|
rs10162249
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association study of African and European Americans implicates multiple shared and ethnic specific loci in sarcoidosis susceptibility.
|
22952805 |
2012 |
|
rs10213865
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs10213865 SNP was associated with sarcoidosis (P=0.008), and in silico analysis showed a complete linkage (r(2)=1, D'=1) with a functional nonsynonymous coding SNP in exon 6 (rs6897932, T244I).
|
19626041 |
2009 |
|
rs10399931
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Interestingly, it has been reported that rs10399931 (-329 G/A) of CHI3LI contributes to the inter-individual plasma YKL-40 levels in patients with sarcoidosis, and that rs4950928 (-131 C/G) is a susceptibility polymorphism for asthma and a decline in lung function.
|
19421404 |
2009 |
|
rs10399931
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In the present study, we have examined two functional variants of the promoter region of CHI3L1 gene (CHI3L1-1 (rs4950928) and CHI3L1-2 (rs10399931) that have been reported earlier to be associated with schizophrenia and sarcoidosis.
|
20300754 |
2011 |
|
rs10467674
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association study of African and European Americans implicates multiple shared and ethnic specific loci in sarcoidosis susceptibility.
|
22952805 |
2012 |
|
rs10484399
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
High-Density Genetic Mapping Identifies New Susceptibility Variants in Sarcoidosis Phenotypes and Shows Genomic-driven Phenotypic Differences.
|
26651848 |
2016 |
|
rs1049550
|
|
|
0.770 |
GeneticVariation |
BEFREE |
A common nonsynonymous SNP (rs1049550, C > T, [corrected] R230C) was found to be strongly associated with sarcoidosis.
|
19165924 |
2008 |
|
rs1049550
|
|
|
0.770 |
GeneticVariation |
BEFREE |
Annexin A11 gene polymorphism (R230C variant) and sarcoidosis in a Portuguese population.
|
24032725 |
2013 |
|
rs1049550
|
|
|
0.770 |
GeneticVariation |
BEFREE |
In block 2 (rs1049550-rs2573351), the T-C haplotype occurred significantly less frequently (p=0.001), whereas the C-C haplotypes occurred more frequently (p=0.0001) in patients with sarcoidosis than controls.
|
25056970 |
2014 |
|
rs1049550
|
|
|
0.770 |
GeneticVariation |
BEFREE |
We also identified a significant SNP-SNP interaction between rs1049550 and a sarcoidosis risk SNP (rs9268839) near the HLA-DRA locus.
|
23151485 |
2013 |
|
rs1049550
|
|
|
0.770 |
GeneticVariation |
BEFREE |
''C'' allele of SNP rs1049550 may be a risk factor for sarcoidosis in overall population.
|
27537711 |
2016 |
|
rs1049550
|
|
|
0.770 |
GeneticVariation |
BEFREE |
In this population of Caucasian patients with sarcoidosis, only DRB1*03 was associated with disease resolution after 2 years' follow-up, with no significant interactions found for susceptibility gene SNPs ANXA11 rs1049550 or BTNL2 rs2076530.
|
27662826 |
2018 |
|
rs1049550
|
|
|
0.770 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies ANXA11 as a new susceptibility locus for sarcoidosis.
|
19165924 |
2008 |
|
rs1049550
|
|
|
0.770 |
GeneticVariation |
BEFREE |
In line with the previous observation, ANXA11 mRNA expression was not deregulated in sarcoidosis</span> and was independent from rs1049550 variant.
|
21562576 |
2011 |
|
rs1050045
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SNP rs1050045 was significantly associated with sarcoidosis (corrected p=0.0215) in the validation panel and yielded a p-value of 9.22 × 10(-8) (OR 1.24) in the meta-analysis of the screening and validation stage.
|
22936702 |
2013 |
|
rs10741657
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The aim of this study was to investigate the association between single nucleotide polymorphisms (SNPs) in <i>CYP2R1</i> (rs10741657), <i>CYP27B1</i> (rs10877012), <i>DBP</i> (rs7041; rs4588), and <i>VDR</i> (rs2228570<i>)</i> genes and sarcoidosis, as well as the association between these SNPs and 25(OH)D levels in sarcoidosis patients.
|
31572458 |
2019 |
|
rs10877012
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Subjects carrying the CC genotype of <i>CYP27B1</i> rs10877012 have 10 times lower odds of suffering from sarcoidosis.
|
31572458 |
2019 |
|
rs11013452
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Haplotypic analyses of the C10ORF67-OTUD1 intergenic region revealed a strong inverse association of the variants rs1398024 and rs11013452 with sarcoidosis (odds ratio=0.52; P=0.01).
|
22972473 |
2012 |
|
rs111877852
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association study of African and European Americans implicates multiple shared and ethnic specific loci in sarcoidosis susceptibility.
|
22952805 |
2012 |
|
rs11209026
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Three IL23R SNPs, rs7517847 (intron 6), rs11465804 (intron 8), and rs11209026 (exon 9, c.1142G>A, p.Arg381Gln) were associated with sarcoidosis in our population (p<0.05): rs7517847 showed increased frequencies in sarcoidosis compared to controls, but rs11465804 and rs11209026 were decreased.
|
21846945 |
2011 |
|
rs112198380
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association study of African and European Americans implicates multiple shared and ethnic specific loci in sarcoidosis susceptibility.
|
22952805 |
2012 |
|
rs11244
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
High-Density Genetic Mapping Identifies New Susceptibility Variants in Sarcoidosis Phenotypes and Shows Genomic-driven Phenotypic Differences.
|
26651848 |
2016 |
|
rs112668322
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association study of African and European Americans implicates multiple shared and ethnic specific loci in sarcoidosis susceptibility.
|
22952805 |
2012 |
|
rs113520250
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association study of African and European Americans implicates multiple shared and ethnic specific loci in sarcoidosis susceptibility.
|
22952805 |
2012 |
|
rs113585425
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association study of African and European Americans implicates multiple shared and ethnic specific loci in sarcoidosis susceptibility.
|
22952805 |
2012 |