|
rs25531
|
|
|
0.020 |
GeneticVariation |
BEFREE |
49 patients with major depression and SSRI treatment were genotyped for the 5-HTTLPR locus including the rs25531.
|
22086748 |
2012 |
|
rs2273816
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Major depression was also associated with rs2273816 but only at the allele level.
|
22960338 |
2012 |
|
rs6883197
|
|
|
0.010 |
GeneticVariation |
BEFREE |
rs6883197 and rs259127 were significantly associated with schizophrenia, and rs12514461, rs259127, and rs7343 were associated with major depressive disorder.
|
24988482 |
2014 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Val66Met polymorphism association with serum BDNF and inflammatory biomarkers in major depression.
|
28656803 |
2018 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Val66Met polymorphism association with serum BDNF and inflammatory biomarkers in major depression.
|
28656803 |
2018 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A functional polymorphism of the brain-derived neurotrophic factor, BDNF Val66Met, is associated with risk for major depression alongside impairments in memory and selective attention.
|
18721847 |
2008 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A functional polymorphism of the brain-derived neurotrophic factor, BDNF Val66Met, is associated with risk for major depression alongside impairments in memory and selective attention.
|
18721847 |
2008 |
|
rs11568817
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A haplotype association study suggested that the rs11568817-rs130058 haplotype of the HTR1B gene is significantly associated with suicidal ideation in MD.
|
19897250 |
2009 |
|
rs130058
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A haplotype association study suggested that the rs11568817-rs130058 haplotype of the HTR1B gene is significantly associated with suicidal ideation in MD.
|
19897250 |
2009 |
|
rs16139
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A neuropeptide Y variant (rs16139) associated with major depressive disorder in replicate samples from Chinese Han population.
|
23468908 |
2013 |
|
rs2230912
|
|
|
0.040 |
GeneticVariation |
BEFREE |
A non-synonymous single nucleotide polymorphism, rs2230912 (P2RX7-E13A, G allele) and a microsatellite marker NBG6 were both previously found to be associated with bipolar disorder (P=0.00071 and 0.008, respectively). rs2230912 has also been found to show association with unipolar depression.
|
18268501 |
2009 |
|
rs772335034
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A non-synonymous single nucleotide polymorphism, rs2230912 (P2RX7-E13A, G allele) and a microsatellite marker NBG6 were both previously found to be associated with bipolar disorder (P=0.00071 and 0.008, respectively). rs2230912 has also been found to show association with unipolar depression.
|
18268501 |
2009 |
|
rs1176744
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A polymorphism encoding the variation Y129S in the 5-HT3B subunit exists in high frequency in the general population and has been shown to be inversely correlated to the incidence of major depression in women.
|
18184810 |
2008 |
|
rs6313
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Additional evidence for a role of serotonin (5-HT) in the pathogenesis of suicidal behavior is provided by a recent report that the 5-HT2A (HTR2A) T102C polymorphism was associated with suicidality in patients with major depression.
|
15469201 |
2004 |
|
rs737865
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Additionally, we observed an association between rs737865 alleles and early onset MD (p=0.04).
|
21600957 |
2011 |
|
rs6195
|
|
|
0.010 |
GeneticVariation |
BEFREE |
After conservative correction of Type-I-error to obtain reliable p values, one SNP in the NR3C1 gene, namely rs6195, showed a significant association with the presence of a major depression (p = 0.048) in females.
|
27549215 |
2017 |
|
rs1545843
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Against the background of stress impacting on the activity of the HPA axis, we have investigated alterations of adrenocorticotropic hormone (ACTH) and cortisol secretion in the combined dexamethasone/corticotrophin-releasing hormone (Dex/CRH) test as well as memory and attention performance in a sample of 248 patients with unipolar depression and 172 healthy control subjects genotyped for rs1545843.
|
22475622 |
2013 |
|
rs4236710
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Among the sites, rs4236710 (corrected Pgenotye = 0.015) and rs4512342 (Pallele = 0.03, Pgenotye = 0.045 after correction) were associated with schizophrenia, and rs2919375 (corrected Pgenotye = 0.004) was associated with major depressive disorder.
|
26888291 |
2016 |
|
rs2919375
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Among the sites, rs4236710 (corrected Pgenotye = 0.015) and rs4512342 (Pallele = 0.03, Pgenotye = 0.045 after correction) were associated with schizophrenia, and rs2919375 (corrected Pgenotye = 0.004) was associated with major depressive disorder.
|
26888291 |
2016 |
|
rs9825823
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype.
|
28049566 |
2017 |
|
rs68081839
|
|
|
0.010 |
GeneticVariation |
BEFREE |
An intronic variant at the GRIA4 locus, rs68081839, was significantly associated with ND-MD comorbidity (β = 0.69 [95% CI, 0.43-0.89], P = 1.53 × 10<sup>-8</sup>).
|
30287806 |
2018 |
|
rs111365677
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Analysis of 23andMe antidepressant efficacy survey data: implication of circadian rhythm and neuroplasticity in bupropion response.
|
27622933 |
2016 |
|
rs112106319
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Analysis of 23andMe antidepressant efficacy survey data: implication of circadian rhythm and neuroplasticity in bupropion response.
|
27622933 |
2016 |
|
rs112538845
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Analysis of 23andMe antidepressant efficacy survey data: implication of circadian rhythm and neuroplasticity in bupropion response.
|
27622933 |
2016 |
|
rs11924809
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Analysis of 23andMe antidepressant efficacy survey data: implication of circadian rhythm and neuroplasticity in bupropion response.
|
27622933 |
2016 |