|
rs34637584
|
|
|
0.010 |
GeneticVariation |
BEFREE |
1.Available evidence confirms that the LRRK2 variant rs34637584 is associated with less cognitive impairment in people with PD.2.GBA variants rs76763715 and rs421016 are associated with more severe cognitive impairment in people with PD.3.The GBA variants rs76763715, rs421016, rs387906315 and rs80356773 have been significantly associated with the onset of depressive symptoms in PD.
|
31292011 |
2020 |
|
rs76763715
|
|
|
0.010 |
GeneticVariation |
BEFREE |
1.Available evidence confirms that the LRRK2 variant rs34637584 is associated with less cognitive impairment in people with PD.2.GBA variants rs76763715 and rs421016 are associated with more severe cognitive impairment in people with PD.3.The GBA variants rs76763715, rs421016, rs387906315 and rs80356773 have been significantly associated with the onset of depressive symptoms in PD.
|
31292011 |
2020 |
|
rs421016
|
|
|
0.010 |
GeneticVariation |
BEFREE |
1.Available evidence confirms that the LRRK2 variant rs34637584 is associated with less cognitive impairment in people with PD.2.GBA variants rs76763715 and rs421016 are associated with more severe cognitive impairment in people with PD.3.The GBA variants rs76763715, rs421016, rs387906315 and rs80356773 have been significantly associated with the onset of depressive symptoms in PD.
|
31292011 |
2020 |
|
rs387906315
|
|
|
0.010 |
GeneticVariation |
BEFREE |
1.Available evidence confirms that the LRRK2 variant rs34637584 is associated with less cognitive impairment in people with PD.2.GBA variants rs76763715 and rs421016 are associated with more severe cognitive impairment in people with PD.3.The GBA variants rs76763715, rs421016, rs387906315 and rs80356773 have been significantly associated with the onset of depressive symptoms in PD.
|
31292011 |
2020 |
|
rs80356773
|
|
|
0.010 |
GeneticVariation |
BEFREE |
1.Available evidence confirms that the LRRK2 variant rs34637584 is associated with less cognitive impairment in people with PD.2.GBA variants rs76763715 and rs421016 are associated with more severe cognitive impairment in people with PD.3.The GBA variants rs76763715, rs421016, rs387906315 and rs80356773 have been significantly associated with the onset of depressive symptoms in PD.
|
31292011 |
2020 |
|
rs10830963
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We tested whether a common variant rs10830963 in the gene encoding Melatonin Receptor 1B influences the known association between depressive symptoms and glycaemic traits in a population-based sample from Western Finland.
|
30089436 |
2018 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A BDNF Val66Met × Harsh Parenting interaction predicted the rise in depressive symptoms across a 3-year period, whereas a 5-HTTLPR × Harsh Parenting interaction predicted greater frequency in elevated depressive symptoms.
|
27736236 |
2018 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A BDNF Val66Met × Harsh Parenting interaction predicted the rise in depressive symptoms across a 3-year period, whereas a 5-HTTLPR × Harsh Parenting interaction predicted greater frequency in elevated depressive symptoms.
|
27736236 |
2018 |
|
rs41423247
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A significant main effect of NR3C1-rs41423247 was found, where the C minor allele increased depressive symptoms at early abstinence.
|
27397864 |
2016 |
|
rs12720208
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A statistically significant association of the functional polymorphism in the FGF20 gene (rs12720208) with depressive symptoms was found.
|
30241547 |
2018 |
|
rs138191010
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A variant located on chromosome 7 was found to be associated with depressive symptoms at age 13 in ALSPAC (rs138191010: β = 0.142, p = 2.51 × 10<sup>-8</sup>), although this was not replicated.
|
28859627 |
2017 |
|
rs1290141855
|
|
|
0.010 |
GeneticVariation |
BEFREE |
After correcting for Bonferroni multiple tests, we found associations between the MAOA c.1460C>T (SNP 1137070), COMT c.472G>A (SNP 4680), MTHFR c.677C>T (SNP 1801133) and ESR1 454(-351) A>G (SNP 9340799) polymorphisms to mild and moderate depressive symptoms in menopausal women.
|
26620113 |
2016 |
|
rs757522886
|
|
|
0.010 |
GeneticVariation |
BEFREE |
After correcting for Bonferroni multiple tests, we found associations between the MAOA c.1460C>T (SNP 1137070), COMT c.472G>A (SNP 4680), MTHFR c.677C>T (SNP 1801133) and ESR1 454(-351) A>G (SNP 9340799) polymorphisms to mild and moderate depressive symptoms in menopausal women.
|
26620113 |
2016 |
|
rs4680
|
|
|
0.060 |
GeneticVariation |
BEFREE |
After correcting for Bonferroni multiple tests, we found associations between the MAOA c.1460C>T (SNP 1137070), COMT c.472G>A (SNP 4680), MTHFR c.677C>T (SNP 1801133) and ESR1 454(-351) A>G (SNP 9340799) polymorphisms to mild and moderate depressive symptoms in menopausal women.
|
26620113 |
2016 |
|
rs1200746244
|
|
|
0.010 |
GeneticVariation |
BEFREE |
After correcting for Bonferroni multiple tests, we found associations between the MAOA c.1460C>T (SNP 1137070), COMT c.472G>A (SNP 4680), MTHFR c.677C>T (SNP 1801133) and ESR1 454(-351) A>G (SNP 9340799) polymorphisms to mild and moderate depressive symptoms in menopausal women.
|
26620113 |
2016 |
|
rs1403522266
|
|
|
0.010 |
GeneticVariation |
BEFREE |
After correcting for Bonferroni multiple tests, we found associations between the MAOA c.1460C>T (SNP 1137070), COMT c.472G>A (SNP 4680), MTHFR c.677C>T (SNP 1801133) and ESR1 454(-351) A>G (SNP 9340799) polymorphisms to mild and moderate depressive symptoms in menopausal women.
|
26620113 |
2016 |
|
rs749865093
|
|
|
0.010 |
GeneticVariation |
BEFREE |
After correcting for Bonferroni multiple tests, we found associations between the MAOA c.1460C>T (SNP 1137070), COMT c.472G>A (SNP 4680), MTHFR c.677C>T (SNP 1801133) and ESR1 454(-351) A>G (SNP 9340799) polymorphisms to mild and moderate depressive symptoms in menopausal women.
|
26620113 |
2016 |
|
rs1217691063
|
|
|
0.010 |
GeneticVariation |
BEFREE |
After correcting for Bonferroni multiple tests, we found associations between the MAOA c.1460C>T (SNP 1137070), COMT c.472G>A (SNP 4680), MTHFR c.677C>T (SNP 1801133) and ESR1 454(-351) A>G (SNP 9340799) polymorphisms to mild and moderate depressive symptoms in menopausal women.
|
26620113 |
2016 |
|
rs749437638
|
|
|
0.010 |
GeneticVariation |
BEFREE |
After correcting for Bonferroni multiple tests, we found associations between the MAOA c.1460C>T (SNP 1137070), COMT c.472G>A (SNP 4680), MTHFR c.677C>T (SNP 1801133) and ESR1 454(-351) A>G (SNP 9340799) polymorphisms to mild and moderate depressive symptoms in menopausal women.
|
26620113 |
2016 |
|
rs2230912
|
|
|
0.020 |
GeneticVariation |
BEFREE |
After correcting for multiple testing, only the association of the P2RX7 Gln460Arg (rs2230912) polymorphism with depressive symptoms remained significant.
|
18801407 |
2008 |
|
rs25531
|
|
|
0.040 |
GeneticVariation |
BEFREE |
After stratification for 5-HTTLPR/rs25531, only in S'S' individuals high depressive symptoms were actually associated with sleep onset latency complaint.
|
25297871 |
2015 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Among Aβ+ women, ε4 carriers reported greater anxiety symptoms than non-ε4 carriers (d = 0.83), and female BDNF rs6265 Val66 Met allele carriers reported greater depressive symptoms (d = 0.29).
|
27742526 |
2016 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Among Aβ+ women, ε4 carriers reported greater anxiety symptoms than non-ε4 carriers (d = 0.83), and female BDNF rs6265 Val66 Met allele carriers reported greater depressive symptoms (d = 0.29).
|
27742526 |
2016 |
|
rs2606345
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Among Caucasian women, those with the CYP1A1 rs2606345 CC and AC genotypes had approximately 2-fold greater odds of having depressive symptoms than did those with the AA genotype (95% confidence intervals [CIs], 1.33 to 4.66 and 1.25 to 3.14, respectively).
|
16949393 |
2006 |
|
rs7582472
|
|
|
0.010 |
GeneticVariation |
BEFREE |
An association between symptoms of depression and rs7582472 (near to MGAT5 and NCKAP5) was replicated in two independent samples, but other replication findings were less consistent.
|
22628180 |
2012 |