Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs11012732
rs11012732
A 0.810 GeneticVariation GWASDB We identified a new susceptibility locus for meningioma at 10p12.31 (MLLT10, rs11012732, odds ratio = 1.46, P(combined) = 1.88 × 10(-14)). 21804547

2011

dbSNP: rs11012732
rs11012732
A 0.810 GeneticVariation GWASCAT We identified a new susceptibility locus for meningioma at 10p12.31 (MLLT10, rs11012732, odds ratio = 1.46, P(combined) = 1.88 × 10(-14)). 21804547

2011

dbSNP: rs11012732
rs11012732
0.810 GeneticVariation BEFREE We identified a new susceptibility locus for meningioma at 10p12.31 (MLLT10, rs11012732, odds ratio = 1.46, P(combined) = 1.88 × 10(-14)). 21804547

2011

dbSNP: rs2686876
rs2686876
0.710 GeneticVariation BEFREE We identified a new susceptibility locus for meningioma at 11p15.5 (rs2686876, odds ratio = 1.44, P = 9.86 × 10-9). 29762745

2018

dbSNP: rs2686876
rs2686876
T 0.710 GeneticVariation GWASCAT We identified a new susceptibility locus for meningioma at 11p15.5 (rs2686876, odds ratio = 1.44, P = 9.86 × 10-9). 29762745

2018

dbSNP: rs1568234664
rs1568234664
A 0.700 GeneticVariation CLINVAR

dbSNP: rs1045485
rs1045485
0.020 GeneticVariation BEFREE The CASP8 D302H polymorphism genotypic frequencies were not statistically significantly different between meningioma cases and controls, with frequencies of GG, GC and CC genotypes of 71.2%, 19,2% and 9.6%; and 57.9%, 36.8% and 5.3%, respectively. 26359420

2016

dbSNP: rs1045485
rs1045485
0.020 GeneticVariation BEFREE We tested the hypothesis that the CASP8 polymorphism D302H may influence risk of meningioma through analysis of five independent series of case patients and controls (n=631 and 637, respectively). 18823701

2009

dbSNP: rs121434592
rs121434592
0.020 GeneticVariation BEFREE Mutations in <i>NF2, TRAF7, SMO, KLF4</i>, and <i>AKT1</i> E17K did not predict RB1 S780 staining or progression in grade 1.5 meningiomas. 31615938

2020

dbSNP: rs121434592
rs121434592
0.020 GeneticVariation BEFREE A subset of meningiomas lacking NF2 alterations harbored recurrent oncogenic mutations in AKT1 (p.Glu17Lys) and SMO (p.Trp535Leu) and exhibited immunohistochemical evidence of activation of these pathways. 23334667

2013

dbSNP: rs1217691063
rs1217691063
0.020 GeneticVariation BEFREE The current meta-analysis firstly provides evidence that the MTHFR C677T polymorphism may modify the risk for brain tumors, particularly meningioma. 23846816

2013

dbSNP: rs1217691063
rs1217691063
0.020 GeneticVariation BEFREE C677T gene polymorphism of methylenetetrahydrofolate reductase (MTHFR) in meningiomas and high-grade gliomas. 16821630

2006

dbSNP: rs12770228
rs12770228
0.020 GeneticVariation BEFREE Our updated meta-analysis provided statistical evidence for the role of <i>MLLT10</i> rs12770228, <i>MTRR</i> rs1801394, and <i>MTHFR</i> rs1801131 in increased susceptibility to meningioma. 28405167

2017

dbSNP: rs12770228
rs12770228
0.020 GeneticVariation BEFREE The variant 'A' allele in MLLT10 rs12770228 was associated with an increased risk of meningioma (per allele odds ratio: 1.25; 95% confidence interval: 1.02, 1.53; P=0.031). 24755950

2015

dbSNP: rs1801131
rs1801131
0.020 GeneticVariation BEFREE Our updated meta-analysis provided statistical evidence for the role of <i>MLLT10</i> rs12770228, <i>MTRR</i> rs1801394, and <i>MTHFR</i> rs1801131 in increased susceptibility to meningioma. 28405167

2017

dbSNP: rs1801131
rs1801131
0.020 GeneticVariation BEFREE In conclusion, our meta-analysis suggests that two folate metabolism genetic variants MTRR A66G (rs1801394) and MTHFR A1298C (rs1801131) contribute to genetic susceptibility to meningioma and glioma in adults. 28915669

2017

dbSNP: rs1801394
rs1801394
0.020 GeneticVariation BEFREE Moreover, we found that MTRR A66G (rs1801394) variant genotypes was associated with increased risk of meni</span>ngioma and glioma (G vs. A: OR=1.11, P=0.020; GG vs. AA+AG: OR=1.17, P=0.043; GG vs. AA: OR=1.22, P=0.023). 28915669

2017

dbSNP: rs1801394
rs1801394
0.020 GeneticVariation BEFREE Our updated meta-analysis provided statistical evidence for the role of <i>MLLT10</i> rs12770228, <i>MTRR</i> rs1801394, and <i>MTHFR</i> rs1801131 in increased susceptibility to meningioma. 28405167

2017

dbSNP: rs4968451
rs4968451
0.020 GeneticVariation BEFREE The polymorphisms rs4968451T>G in BRIP1 were significantly associated with the risk of meningioma (TT vs. TG vs. GG additive, P = 0.005; TT+TG vs. GG dominant, P = 0.015; TT/GT+GG recessive, P = 0.034). 29581016

2018

dbSNP: rs4968451
rs4968451
0.020 GeneticVariation BEFREE We have identified a novel association between rs4968451 and meningioma risk. 18270339

2008

dbSNP: rs1035938
rs1035938
0.010 GeneticVariation BEFREE We observed significantly increased risk of meningioma with the T variant of GLTSCR1 rs1035938 (OR(CT/TT) = 3.5; 95% confidence interval: 1.8-6.9; P(trend) .0006), which persisted after controlling for multiple comparisons (P = .019). 20150366

2010

dbSNP: rs1056836
rs1056836
0.010 GeneticVariation BEFREE The CYP1B1 V432L homozygous variant was associated with decreased risk of meningioma (odds ratio [OR] = 0.6; 95% CI, 0.3-1.0) but not the other tumor types. 16598069

2006

dbSNP: rs10936599
rs10936599
0.010 GeneticVariation BEFREE Three out of the eight evaluated LTL SNPs were significantly associated with increased meningioma risk (rs10936599: OR 1.14, 95% CI 1.01-1.28, rs2736100: OR 1.13, 95% CI 1.03-1.25, rs9420907: OR 1.22, 95% CI 1.07-1.39). 30796745

2019

dbSNP: rs113488022
rs113488022
0.010 GeneticVariation BEFREE Our data suggest routine screening for BRAF V600E mutations for glioblastomas WHO grade IV below the age of 30, especially in glioblastomas with epithelioid features and in all rhabdoid meningiomas WHO grade III. 27350555

2016

dbSNP: rs121913377
rs121913377
0.010 GeneticVariation BEFREE Our data suggest routine screening for BRAF V600E mutations for glioblastomas WHO grade IV below the age of 30, especially in glioblastomas with epithelioid features and in all rhabdoid meningiomas WHO grade III. 27350555

2016