|
Malignant Neoplasms
|
0.090 |
Biomarker
|
group |
BEFREE |
The roles of USP39 in human cancer have been widely investigated.
|
30898977 |
2019 |
|
Malignant Neoplasms
|
0.090 |
Biomarker
|
group |
BEFREE |
Furthermore, USP39 is proved to be associated with the proliferation of malignant tumors.
|
31637536 |
2019 |
|
Malignant Neoplasms
|
0.090 |
Biomarker
|
group |
BEFREE |
Ubiquitin‑specific protease 39 (USP39), as one of the deubiquitinating enzymes (DUBs), exhibits aberrant an expression and has oncogenic functions in several types of cancer.
|
31180526 |
2019 |
|
Malignant Neoplasms
|
0.090 |
Biomarker
|
group |
BEFREE |
Ubiquitin-specific peptidase 39 (USP39) has been reported to participate in the mitotic spindle checkpoint and the process of cytokinesis. and has been identified as a therapeutic target for various types of cancer.
|
29556295 |
2018 |
|
Malignant Neoplasms
|
0.090 |
Biomarker
|
group |
BEFREE |
Ubiquitin specific peptidase 39 (USP39) serves important roles in mRNA processing and is involved in tumorigenesis of multiple solid malignancies.
|
29328477 |
2018 |
|
Malignant Neoplasms
|
0.090 |
Biomarker
|
group |
BEFREE |
USP39 Deubiquitinase Is Essential for <i>KRAS</i> Oncogene-driven Cancer.
|
28154181 |
2017 |
|
Malignant Neoplasms
|
0.090 |
Biomarker
|
group |
BEFREE |
These results uncover the critical role of USP39 in regulating cancer cell mitosis and indicate USP39 is critical for osteosarcoma tumorigenesis.
|
28403900 |
2017 |
|
Malignant Neoplasms
|
0.090 |
Biomarker
|
group |
BEFREE |
Knockdown of USP39 in PCa cells inhibited cancer colony formation and tumor cell growth, and induced G2/M arrest and cell apoptosis.
|
26959883 |
2016 |
|
Malignant Neoplasms
|
0.090 |
AlteredExpression
|
group |
BEFREE |
Previous studies have shown that ubiquitin-specific protease 39 (USP39) is upregulated in several cancers and associated with tumor malignant characters.
|
27629785 |
2016 |
|
Neoplasms
|
0.060 |
Biomarker
|
group |
BEFREE |
In vivo animal models revealed that the subcutaneous transplantation and intraperitoneal injection of USP39‑overexpressing ES2 cells increased tumor burden with or without treatment with carboplatin.
|
31180526 |
2019 |
|
Neoplasms
|
0.060 |
Biomarker
|
group |
BEFREE |
Knockdown of USP39 in glioma cells demonstrated that the protein promoted cell growth, invasion and migration in vitro and in a tumor model in nude mice.
|
31332287 |
2019 |
|
Primary malignant neoplasm
|
0.060 |
Biomarker
|
group |
BEFREE |
Ubiquitin‑specific protease 39 (USP39), as one of the deubiquitinating enzymes (DUBs), exhibits aberrant an expression and has oncogenic functions in several types of cancer.
|
31180526 |
2019 |
|
Primary malignant neoplasm
|
0.060 |
Biomarker
|
group |
BEFREE |
The roles of USP39 in human cancer have been widely investigated.
|
30898977 |
2019 |
|
Primary malignant neoplasm
|
0.060 |
Biomarker
|
group |
BEFREE |
Ubiquitin-specific peptidase 39 (USP39) has been reported to participate in the mitotic spindle checkpoint and the process of cytokinesis. and has been identified as a therapeutic target for various types of cancer.
|
29556295 |
2018 |
|
Neoplasms
|
0.060 |
Biomarker
|
group |
BEFREE |
USP39 knockdown inhibited xenograft tumor growth in nude mice and led to the downregulation of the transcription factor Forkhead Box M1 (FoxM1).
|
28413501 |
2017 |
|
Primary malignant neoplasm
|
0.060 |
Biomarker
|
group |
BEFREE |
USP39 Deubiquitinase Is Essential for <i>KRAS</i> Oncogene-driven Cancer.
|
28154181 |
2017 |
|
Primary malignant neoplasm
|
0.060 |
Biomarker
|
group |
BEFREE |
These results uncover the critical role of USP39 in regulating cancer cell mitosis and indicate USP39 is critical for osteosarcoma tumorigenesis.
|
28403900 |
2017 |
|
Neoplasms
|
0.060 |
AlteredExpression
|
group |
BEFREE |
Ubiquitin-specific protease 39 is overexpressed in human lung cancer and promotes tumor cell proliferation in vitro.
|
27629785 |
2016 |
|
Neoplasms
|
0.060 |
Biomarker
|
group |
BEFREE |
In this study, we aimed to investigate the functional relationship between OSCC and a potential tumor related gene ubiquitin-specific proteases 39 (USP39).
|
26835714 |
2016 |
|
Primary malignant neoplasm
|
0.060 |
Biomarker
|
group |
BEFREE |
Knockdown of USP39 in PCa cells inhibited cancer colony formation and tumor cell growth, and induced G2/M arrest and cell apoptosis.
|
26959883 |
2016 |
|
Neoplasms
|
0.060 |
AlteredExpression
|
group |
BEFREE |
We also found that p-Cdc2 was decreased in the USP39-overexpressing cells and was upregulated in the xenografted tumors derived from the HepG2/KD cells from nude mice.
|
26081192 |
2015 |
|
Liver carcinoma
|
0.050 |
Biomarker
|
disease |
BEFREE |
Previous studies have reported that ubiquitin-specific peptidase 39 (USP39) is generally overexpressed in a variety of cancers, including hepatocellular carcinoma, gastric cancer and so forth.
|
31637536 |
2019 |
|
Liver carcinoma
|
0.050 |
Biomarker
|
disease |
BEFREE |
Expression of Concern to: Lentivirus mediated silencing of Ubiquitin Specific Peptidase 39 inhibits cell proliferation of human hepatocellular carcinoma cells in vitro.
|
29933754 |
2018 |
|
Liver carcinoma
|
0.050 |
Biomarker
|
disease |
BEFREE |
The results suggest that knockdown of USP39 inhibits the growth of HCC <i>in vitro</i> and <i>in vivo</i>, potentially through the induction of G2/M arrest by regulating the pre-mRNA splicing of FoxM1.
|
28413501 |
2017 |
|
Liver carcinoma
|
0.050 |
AlteredExpression
|
disease |
BEFREE |
The USP39 expression was significantly higher in the tumor tissues compared to the adjacent normal tissues, and was strongly associated with the pathological grade of HCC.
|
26081192 |
2015 |