|
Stomach Neoplasms
|
0.010 |
Biomarker
|
group |
LHGDN |
WNT2B: comparative integromics and clinical applications (Review).
|
16273293 |
2005 |
|
Acute lymphocytic leukemia
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Reverse transcription polymerase chain reaction (RT-PCR) analysis of B-cell progenitor acute lymphoblastic leukaemia (ALL) cells revealed expression of Wnt genes, including WNT2B in 33%, WNT5A in 42%, WNT10B in 58% and WNT16B in 25% of cases.
|
17614820 |
2007 |
|
Allergic rhinitis (disorder)
|
0.010 |
Biomarker
|
disease |
BEFREE |
A total of 39 single nucleotide polymorphisms (SNPs) distributed over the genes PIP, WNT2B, CLC and PLUNC were selected from dbSNP, genotyped and investigated for associations with allergic rhinitis.
|
19650845 |
2010 |
|
Triglycerides measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
|
23063622 |
2012 |
|
High density lipoprotein measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
|
23063622 |
2012 |
|
Serum HDL cholesterol measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
|
23063622 |
2012 |
|
Primary malignant neoplasm
|
0.040 |
Biomarker
|
group |
BEFREE |
Cancer gene therapy using an adenoviral vector expressing short hairpin RNA (shRNA) against Wnt2B was, therefore, found to have a strong antitumour effect against Wnt2B2-overexpressing tumours.
|
21646015 |
2012 |
|
Malignant Neoplasms
|
0.030 |
Biomarker
|
group |
BEFREE |
Cancer gene therapy using an adenoviral vector expressing short hairpin RNA (shRNA) against Wnt2B was, therefore, found to have a strong antitumour effect against Wnt2B2-overexpressing tumours.
|
21646015 |
2012 |
|
Neoplasm Metastasis
|
0.020 |
Biomarker
|
phenotype |
BEFREE |
These data suggest that Wnt2B indeed plays an important role in ovarian cancer metastasis and drug resistance.
|
22635028 |
2012 |
|
Tumor Progression
|
0.020 |
AlteredExpression
|
phenotype |
BEFREE |
Wnt2B overexpression is thought to affect tumour progression through the activation of the canonical Wnt pathway.
|
21646015 |
2012 |
|
Tumor Progression
|
0.020 |
AlteredExpression
|
phenotype |
BEFREE |
Wnt2B overexpression is thought to be involved in tumor progression through the activation of the canonical Wingless and INT-1 signaling pathway.
|
22635028 |
2012 |
|
ovarian neoplasm
|
0.020 |
Biomarker
|
disease |
BEFREE |
These data suggest that Wnt2B indeed plays an important role in ovarian cancer metastasis and drug resistance.
|
22635028 |
2012 |
|
Malignant neoplasm of ovary
|
0.010 |
Biomarker
|
disease |
BEFREE |
These data suggest that Wnt2B indeed plays an important role in ovarian cancer metastasis and drug resistance.
|
22635028 |
2012 |
|
Carcinoma, Ovarian Epithelial
|
0.010 |
Biomarker
|
disease |
BEFREE |
These data suggest that Wnt2B indeed plays an important role in ovarian cancer metastasis and drug resistance.
|
22635028 |
2012 |
|
Nasopharyngeal carcinoma
|
0.040 |
Biomarker
|
disease |
BEFREE |
Finally, the clinical significance of miRNA-324-3p and WNT2B was investigated in NPC tissues.
|
23583221 |
2013 |
|
Virus Diseases
|
0.010 |
AlteredExpression
|
group |
BEFREE |
Here we show that secretion of WNT2B and WNT9B and stabilization of β-catenin (CTNNB1) upon virus infection negatively regulate expression of representative inducible genes IFNB1, IFIT1 and TNF in a CTNNB1-dependent effector mechanism.
|
23785285 |
2013 |
|
Nasopharyngeal carcinoma
|
0.040 |
AlteredExpression
|
disease |
BEFREE |
We concluded that miR-185-3p contributed to the radioresistance of NPC via modulation of WNT2B expression in vitro.
|
25297925 |
2014 |
|
Myopia
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
The amounts of Wnt2b, Fzd5 and β-catenin mRNA and protein were significantly greater in form-deprived myopia eyes than in control eyes.DKK-1 (antagonist) reduced the myopic shift in refractive error and increase in axial elongation, whereas Norrin had the opposite effect in FDM eyes.
|
24755605 |
2014 |
|
Neoplasms
|
0.010 |
Biomarker
|
group |
BEFREE |
Using normal mucosa, the association of ACSL5 and Wnt2B was seen, but in intestinal neoplasias the mechanism was only rudimentarily observed.
|
25356045 |
2014 |
|
Refractive Errors
|
0.010 |
AlteredExpression
|
group |
BEFREE |
The amounts of Wnt2b, Fzd5 and β-catenin mRNA and protein were significantly greater in form-deprived myopia eyes than in control eyes.DKK-1 (antagonist) reduced the myopic shift in refractive error and increase in axial elongation, whereas Norrin had the opposite effect in FDM eyes.
|
24755605 |
2014 |
|
Pancreatic carcinoma
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer.
|
26098869 |
2015 |
|
Diastolic blood pressure
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.
|
27618452 |
2016 |
|
Systolic Pressure
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.
|
27618452 |
2016 |
|
Neural Tube Defects
|
0.010 |
AlteredExpression
|
group |
BEFREE |
The results demonstrated that the transcriptional activities of Wnt2b and Wnt7b were abnormally upregulated in mouse fetuses with NTDs and, in the GC‑rich promoters of these genes, histone 3 lysine 4 (H3K4) acetylation was enriched, whereas H3K27 trimethylation was reduced.
|
26548512 |
2016 |
|
Physical Activity Measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.
|
28448500 |
2017 |