|
rs121434259
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs1568234664
|
|
A |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
|
rs587776563
|
|
G |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs1329443726
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two anaplastic meningiomas carried somatic point mutations in CDKN2A (c.262G>T: E88X and c.262G>A: E88K) and p14(ARF) (c.305G>T: G102V and c.305G>A: G102E).
|
11485924 |
2001 |
|
rs1475218156
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two anaplastic meningiomas carried somatic point mutations in CDKN2A (c.262G>T: E88X and c.262G>A: E88K) and p14(ARF) (c.305G>T: G102V and c.305G>A: G102E).
|
11485924 |
2001 |
|
rs768803947
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A tumor-specific missense mutation as a result of an A-to-G transition with an Asn204Ser change was found in one meningioma that nevertheless retained the normal allele.
|
11520574 |
2001 |
|
rs1056836
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The CYP1B1 V432L homozygous variant was associated with decreased risk of meningioma (odds ratio [OR] = 0.6; 95% CI, 0.3-1.0) but not the other tumor types.
|
16598069 |
2006 |
|
rs1217691063
|
|
|
0.020 |
GeneticVariation |
BEFREE |
C677T gene polymorphism of methylenetetrahydrofolate reductase (MTHFR) in meningiomas and high-grade gliomas.
|
16821630 |
2006 |
|
rs730882035
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We describe a Sicilian girl with type 2C VHL who showed the apparently de novo mutation R161Q in association with an extra-axial supratentorial frontal meningioma, which can be included as a characteristic sign in VHL.
|
17102087 |
2006 |
|
rs4968451
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We have identified a novel association between rs4968451 and meningioma risk.
|
18270339 |
2008 |
|
rs699473
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We observed increased risk of glioma (odds ratio [OR](CT/CC)=1.3; 95% confidence interval [95% CI], 1.0-1.7) and meningioma (OR(CT/CC)=1.7; 95% CI, 1.1-2.7) with the C variant of SOD3 rs699473.
|
18682580 |
2008 |
|
rs1045485
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We tested the hypothesis that the CASP8 polymorphism D302H may influence risk of meningioma through analysis of five independent series of case patients and controls (n=631 and 637, respectively).
|
18823701 |
2009 |
|
rs7574920
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Furthermore, the same GPX1 polymorphisms and XDH rs7574920 were found to significantly modify the association between cumulative lead exposure and meningioma.
|
19505917 |
2009 |
|
rs1035938
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We observed significantly increased risk of meningioma with the T variant of GLTSCR1 rs1035938 (OR(CT/TT) = 3.5; 95% confidence interval: 1.8-6.9; P(trend) .0006), which persisted after controlling for multiple comparisons (P = .019).
|
20150366 |
2010 |
|
rs1800067
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Significantly increased meningioma risk was also observed for the minor allele variants of ERCC4 rs1800067 (P(trend) .01); MUTYH rs3219466 (P(trend) .02), and PCNA rs25406 (P(trend) .03).
|
20150366 |
2010 |
|
rs1805794
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The NBN rs1805794 minor allele variant was associated with decreased meningioma risk (P(trend) .006).
|
20150366 |
2010 |
|
rs25406
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Significantly increased meningioma risk was also observed for the minor allele variants of ERCC4 rs1800067 (P(trend) .01); MUTYH rs3219466 (P(trend) .02), and PCNA rs25406 (P(trend) .03).
|
20150366 |
2010 |
|
rs3219466
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Significantly increased meningioma risk was also observed for the minor allele variants of ERCC4 rs1800067 (P(trend) .01); MUTYH rs3219466 (P(trend) .02), and PCNA rs25406 (P(trend) .03).
|
20150366 |
2010 |
|
rs662
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The frequencies of the PON1 genotypes and allelic variants of the polymorphisms PON1 L55M and PON1 Q192R did not differ significantly between patients with astrocytoma and meningioma and controls.
|
20723250 |
2010 |
|
rs854560
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The frequencies of the PON1 genotypes and allelic variants of the polymorphisms PON1 L55M and PON1 Q192R did not differ significantly between patients with astrocytoma and meningioma and controls.
|
20723250 |
2010 |
|
rs11012732
|
|
A |
0.810 |
GeneticVariation |
GWASDB |
We identified a new susceptibility locus for meningioma at 10p12.31 (MLLT10, rs11012732, odds ratio = 1.46, P(combined) = 1.88 × 10(-14)).
|
21804547 |
2011 |
|
rs11012732
|
|
A |
0.810 |
GeneticVariation |
GWASCAT |
We identified a new susceptibility locus for meningioma at 10p12.31 (MLLT10, rs11012732, odds ratio = 1.46, P(combined) = 1.88 × 10(-14)).
|
21804547 |
2011 |
|
rs11012732
|
|
|
0.810 |
GeneticVariation |
BEFREE |
We identified a new susceptibility locus for meningioma at 10p12.31 (MLLT10, rs11012732, odds ratio = 1.46, P(combined) = 1.88 × 10(-14)).
|
21804547 |
2011 |
|
rs267606541
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genetic analysis in a patient presenting with meningioma and familial isolated pituitary adenoma (FIPA) reveals selective involvement of the R81X mutation of the AIP gene in the pathogenesis of the pituitary tumor.
|
22527616 |
2012 |
|
rs202247756
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We combined genome-wide linkage analysis and exome sequencing, and we identified in suppressor of fused homolog (Drosophila), SUFU, a c.367C>T (p.Arg123Cys) mutation segregating with the meningiomas in the family.
|
22958902 |
2012 |