rs4664308
|
|
|
0.010 |
GeneticVariation |
BEFREE |
PLA2R1 displayed a nominally significantly genetic association with SLE [for rs4664308, P = 0.02, odds ratio (OR) 1.16, 95 % confidence interval (CI) 1.02-1.31; for rs3792192, P = 7.9 × 10(-3), OR 1.18, 95 % CI 1.05-1.34] and LN (for rs4664308, P = 0.04).
|
26645973 |
2016 |
rs117026326
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Patients carrying genotype TT of rs117026326 had lower 24-hour urinary total protein (24 hours UTP, g/24 hours), 24-hour urinary protein level (g/L·24 hours), lower frequency of the proteinuria and lupus nephritis (LN).
|
31374066 |
2019 |
rs7708392
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Our results suggested that TNIP1 SNP (rs7708392) might be associated with the LN</span> in Egyptian SLE patients.
|
29589214 |
2018 |
rs1456896
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results suggest that the rs1456896 A allele is associated with protective susceptibility to LN.
|
27684961 |
2017 |
rs1143679
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Our meta-analyses confirm that the ITGAM rs1143679 polymorphism is associated with SLE susceptibility in different ethnic groups and demonstrate that the polymorphism is associated with LN in European.
|
25315704 |
2015 |
rs1635564
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Notably, gene dose effects of the rs1635564 variant allele were observed for SLE (p = 0.005) and LN (p = 0.01).
|
30269634 |
2019 |
rs5744168
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No allelic nor genotype association was found with TLR-5-rs5744168 in SLE. but the T allele and the TT genotype were raised significantly in the LN group (P < 0·05).
|
28763101 |
2017 |
rs2157257
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Multiple peaks of association exceeding a Bonferroni corrected P-value of P < 2.03 × 10(-3) were observed between LN and MYH9 in EAs (N = 4620), with the most pronounced association at rs2157257 (P = 4.7 × 10(-4), odds ratio (OR) = 1.205).
|
22189356 |
2012 |
rs6897932
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Moreover, association studies were also performed contraposing the relationship between the SNP rs6897932 C/T and lupus nephritis as well as 10 clinical features of SLE; however, no significant association signal was found regarding the distribution of allele and genotype frequencies between SLE patients positive and negative for the presence of 11 sub-phenotypes.
|
24242875 |
2014 |
rs1364989
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Lupus nephritis susceptibility loci in women with systemic lupus erythematosus.
|
24925725 |
2014 |
rs2647012
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Lupus nephritis susceptibility loci in women with systemic lupus erythematosus.
|
24925725 |
2014 |
rs274068
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Lupus nephritis susceptibility loci in women with systemic lupus erythematosus.
|
24925725 |
2014 |
rs601162
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Lupus nephritis susceptibility loci in women with systemic lupus erythematosus.
|
24925725 |
2014 |
rs7773456
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Lupus nephritis susceptibility loci in women with systemic lupus erythematosus.
|
24925725 |
2014 |
rs7834765
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Lupus nephritis susceptibility loci in women with systemic lupus erythematosus.
|
24925725 |
2014 |
rs8012283
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Lupus nephritis susceptibility loci in women with systemic lupus erythematosus.
|
24925725 |
2014 |
rs329498
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Likewise, the rs329498 SNP was also associated with the clinical features LN and malar rash in SLE patients.
|
27018966 |
2016 |
rs3743930
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In this regard, absence of the E148Q mutation in SLE</span> nephritis may serve as a clue for further investigation into its role as a general modulatory polymorphism for inflammation.
|
25413357 |
2015 |
rs11889341
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the case-control analysis of cohort I, four highly linked SNPs in STAT4 were associated with lupus nephritis with genome wide significance with p = 3.7 × 10(-9), OR 2.20 for the best SNP rs11889341.
|
24386384 |
2013 |
rs2397084
|
|
|
0.010 |
GeneticVariation |
BEFREE |
IL-17A rs2275913, IL-17F rs763780 and rs2397084 are not related to the LN development, SLE disease activity or overall survival.
|
26515887 |
2016 |
rs763780
|
|
|
0.010 |
GeneticVariation |
BEFREE |
IL-17A rs2275913, IL-17F rs763780 and rs2397084 are not related to the LN development, SLE disease activity or overall survival.
|
26515887 |
2016 |
rs2275913
|
|
|
0.010 |
GeneticVariation |
BEFREE |
IL-17A rs2275913, IL-17F rs763780 and rs2397084 are not related to the LN development, SLE disease activity or overall survival.
|
26515887 |
2016 |
rs1799964
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here, we aimed to examine whether the TNF -238G/A, -308G/A, -376G/A (rs1800750), and -1031T/C (rs1799964) polymorphisms confer SLE or lupus nephritis (LN) susceptibility in a Mexican population.
|
29611038 |
2018 |
rs7848647
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genotypes distribution of rs6478109, rs7848647 were strongly related to lupus nephritis within SLE (p = 0.004, p = 0.011), respectively.
|
31081141 |
2019 |
rs6478109
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genotypes distribution of rs6478109, rs7848647 were strongly related to lupus nephritis within SLE (p = 0.004, p = 0.011), respectively.
|
31081141 |
2019 |