|
rs1799864
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The role of the C-C chemokine receptor 2 gene polymorphism V64I (CCR2-64I) in sarcoidosis in a Japanese population.
|
10351956 |
1999 |
|
rs763059810
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The role of the C-C chemokine receptor 2 gene polymorphism V64I (CCR2-64I) in sarcoidosis in a Japanese population.
|
10351956 |
1999 |
|
rs1800076
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Although R75Q was present in seven families, it was neither associated with the sarcoidosis phenotype in the German population (P=0.5), nor was it linked to sarcoidosis (P=0.54).
|
12404105 |
2002 |
|
rs3811381
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The GG genotype for the Pro1827Arg (C(5507)G) polymorphism was significantly associated with sarcoidosis in comparison to both control groups (odds ratio [OR] = 3.13; 95% confidence interval [CI] 1.49-6.69 versus healthy control subjects, and OR= 2.82, 95% CI 1.27-6.39 versus COPD control subjects).
|
12091241 |
2002 |
|
rs748009686
|
|
|
0.010 |
GeneticVariation |
BEFREE |
After correction for multiple testing, an IFNA17 polymorphism (551T-->G) was found to be associated with susceptibility to sarcoidosis (odds ratio 3.27 [95% CI: 1.44-7.46], P=0.004, P(c)=0.04), but not to tuberculosis.
|
15004750 |
2004 |
|
rs9298814
|
|
|
0.010 |
GeneticVariation |
BEFREE |
After correction for multiple testing, an IFNA17 polymorphism (551T-->G) was found to be associated with susceptibility to sarcoidosis (odds ratio 3.27 [95% CI: 1.44-7.46], P=0.004, P(c)=0.04), but not to tuberculosis.
|
15004750 |
2004 |
|
rs2076530
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Although rs2076530</span> was not associated with sarcoidosis in either African American sample, a three-locus haplotype that included rs2076530 was associated with sarcoidosis across all three study samples.
|
16080124 |
2005 |
|
rs2066845
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The aim of this work was to determine the frequencies of the three major NOD2/CARD 15 gene mutations (R702W, G908R and 1007fsinC) in a series of 76 subjects affected by IPF, and to compare them with those found in three groups of controls: a group with sarcoidosis (a disorder in which an involvement of the NOD2/CARD15 gene has already been investigated and rejected in different ethnic groups; 67 subjects) and two groups of healthy subjects (218 and 208 subjects, respectively), matched for gender, age, and ethnicity.
|
16315780 |
2005 |
|
rs2076530
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Significant differences were not demonstrable for the sarcoidosis associated splice-site variation (rs2076530 pallelic = 0.80) in our WG cohort.
|
16526951 |
2006 |
|
rs2076530
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Recent studies in sarcoidosis have identified association of a single nucleotide polymorphism (SNP) rs2076530 within BTNL2, a potential T-cell inhibitor, independent of the known DRB1 association.
|
16984233 |
2006 |
|
rs2066845
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Our results suggest that the G908R mutation of the CARD15/NOD2 gene, as well as the T allele and TT genotype of the CD14 promoter are associated with increased susceptibility for developing sarcoidosis.
|
16933467 |
2006 |
|
rs4986790
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Recently, an association between TLR-4 polymorphism Asp299Gly, leading to a change in the extracellular domain of the receptor and possible hyporesponsiveness to LPS, and a chronic course of sarcoidosis was found in German patients.
|
16879239 |
2006 |
|
rs4986790
|
|
|
0.030 |
GeneticVariation |
BEFREE |
We genotyped a total of 141 Caucasian patients with sarcoidosis and 141 healthy unrelated controls for the Asp299Gly and Thr399Ile polymorphisms in the TLR4 gene.
|
16487240 |
2006 |
|
rs2076530
|
|
|
0.900 |
GeneticVariation |
BEFREE |
In summary, HLA-DRB1*14, DRB1*12, and BTNL2 haplotype 4--but not rs2076530 A--are associated with non-Löfgren sarcoidosis.
|
17661910 |
2007 |
|
rs2066845
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Genotyping for CARD15 mutations R702W, G908R, and L1007fsinsC, also designated single nucleotide polymorphism (SNP) SNP8, SNP12 and SNP13, respectively, were performed by capillary electrophoresis single-strand confirmation polymorphism in 53 patients with histologically verified sarcoidosis and in 103 healthy controls.
|
16397396 |
2007 |
|
rs2075800
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A strong association was found between HSP-70/Hom rs2075800 G and uveitis in patients with sarcoidosis.
|
17591867 |
2007 |
|
rs1953600
|
|
|
0.800 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies ANXA11 as a new susceptibility locus for sarcoidosis.
|
19165924 |
2008 |
|
rs1049550
|
|
|
0.770 |
GeneticVariation |
BEFREE |
A common nonsynonymous SNP (rs1049550, C > T, [corrected] R230C) was found to be strongly associated with sarcoidosis.
|
19165924 |
2008 |
|
rs1049550
|
|
|
0.770 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies ANXA11 as a new susceptibility locus for sarcoidosis.
|
19165924 |
2008 |
|
rs2789679
|
|
|
0.720 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies ANXA11 as a new susceptibility locus for sarcoidosis.
|
19165924 |
2008 |
|
rs2573346
|
|
|
0.710 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies ANXA11 as a new susceptibility locus for sarcoidosis.
|
19165924 |
2008 |
|
rs2427216
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies ANXA11 as a new susceptibility locus for sarcoidosis.
|
19165924 |
2008 |
|
rs2784773
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies ANXA11 as a new susceptibility locus for sarcoidosis.
|
19165924 |
2008 |
|
rs7071579
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies ANXA11 as a new susceptibility locus for sarcoidosis.
|
19165924 |
2008 |
|
rs7091565
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies ANXA11 as a new susceptibility locus for sarcoidosis.
|
19165924 |
2008 |