.740 |
CausalMutation |
CLINVAR |
Activity of ponatinib against clinically-relevant AC220-resistant kinase domain mutants of FLT3-ITD.
|
23430109 |
2013 |
rs121913488
|
|
A |
0.740 |
CausalMutation |
CLINVAR |
The role of kinase inhibitors in the treatment of patients with acute myeloid leukemia.
|
23714533 |
2013 |
rs121913488
|
|
A |
0.740 |
CausalMutation |
CLINVAR |
Prospective evaluation of gene mutations and minimal residual disease in patients with core binding factor acute myeloid leukemia.
|
23321257 |
2013 |
rs121913488
|
|
T |
0.740 |
CausalMutation |
CLINVAR |
Activity of ponatinib against clinically-relevant AC220-resistant kinase domain mutants of FLT3-ITD.
|
23430109 |
2013 |
rs121913488
|
|
G |
0.740 |
CausalMutation |
CLINVAR |
Mutational landscape of AML with normal cytogenetics: biological and clinical implications.
|
23261068 |
2013 |
rs121913488
|
|
A |
0.740 |
CausalMutation |
CLINVAR |
Sorafenib treatment of FLT3-ITD(+) acute myeloid leukemia: favorable initial outcome and mechanisms of subsequent nonresponsiveness associated with the emergence of a D835 mutation.
|
22368270 |
2012 |
rs121913488
|
|
T |
0.740 |
CausalMutation |
CLINVAR |
Sorafenib treatment of FLT3-ITD(+) acute myeloid leukemia: favorable initial outcome and mechanisms of subsequent nonresponsiveness associated with the emergence of a D835 mutation.
|
22368270 |
2012 |