ADORA1, adenosine A1 receptor, 134

N. diseases: 121; N. variants: 12
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0270192
Disease: Perinatal Subarachnoid Hemorrhage
Perinatal Subarachnoid Hemorrhage 		0.300 Biomarker phenotype CTD_human Attenuation of cerebral vasospasm and secondary injury by 17beta-estradiol following experimental subarachnoid hemorrhage. 18950269 2009
CUI: C0472383
Disease: Subarachnoid Hemorrhage, Spontaneous
Subarachnoid Hemorrhage, Spontaneous 		0.300 Biomarker phenotype CTD_human Attenuation of cerebral vasospasm and secondary injury by 17beta-estradiol following experimental subarachnoid hemorrhage. 18950269 2009
CUI: C0751530
Disease: Subarachnoid Hemorrhage, Aneurysmal
Subarachnoid Hemorrhage, Aneurysmal 		0.300 Biomarker phenotype CTD_human Attenuation of cerebral vasospasm and secondary injury by 17beta-estradiol following experimental subarachnoid hemorrhage. 18950269 2009
CUI: C0795688
Disease: Subarachnoid Hemorrhage, Intracranial
Subarachnoid Hemorrhage, Intracranial 		0.300 Biomarker phenotype CTD_human Attenuation of cerebral vasospasm and secondary injury by 17beta-estradiol following experimental subarachnoid hemorrhage. 18950269 2009
CUI: C0020649
Disease: Hypotension
Hypotension 		0.300 Biomarker phenotype CTD_human Hypotensive effects of intravenously administered uridine and cytidine in conscious rats: involvement of adenosine receptors. 18313046 2008
CUI: C0033054
Disease: Prenatal Exposure Delayed Effects
Prenatal Exposure Delayed Effects 		0.300 Biomarker disease CTD_human Perinatal caffeine, acting on maternal adenosine A(1) receptors, causes long-lasting behavioral changes in mouse offspring. 19092996 2008
CUI: C0428977
Disease: Bradycardia
Bradycardia 		0.300 Biomarker phenotype CTD_human Hypotensive effects of intravenously administered uridine and cytidine in conscious rats: involvement of adenosine receptors. 18313046 2008
CUI: C0038587
Disease: Substance Withdrawal Syndrome
Substance Withdrawal Syndrome 		0.300 Biomarker disease CTD_human Influence of adenosine receptor agonists on benzodiazepine withdrawal signs in mice. 16226742 2005
CUI: C0086189
Disease: Drug Withdrawal Symptoms
Drug Withdrawal Symptoms 		0.300 Biomarker phenotype CTD_human Influence of adenosine receptor agonists on benzodiazepine withdrawal signs in mice. 16226742 2005
CUI: C0087169
Disease: Withdrawal Symptoms
Withdrawal Symptoms 		0.300 Biomarker phenotype CTD_human Influence of adenosine receptor agonists on benzodiazepine withdrawal signs in mice. 16226742 2005
CUI: C0013221
Disease: Drug toxicity
Drug toxicity 		0.300 Biomarker group CTD_human Do adenosine receptors play a role in amitriptyline-induced cardiovascular toxicity in rats? 15641640 2004
CUI: C0020649
Disease: Hypotension
Hypotension 		0.300 Biomarker phenotype CTD_human Do adenosine receptors play a role in amitriptyline-induced cardiovascular toxicity in rats? 15641640 2004
CUI: C0041755
Disease: Adverse reaction to drug
Adverse reaction to drug 		0.300 Biomarker group CTD_human Do adenosine receptors play a role in amitriptyline-induced cardiovascular toxicity in rats? 15641640 2004
CUI: C0242973
Disease: Ventricular Dysfunction
Ventricular Dysfunction 		0.300 Biomarker phenotype CTD_human Do adenosine receptors play a role in amitriptyline-induced cardiovascular toxicity in rats? 15641640 2004
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.300 Therapeutic disease CTD_human Role of adenosine in delayed preconditioning of myocardium. 12160945 2002
CUI: C0007370
Disease: Catalepsy
Catalepsy 		0.300 Therapeutic disease CTD_human Effect of adenosine receptor agonists and antagonists on morphine-induced catalepsy in mice. 9407998 1997
CUI: C0233612
Disease: Waxy flexibility
Waxy flexibility 		0.300 Therapeutic phenotype CTD_human Effect of adenosine receptor agonists and antagonists on morphine-induced catalepsy in mice. 9407998 1997
CUI: C0520679
Disease: Sleep Apnea, Obstructive
Sleep Apnea, Obstructive 		0.210 Biomarker disease BEFREE However, little is known about whether ADORA1 takes part in the course of neuronal cell injury after intermittent hypoxia exposure which was the main pathological characteristic of OSAHS. 29380238 2018
CUI: C0520679
Disease: Sleep Apnea, Obstructive
Sleep Apnea, Obstructive 		0.210 Biomarker disease RGD Sleep fragmentation impairs ventilatory long-term facilitation via adenosine A1 receptors. 18787037 2008
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia 		0.200 Biomarker phenotype RGD Adenosine A1 receptor agonists reduce hyperalgesia after spinal cord injury in rats. 20065990 2010
CUI: C0042510
Disease: Ventricular Fibrillation
Ventricular Fibrillation 		0.200 Biomarker disease RGD [Adenosine induces ventricular arrythmias in hearts with chronic chagas cardiomyopathy]. 20334814 2010
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy 		0.200 Biomarker disease RGD Protective effect of adenosine in diabetic neuropathic pain is mediated through adenosine A1-receptors. 19552053 2009
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.200 Biomarker group RGD Ischaemic and pharmacological preconditionings protect liver via adenosine and redox status following hepatic ischaemia/reperfusion in rats. 18307414 2008
CUI: C0242698
Disease: Ventricular Dysfunction, Left
Ventricular Dysfunction, Left 		0.200 Biomarker phenotype RGD Adenosine A1 receptor expression during the transition from compensated pressure overload hypertrophy to heart failure. 17211253 2007
CUI: C0007785
Disease: Cerebral Infarction
Cerebral Infarction 		0.200 Biomarker disease RGD Moderate cerebral venous congestion induces rapid cerebral protection via adenosine A1 receptor activation. 17067559 2006