ADORA1, adenosine A1 receptor, 134

N. diseases: 121; N. variants: 12
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.310 Biomarker disease BEFREE Taken together, these results indicate that metformin suppresses human colorectal cancer growth by inducing apoptosis via ADORA1, which provide evidence the anti-neoplastic effects of metformin in the treatment of human colorectal cancer. 27814614 2017
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.310 GeneticVariation disease BEFREE Therefore, we investigated the contribution of genetic variations of ADORA1 to the pathophysiological mechanisms of Japanese schizophrenia patients. 19820430 2009
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.310 Biomarker disease PSYGENET Therefore, we investigated the contribution of genetic variations of ADORA1 to the pathophysiological mechanisms of Japanese schizophrenia patients. 19820430 2009
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.310 GeneticVariation disease UNIPROT
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack 		0.300 Therapeutic disease CTD_human Decreased extracellular adenosine levels lead to loss of hypoxia-induced neuroprotection after repeated episodes of exposure to hypoxia. 23437309 2013
CUI: C0027746
Disease: Nerve Degeneration
Nerve Degeneration 		0.300 Therapeutic phenotype CTD_human Decreased extracellular adenosine levels lead to loss of hypoxia-induced neuroprotection after repeated episodes of exposure to hypoxia. 23437309 2013
CUI: C0238281
Disease: Middle Cerebral Artery Syndrome
Middle Cerebral Artery Syndrome 		0.300 Therapeutic phenotype CTD_human Decreased extracellular adenosine levels lead to loss of hypoxia-induced neuroprotection after repeated episodes of exposure to hypoxia. 23437309 2013
CUI: C0472381
Disease: Posterior Circulation Transient Ischemic Attack
Posterior Circulation Transient Ischemic Attack 		0.300 Therapeutic disease CTD_human Decreased extracellular adenosine levels lead to loss of hypoxia-induced neuroprotection after repeated episodes of exposure to hypoxia. 23437309 2013
CUI: C0740376
Disease: Middle Cerebral Artery Thrombosis
Middle Cerebral Artery Thrombosis 		0.300 Therapeutic disease CTD_human Decreased extracellular adenosine levels lead to loss of hypoxia-induced neuroprotection after repeated episodes of exposure to hypoxia. 23437309 2013
CUI: C0740391
Disease: Middle Cerebral Artery Occlusion
Middle Cerebral Artery Occlusion 		0.300 Therapeutic disease CTD_human Decreased extracellular adenosine levels lead to loss of hypoxia-induced neuroprotection after repeated episodes of exposure to hypoxia. 23437309 2013
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery 		0.300 Therapeutic disease CTD_human Decreased extracellular adenosine levels lead to loss of hypoxia-induced neuroprotection after repeated episodes of exposure to hypoxia. 23437309 2013
CUI: C0751019
Disease: Carotid Circulation Transient Ischemic Attack
Carotid Circulation Transient Ischemic Attack 		0.300 Therapeutic disease CTD_human Decreased extracellular adenosine levels lead to loss of hypoxia-induced neuroprotection after repeated episodes of exposure to hypoxia. 23437309 2013
CUI: C0751020
Disease: Transient Ischemic Attack, Vertebrobasilar Circulation
Transient Ischemic Attack, Vertebrobasilar Circulation 		0.300 Therapeutic disease CTD_human Decreased extracellular adenosine levels lead to loss of hypoxia-induced neuroprotection after repeated episodes of exposure to hypoxia. 23437309 2013
CUI: C0751021
Disease: Crescendo Transient Ischemic Attacks
Crescendo Transient Ischemic Attacks 		0.300 Therapeutic disease CTD_human Decreased extracellular adenosine levels lead to loss of hypoxia-induced neuroprotection after repeated episodes of exposure to hypoxia. 23437309 2013
CUI: C0751022
Disease: Brain Stem Ischemia, Transient
Brain Stem Ischemia, Transient 		0.300 Therapeutic disease CTD_human Decreased extracellular adenosine levels lead to loss of hypoxia-induced neuroprotection after repeated episodes of exposure to hypoxia. 23437309 2013
CUI: C0751845
Disease: Middle Cerebral Artery Embolus
Middle Cerebral Artery Embolus 		0.300 Therapeutic phenotype CTD_human Decreased extracellular adenosine levels lead to loss of hypoxia-induced neuroprotection after repeated episodes of exposure to hypoxia. 23437309 2013
CUI: C0751846
Disease: Left Middle Cerebral Artery Infarction
Left Middle Cerebral Artery Infarction 		0.300 Therapeutic phenotype CTD_human Decreased extracellular adenosine levels lead to loss of hypoxia-induced neuroprotection after repeated episodes of exposure to hypoxia. 23437309 2013
CUI: C0751847
Disease: Embolic Infarction, Middle Cerebral Artery
Embolic Infarction, Middle Cerebral Artery 		0.300 Therapeutic phenotype CTD_human Decreased extracellular adenosine levels lead to loss of hypoxia-induced neuroprotection after repeated episodes of exposure to hypoxia. 23437309 2013
CUI: C0751848
Disease: Thrombotic Infarction, Middle Cerebral Artery
Thrombotic Infarction, Middle Cerebral Artery 		0.300 Therapeutic phenotype CTD_human Decreased extracellular adenosine levels lead to loss of hypoxia-induced neuroprotection after repeated episodes of exposure to hypoxia. 23437309 2013
CUI: C0751849
Disease: Right Middle Cerebral Artery Infarction
Right Middle Cerebral Artery Infarction 		0.300 Therapeutic phenotype CTD_human Decreased extracellular adenosine levels lead to loss of hypoxia-induced neuroprotection after repeated episodes of exposure to hypoxia. 23437309 2013
CUI: C0917805
Disease: Transient Cerebral Ischemia
Transient Cerebral Ischemia 		0.300 Therapeutic disease CTD_human Decreased extracellular adenosine levels lead to loss of hypoxia-induced neuroprotection after repeated episodes of exposure to hypoxia. 23437309 2013
CUI: C1527335
Disease: Transient Ischemic Attack, Anterior Circulation
Transient Ischemic Attack, Anterior Circulation 		0.300 Therapeutic disease CTD_human Decreased extracellular adenosine levels lead to loss of hypoxia-induced neuroprotection after repeated episodes of exposure to hypoxia. 23437309 2013
CUI: C0013182
Disease: Drug Allergy
Drug Allergy 		0.300 Biomarker group CTD_human Adenosine deaminase and adenosine receptor polymorphisms in aspirin-intolerant asthma. 19019667 2009
CUI: C0022116
Disease: Ischemia
Ischemia 		0.300 Biomarker phenotype CTD_human Adenosine A1 receptor (AR-A1) expression is increased following ischemia and may represent an endogenous neuroprotective effect. 18950269 2009
CUI: C0038525
Disease: Subarachnoid Hemorrhage
Subarachnoid Hemorrhage 		0.300 Biomarker disease CTD_human Attenuation of cerebral vasospasm and secondary injury by 17beta-estradiol following experimental subarachnoid hemorrhage. 18950269 2009