|
rs4680
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Effect of the COMT val158met polymorphism on white matter connectivity in patients with major depressive disorder.
|
23618651 |
2013 |
|
rs4680
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Meta-Analysis of the COMT Val158Met Polymorphism in Major Depressive Disorder: Effect of Ethnicity.
|
26803486 |
2016 |
|
rs4680
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Association between COMT (Val158Met) functional polymorphism and early onset in patients with major depressive disorder in a European multicenter genetic association study.
|
15583702 |
2005 |
|
rs4680
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In the present study, 256 patients with major depression (DSM-IV) of Caucasian descent were genotyped for the functional COMT val158met polymorphism and characterized for clinical response to antidepressive pharmacological treatment as measured by intra-individual changes of Hamilton Depression (HAM-D-21) scores over 6 weeks.
|
17522626 |
2008 |
|
rs4680
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Meta-analysis of the COMT Val158Met polymorphism in major depressive disorder: the role of gender.
|
26813412 |
2016 |
|
rs4680
|
|
|
0.100 |
GeneticVariation |
BEFREE |
This effect of rs4680 is similar to its observed influence on response to serotonergic and noradrenergic drug treatments in major depressive disorder.
|
19520435 |
2010 |
|
rs4680
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Responses to venlafaxine treatment in major depressive disorder were stratified by COMT genotypes (Val158Met, rs4680) in a randomized, double-blind, placebo-controlled clinical trial.
|
23706899 |
2013 |
|
rs4680
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Lack of influence of rs4680 (COMT) and rs6276 (DRD2) on diagnosis and clinical outcomes in patients with major depression.
|
24555772 |
2014 |
|
rs4680
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We investigated whether single nucleotide polymorphisms (SNPs) associated with neuroplasticity and activity of monoamine neurotransmitters, such as the brain-derived neurotrophic factor (BDNF, rs6265), the serotonin transporter (SLC6A4, rs25531), the tryptophan hydroxylase 1 (TPH1, rs1800532), the 5-hydroxytryptamine receptor 2A (HTR2A, rs6311, rs6313, rs7997012), and the catechol-O-methyltransferase (COMT, rs4680) genes, are associated with efficacy of transcranial direct current stimulation (tDCS) in major depression.
|
31721892 |
2019 |
|
rs4680
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In the present study, the effect of COMT val158met on response to electroconvulsive therapy (ECT) was analyzed in a sample of 104 Caucasian patients (f = 71, m = 33) with pharmacologically treatment-resistant Major Depression.
|
19309019 |
2010 |
|
rs4680
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Our study aims at replicating our previous finding of an association between COMT rs4680 G/A polymorphism and early onset major depression (MD).
|
21600957 |
2011 |
|
rs5569
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Meta-analysis on the Association Between Norepinephrine Transporter Gene rs2242446, rs5569 Polymorphisms and Risk of Major Depressive Disorder.
|
30292339 |
2018 |
|
rs5569
|
|
|
0.100 |
GeneticVariation |
BEFREE |
No association of the G1287A polymorphism in the norepinephrine transporter gene and susceptibility to major depressive disorder in a Japanese population.
|
17917281 |
2007 |
|
rs5569
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We analyzed the NET promoter T-182C polymorphism and another silent polymorphism G1287A in exon 9 of the NET gene with a polymerase chain reaction (PCR)-based method in 216 patients with major depression and 210 unrelated, age-and sex-matched healthy control subjects.
|
17353941 |
2007 |
|
rs5569
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Different combinations of T-182C and the G1287A polymorphisms of NET gene might increase morbidity risk of M</span>D subpopulations.
|
26061302 |
2015 |
|
rs5569
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In a case control association study we investigated the newly identified T-182C polymorphism and an already known G1287A polymorphism in exon 9 of the NET gene in a sample of 193 patients with major depression and 136 healthy, non-related controls.
|
11927173 |
2002 |
|
rs5569
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Relationship between G1287A of the NET Gene Polymorphisms and Brain Volume in Major Depressive Disorder: A Voxel-Based MRI Study.
|
26960194 |
2016 |
|
rs5569
|
|
|
0.100 |
GeneticVariation |
BEFREE |
One hundred and five patients with major depression and 74 unrelated matched controls were analyzed for a silent 1287G/A polymorphism (NET-8) in exon 9 of the NET gene.
|
10512149 |
1999 |
|
rs5569
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Association between T-182C, G1287A polymorphism in NET gene and suicidality in major depressive disorder in Chinese patients.
|
29703117 |
2018 |
|
rs5569
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In self-identified white patients with major depressive disorder (N=126) treated with open-label duloxetine (60-120 mg/d), a significant association of (P=0.020) of a composite risk score (based on SLC6A2 rs5569 [G1287A] AA, HTR1A rs6295 [C(-1019)G] GG, and COMT rs174697 AA/AG) with 17-item Hamilton Depression Rating Scale total score change from baseline to 12 weeks was observed.
|
22727709 |
2012 |
|
rs5569
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The present study suggests that the combined effect of rs2242446 and rs5569 in the NET gene could modify the response to the negative life events in triggering MD.
|
18779921 |
2008 |
|
rs5569
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Association between major depressive disorder and the norepinephrine transporter polymorphisms T-182C and G1287A: a meta-analysis.
|
23648227 |
2013 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In the current study, we examined BDNF polymorphisms (G-712A, C270T and Val66Met) in 202 patients with MD and 323 patients with schizophrenia.
|
21129438 |
2011 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Common genetic variants, such as the brain-derived neurotrophic factor (BDNF) Val/66/Met polymorphism (rs6265), are known to interact with environmental factors such as early adversity to increase the risk of subsequent major depression.
|
22844024 |
2012 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The current study looked at a population of patients with major depressive disorder (N = 107) to examine the association between the BDNF Val66Met polymorphism, resting state EEG alpha power, and depression severity.
|
23733090 |
2013 |