|
Colorectal Neoplasms
|
0.700 |
Biomarker
|
group |
BEFREE |
It is concluded that the patterns of expression of E-cadherin and alpha- and beta-catenin are very similar in colorectal neoplasms.
|
9349236 |
1997 |
|
Colorectal Neoplasms
|
0.700 |
AlteredExpression
|
group |
BEFREE |
JMJD2D interacts with β-catenin to activate transcription of its target genes and promote CRC cell proliferation, migration, and invasion, as well as formation of colorectal tumors in mice.
|
30472235 |
2019 |
|
Colorectal Neoplasms
|
0.700 |
Biomarker
|
group |
CTD_human |
More frequent beta-catenin gene mutations in adenomas than in aberrant crypt foci or adenocarcinomas in the large intestines of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-treated rats.
|
10965019 |
2000 |
|
Colorectal Neoplasms
|
0.700 |
Biomarker
|
group |
LHGDN |
MUC1 and nuclear beta-catenin are coexpressed at the invasion front of colorectal carcinomas and are both correlated with tumor prognosis.
|
15102686 |
2004 |
|
Colorectal Neoplasms
|
0.700 |
AlteredExpression
|
group |
BEFREE |
MUC13 promotes the development of colitis-associated colorectal tumors via β-catenin activity.
|
31427737 |
2019 |
|
Colorectal Neoplasms
|
0.700 |
AlteredExpression
|
group |
BEFREE |
MUC5AC/β-catenin expression and KRAS gene alteration in laterally spreading colorectal tumors.
|
23112547 |
2012 |
|
Colorectal Neoplasms
|
0.700 |
Biomarker
|
group |
LHGDN |
Mutated in colorectal cancer, a putative tumor suppressor for serrated colorectal cancer, selectively represses beta-catenin-dependent transcription.
|
18591935 |
2008 |
|
Colorectal Neoplasms
|
0.700 |
Biomarker
|
group |
BEFREE |
Mutations in APC and beta-catenin, despite occurring in the same genetic pathway, show differing biological properties, a phenomenon that has previously been demonstrated in colorectal neoplasms.
|
12414520 |
2002 |
|
Colorectal Neoplasms
|
0.700 |
AlteredExpression
|
group |
LHGDN |
Mutations in APC, CTNNB1 and K-ras genes and expression of hMLH1 in sporadic colorectal carcinomas from the Netherlands Cohort Study.
|
16356174 |
2005 |
|
Colorectal Neoplasms
|
0.700 |
Biomarker
|
group |
LHGDN |
Novel cross talk of Kruppel-like factor 4 and beta-catenin regulates normal intestinal homeostasis and tumor repression.
|
16507986 |
2006 |
|
Colorectal Neoplasms
|
0.700 |
Biomarker
|
group |
LHGDN |
Nuclear beta-catenin accumulation as a prognostic factor in Dukes' D human colorectal cancers.
|
15254684 |
2004 |
|
Colorectal Neoplasms
|
0.700 |
AlteredExpression
|
group |
LHGDN |
Nuclear beta-catenin expression as a prognostic factor in advanced colorectal carcinoma.
|
18609711 |
2008 |
|
Colorectal Neoplasms
|
0.700 |
AlteredExpression
|
group |
LHGDN |
Nuclear beta-catenin expression is closely related to ulcerative growth of colorectal carcinoma.
|
11953860 |
2002 |
|
Colorectal Neoplasms
|
0.700 |
GeneticVariation
|
group |
BEFREE |
Our results indicate that somatic beta-catenin activating mutations contribute only to a minor part of human colorectal tumors and that germline beta-catenin mutations do not play a role in the variability of symptoms in FAP.
|
9591632 |
1998 |
|
Colorectal Neoplasms
|
0.700 |
Biomarker
|
group |
BEFREE |
OVOL2 is a colorectal tumor suppressor that blocks WNT signaling by facilitating the recruitment of histone deacetylase 1 to the TCF4-β-catenin complex.
|
26619963 |
2016 |
|
Colorectal Neoplasms
|
0.700 |
Biomarker
|
group |
BEFREE |
p16INK4a is a beta-catenin target gene and indicates low survival in human colorectal tumors.
|
18951899 |
2009 |
|
Colorectal Neoplasms
|
0.700 |
AlteredExpression
|
group |
LHGDN |
Pin1 overexpression in colorectal cancer and its correlation with aberrant beta-catenin expression.
|
16124054 |
2005 |
|
Colorectal Neoplasms
|
0.700 |
AlteredExpression
|
group |
LHGDN |
Positive KL-6 mucin expression combined with decreased membranous beta-catenin expression indicates worse prognosis in colorectal carcinoma.
|
18949395 |
2008 |
|
Colorectal Neoplasms
|
0.700 |
Biomarker
|
group |
BEFREE |
Previous studies have revealed that β‑catenin is associated with TRAIL resistance in melanoma and colorectal tumors.
|
30132512 |
2018 |
|
Colorectal Neoplasms
|
0.700 |
Biomarker
|
group |
LHGDN |
Prognostic and diagnostic significance of beta-catenin nuclear immunostaining in colorectal cancer.
|
14977843 |
2004 |
|
Colorectal Neoplasms
|
0.700 |
Biomarker
|
group |
LHGDN |
Prognostic significance of beta-catenin in colorectal cancer with liver metastasis.
|
17168211 |
2006 |
|
Colorectal Neoplasms
|
0.700 |
Biomarker
|
group |
CTD_human |
Proteomic analysis of intestinal epithelial cells expressing stabilized beta-catenin.
|
12907644 |
2003 |
|
Colorectal Neoplasms
|
0.700 |
AlteredExpression
|
group |
LHGDN |
Regulation of AKT1 expression by beta-catenin/Tcf/Lef signaling in colorectal cancer cells.
|
15888491 |
2005 |
|
Colorectal Neoplasms
|
0.700 |
AlteredExpression
|
group |
LHGDN |
Relation of E-cadherin and beta-catenin expression to pit pattern in colorectal cancer.
|
15289833 |
2004 |
|
Colorectal Neoplasms
|
0.700 |
Biomarker
|
group |
CTD_human |
Resveratrol prevents tumorigenesis in mouse model of Kras activated sporadic colorectal cancer by suppressing oncogenic Kras expression.
|
25280562 |
2014 |