|
Tauopathies
|
0.020 |
Biomarker
|
group |
BEFREE |
CHIP could rescue phosphorylated tau-induced cell death, and therefore the CHIP-Hsc70 complex may provide a new therapeutic target for the tauopathies.
|
14612456 |
2004 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Hsc70 down-regulation might reflect a functional integration of the overexpressed Hsp70 on the basis of a chaperone network so that only acute induction will provide Hsp70 that can improve tumor cell lysability.
|
14678977 |
2003 |
|
Acute kidney injury
|
0.200 |
Biomarker
|
disease |
RGD |
73-kDa molecular chaperone HSP73 is a direct target of antibiotic gentamicin.
|
14966137 |
2004 |
|
Neoplasms
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Tumors with weak (+) HSC70 protein staining were more frequent in the carriers of the polymorphic 1541-1542delGT allele than in the homozygotes of the major allele (20% vs. 6%, P=0.05 by Fisher's exact test).
|
14991745 |
2004 |
|
Breast Carcinoma
|
0.070 |
Biomarker
|
disease |
BEFREE |
Somatic mutations of 11q23.3-linked constitutive heat shock protein 70 gene (HSPA8 alias HSC70) are detected by others in breast carcinomas.
|
14991745 |
2004 |
|
Carcinoma
|
0.010 |
GeneticVariation
|
group |
BEFREE |
To examine whether intragenic, somatic mutations of HSPA8 occur in lung carcinomas, we sequenced its exons 2-8, with adjacent intronic sequences, in a series of DNA samples from non-small-cell lung cancers (NSCLC).
|
14991745 |
2004 |
|
Malignant neoplasm of lung
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Intronic polymorphism (1541-1542delGT) of the constitutive heat shock protein 70 gene has functional significance and shows evidence of association with lung cancer risk.
|
14991745 |
2004 |
|
Carcinoma of lung
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Intronic polymorphism (1541-1542delGT) of the constitutive heat shock protein 70 gene has functional significance and shows evidence of association with lung cancer risk.
|
14991745 |
2004 |
|
Primary malignant neoplasm of lung
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Intronic polymorphism (1541-1542delGT) of the constitutive heat shock protein 70 gene has functional significance and shows evidence of association with lung cancer risk.
|
14991745 |
2004 |
|
Herpes Simplex Infections
|
0.030 |
Biomarker
|
group |
LHGDN |
Nuclear sequestration of cellular chaperone and proteasomal machinery during herpes simplex virus type 1 infection.
|
15194794 |
2004 |
|
Infection
|
0.020 |
Biomarker
|
group |
LHGDN |
Nuclear sequestration of cellular chaperone and proteasomal machinery during herpes simplex virus type 1 infection.
|
15194794 |
2004 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
In addition to melanoma, gastric and uterus cancer tissues exhibited higher HSP73 mRNA expression on a matched tumour/normal cDNA array than their normal counterparts which was statistically significant.
|
15254721 |
2004 |
|
melanoma
|
0.030 |
Biomarker
|
disease |
BEFREE |
HSP73 immunostaining was stronger in melanoma metastases when compared with acquired melanocytic nevi which was statistically significant.
|
15254721 |
2004 |
|
Neoplasm Metastasis
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
HSP73 immunostaining was stronger in melanoma metastases when compared with acquired melanocytic nevi which was statistically significant.
|
15254721 |
2004 |
|
Melanocytic nevus
|
0.010 |
Biomarker
|
disease |
BEFREE |
HSP73 immunostaining was stronger in melanoma metastases when compared with acquired melanocytic nevi which was statistically significant.
|
15254721 |
2004 |
|
Uterine Cancer
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
In addition to melanoma, gastric and uterus cancer tissues exhibited higher HSP73 mRNA expression on a matched tumour/normal cDNA array than their normal counterparts which was statistically significant.
|
15254721 |
2004 |
|
Secondary Neoplasm
|
0.010 |
Biomarker
|
group |
BEFREE |
HSP73 immunostaining was stronger in melanoma metastases when compared with acquired melanocytic nevi which was statistically significant.
|
15254721 |
2004 |
|
Melanocytic nevus of skin
|
0.010 |
Biomarker
|
disease |
BEFREE |
HSP73 immunostaining was stronger in melanoma metastases when compared with acquired melanocytic nevi which was statistically significant.
|
15254721 |
2004 |
|
Liver Failure, Acute
|
0.200 |
Biomarker
|
disease |
RGD |
Induction of molecular chaperones in carbon tetrachloride-treated rat liver: implications in protection against liver damage.
|
15270078 |
2004 |
|
Squamous cell carcinoma
|
0.300 |
Biomarker
|
disease |
CTD_human |
Proteomics of buccal squamous cell carcinoma: the involvement of multiple pathways in tumorigenesis.
|
15274141 |
2004 |
|
Mouth Neoplasms
|
0.300 |
Biomarker
|
group |
CTD_human |
Proteomics of buccal squamous cell carcinoma: the involvement of multiple pathways in tumorigenesis.
|
15274141 |
2004 |
|
Malignant neoplasm of mouth
|
0.300 |
Biomarker
|
group |
CTD_human |
Proteomics of buccal squamous cell carcinoma: the involvement of multiple pathways in tumorigenesis.
|
15274141 |
2004 |
|
Colonic Neoplasms
|
0.010 |
AlteredExpression
|
group |
LHGDN |
Expression of methionine aminopeptidase 2, N-myristoyltransferase, and N-myristoyltransferase inhibitor protein 71 in HT29.
|
15336565 |
2004 |
|
Malignant neoplasm of stomach
|
0.310 |
Biomarker
|
disease |
CTD_human |
Diverse proteomic alterations in gastric adenocarcinoma.
|
15378696 |
2004 |
|
Adenocarcinoma
|
0.300 |
Biomarker
|
group |
CTD_human |
Diverse proteomic alterations in gastric adenocarcinoma.
|
15378696 |
2004 |