Disease: Lupus Erythematosus, Systemic
Source: ALL
Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Num. diseases
rs2476601
AP4B1-AS1 ; PTPN22
0.498 0.800 1 113834946 missense variant A/G snv 0.93 0.93 121
rs535586
EHMT2 ; CYP21A2
0.882 0.160 6 31892560 splice region variant T/A;C snv 0.77 3
rs659445
EHMT2 ; CYP21A2 ; C2
0.882 0.160 6 31896527 intron variant G/A;C snv 0.77 0.76 3
rs437179
SKIV2L ; CYP21A2
0.882 0.160 6 31961237 missense variant A/C snv 0.76 0.78 3
rs1799983
NOS3
0.430 0.880 7 150999023 missense variant T/A;G snv 0.75 246
rs1883832
CD40
0.581 0.680 20 46118343 5 prime UTR variant T/C snv 0.75 0.80 52
rs708035
IRAK2
0.925 0.120 3 10234479 missense variant T/A snv 0.73 0.70 2
rs1059702
IRAK1
0.807 0.280 X 154018741 missense variant A/G snv 0.72 7
rs2910164
MIR3142HG ; MIR146A
0.447 0.880 5 160485411 mature miRNA variant C/G snv 0.71; 4.1E-06 0.70 193
rs3810936
TNFSF15
0.742 0.320 9 114790605 synonymous variant T/C snv 0.71 0.75 12
rs25487
XRCC1
0.441 0.800 19 43551574 missense variant T/C snv 0.68 0.71 205
rs1061170
CFH
0.561 0.720 1 196690107 missense variant C/T snv 0.68 0.64 72
rs1042522
TP53
0.426 0.800 17 7676154 missense variant G/C;T snv 0.67 242
rs7192
HLA-DRA
0.827 0.200 6 32443869 missense variant T/G snv 0.64 0.61 7
rs1748033
PADI4
0.925 0.120 1 17336167 missense variant T/C;G snv 0.63; 4.0E-06 2
rs2227981
LOC105373977 ; PDCD1
0.763 0.400 2 241851121 synonymous variant A/C;G snv 1.6E-04; 0.63 12
rs2228570
VDR
0.521 0.760 12 47879112 start lost A/C;G;T snv 0.63 99
rs9268832
HLA-DRB9
0.882 0.160 6 32460012 non coding transcript exon variant T/C snv 0.61 0.59 4
rs660550
SLC44A4 ; CYP21A2
0.882 0.160 6 31869500 intron variant C/A;G snv 0.60 3
rs2242665
CYP21A2 ; SLC44A4
0.882 0.160 6 31871532 missense variant C/T snv 0.60 0.60 3
rs644827
SLC44A4 ; CYP21A2
0.882 0.160 6 31870664 missense variant T/C snv 0.60 0.60 3
rs185819
TNXB
0.851 0.200 6 32082290 missense variant T/A;C;G snv 8.2E-06; 0.58; 4.1E-06 10
rs2277798
UBASH3A
0.925 0.120 21 42403997 missense variant A/G snv 0.55 0.60 3
rs509749
LY9
0.925 0.120 1 160823770 missense variant A/G snv 0.54 0.55 2
rs1884444
IL23R ; C1orf141
0.637 0.600 1 67168129 missense variant G/T snv 0.52 0.51 34