|
rs2651899
|
|
|
0.880 |
GeneticVariation |
BEFREE |
Our major findings suggest that PRDM16 rs2651899 polymorphism is associated with the risk of migraine.
|
31557325 |
2020 |
|
rs2651899
|
|
|
0.880 |
GeneticVariation |
BEFREE |
This research study showed that rs2651899 is a potential genetic marker for migraine susceptibility in MO and female subgroup at both genotypic and allelic level in the North Indian population and found that rs10166942 variant may be a potential marker for MA and male subgroup.
|
30635810 |
2019 |
|
rs2651899
|
|
|
0.880 |
GeneticVariation |
BEFREE |
Our data indicates that rs1835740 and MTDH might be involved in neurovascular headaches in general whilst rs2651899 is specifically related to migraine.
|
30382894 |
2018 |
|
rs2651899
|
|
|
0.880 |
GeneticVariation |
BEFREE |
We report significant influence of rs1835740, LRP1 rs11172113 and PRDM16 rs2651899 polymorphisms on migraine susceptibility in the North Indian population.
|
24266335 |
2014 |
|
rs2651899
|
|
|
0.880 |
GeneticVariation |
BEFREE |
We identified the minor allele of rs2651899 located in PRDM16 to be associated with migraine (P = .005, odds ratio = 1.382, 95% confidence interval = 1.100-1.736), the association remain significant after Bonferroni correction.
|
24666033 |
2014 |
|
rs2651899
|
|
|
0.880 |
GeneticVariation |
BEFREE |
The meta-analysis confirmed the previous three genome-wide significant associated SNPs (rs2651899, rs10166942 and rs11172113) to confer risk of migraine.
|
23294458 |
2013 |
|
rs2651899
|
|
C |
0.880 |
GeneticVariation |
GWASCAT |
Genome-wide meta-analysis identifies new susceptibility loci for migraine.
|
23793025 |
2013 |
|
rs2651899
|
|
C |
0.880 |
GeneticVariation |
GWASDB |
Genome-wide meta-analysis identifies new susceptibility loci for migraine.
|
23793025 |
2013 |
|
rs2651899
|
|
|
0.880 |
GeneticVariation |
BEFREE |
The potential function of the fourth variant rs2651899 (PRDM16) in migraine is unclear.
|
22072275 |
2012 |
|
rs2651899
|
|
C |
0.880 |
GeneticVariation |
GWASCAT |
The associations at rs2651899 and rs10166942 were specific for migraine compared with non-migraine headache.
|
21666692 |
2011 |
|
rs2651899
|
|
C |
0.880 |
GeneticVariation |
GWASDB |
The associations at rs2651899 and rs10166942 were specific for migraine compared with non-migraine headache.
|
21666692 |
2011 |
|
rs2651899
|
|
|
0.880 |
GeneticVariation |
BEFREE |
The associations at rs2651899 and rs10166942 were specific for migraine compared with non-migraine headache.
|
21666692 |
2011 |
|
rs10166942
|
|
|
0.870 |
GeneticVariation |
BEFREE |
This research study showed that rs2651899 is a potential genetic marker for migraine susceptibility in MO and female subgroup at both genotypic and allelic level in the North Indian population and found that rs10166942 variant may be a potential marker for MA and male subgroup.
|
30635810 |
2019 |
|
rs10166942
|
|
|
0.870 |
GeneticVariation |
BEFREE |
We infer strong positive selection, in agreement with ancient DNA showing high frequency of the allele in Europe 3,000 to 8,000 years ago. rs10166942 is important phenotypically because its ancestral allele is protective of migraine.
|
29723195 |
2018 |
|
rs10166942
|
|
|
0.870 |
GeneticVariation |
GWASCAT |
Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine.
|
27322543 |
2016 |
|
rs10166942
|
|
|
0.870 |
GeneticVariation |
BEFREE |
On the other hand, TRPM8 rs10166942 and TGFBR2 rs7640543 variants did not have significant influence on migraine susceptibility in the North Indian population.
|
24266335 |
2014 |
|
rs10166942
|
|
|
0.870 |
GeneticVariation |
BEFREE |
To further replicate the GWAS findings, we investigated the 3 variants rs2651899 (1p36.32, PRDM16), rs10166942 (2q37.1, TRPM8), and rs11172113 (12q13.3, LRP1) for their association with migraine in the Chinese Han population.
|
24666033 |
2014 |
|
rs10166942
|
|
|
0.870 |
GeneticVariation |
BEFREE |
Recent genome-wide association studies (GWAS) have identified 3 loci in or near PRDM16 (1p36.32, rs2651899), LRP1 (12q13.3, rs11172113) and TRPM8 (2q37.1, rs10166942) in the population-based Women's Genome Health Study (WGHS) of migraine, and 2 loci in or near TRPM8 and LRP1 were repeated in European GWAS study.
|
24021092 |
2014 |
|
rs10166942
|
|
|
0.870 |
GeneticVariation |
GWASDB |
Genome-wide meta-analysis identifies new susceptibility loci for migraine.
|
23793025 |
2013 |
|
rs10166942
|
|
|
0.870 |
GeneticVariation |
BEFREE |
The meta-analysis confirmed the previous three genome-wide significant associated SNPs (rs2651899, rs101</span>66942 and rs11172113) to confer risk of migraine.
|
23294458 |
2013 |
|
rs10166942
|
|
|
0.870 |
GeneticVariation |
GWASDB |
Genome-wide association analysis identifies susceptibility loci for migraine without aura.
|
22683712 |
2012 |
|
rs10166942
|
|
|
0.870 |
GeneticVariation |
GWASCAT |
Genome-wide association analysis identifies susceptibility loci for migraine without aura.
|
22683712 |
2012 |
|
rs10166942
|
|
|
0.870 |
GeneticVariation |
BEFREE |
The associations at rs2651899 and rs10166942 were specific for migraine compared with non-migraine headache.
|
21666692 |
2011 |
|
rs10166942
|
|
T |
0.870 |
GeneticVariation |
GWASCAT |
The associations at rs2651899 and rs10166942 were specific for migraine compared with non-migraine headache.
|
21666692 |
2011 |
|
rs10166942
|
|
T |
0.870 |
GeneticVariation |
GWASDB |
The associations at rs2651899 and rs10166942 were specific for migraine compared with non-migraine headache.
|
21666692 |
2011 |