ZNF750, zinc finger protein 750, 79755

N. diseases: 20; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Seborrhea-Like Dermatitis with Psoriasiform Elements
0.600 Biomarker disease GENOMICS_ENGLAND Association analysis identifies ZNF750 regulatory variants in psoriasis. 22185198 2011
Seborrhea-Like Dermatitis with Psoriasiform Elements
0.600 GermlineCausalMutation disease ORPHANET Seborrhea-like dermatitis with psoriasiform elements caused by a mutation in ZNF750, encoding a putative C2H2 zinc finger protein. 16751772 2006
Seborrhea-Like Dermatitis with Psoriasiform Elements
0.600 Biomarker disease GENOMICS_ENGLAND Seborrhea-like dermatitis with psoriasiform elements caused by a mutation in ZNF750, encoding a putative C2H2 zinc finger protein. 16751772 2006
Seborrhea-Like Dermatitis with Psoriasiform Elements
0.600 Biomarker disease CTD_human
CUI: C0036508
Disease: Seborrheic dermatitis
Seborrheic dermatitis
0.100 Biomarker disease HPO
CUI: C0870082
Disease: Hyperkeratosis
Hyperkeratosis
0.100 Biomarker disease HPO
CUI: C4553962
Disease: Hyperkeratosis, CTCAE
Hyperkeratosis, CTCAE
0.100 Biomarker phenotype HPO
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.060 Biomarker group BEFREE Zinc-finger protein 750 (ZNF750) is a potential tumor suppressor in oral squamous cell carcinoma (OSCC). 31545271 2019
Squamous cell carcinoma of esophagus
0.060 AlteredExpression disease BEFREE This study also found that 44/106(4151%), 37/106 (34.91%), 39/106(36.79%) of ESCC showed heterogeneous expression of ZNF750, EP300 and MTOR respectively by IHC, 8/12(66.67%), 8/12(66.67%), 4/12(33.33%), 4/12(33.33%) of ZNF750, EP300, MTOR and KMT2D respectively by RNAscope, IHC and RNAscope could successfully detect a high prevalence of ITH. 30528923 2019
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.060 Biomarker group BEFREE ZNF750 could modulate the tumor vascular microenvironment to inhibit the oral squamous cells carcinoma malignant progression. 29890464 2018
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.060 AlteredExpression group BEFREE ZNF750, a transcriptional regulator of epidermal differentiation, has been identified as a tumor suppressor in esophageal squamous cell carcinoma (ESCC). 29216641 2018
Squamous cell carcinoma of esophagus
0.060 Biomarker disease BEFREE The low expression of ZNF750 was significantly associated with a poor prognosis, and ZNF750 expression may, therefore, be a reliable prognostic biomarker in ESCC. 29216641 2018
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.060 Biomarker group BEFREE ZNF750 is a lineage-specific tumour suppressor in squamous cell carcinoma. 27819679 2017
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.060 AlteredExpression group BEFREE Overexpression of tumor suppressor gene ZNF750 inhibits oral squamous cell carcinoma metastasis. 29113187 2017
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.060 Biomarker group BEFREE ZNF750, an epidermal differentiation regulator, has been suggested to act as a tumor suppressor of esophageal squamous cell carcinoma (ESCC). 28558382 2017
Squamous cell carcinoma of esophagus
0.060 AlteredExpression disease BEFREE The aim of the present study was to evaluate the relationship between ZNF750 expression and response to CRT in ESCC. 28558382 2017
Squamous cell carcinoma of esophagus
0.060 Biomarker disease BEFREE The present authors previously identified a novel candidate tumor suppressor gene, zinc finger protein 750 (<i>ZNF750</i>), in esophageal squamous cell carcinoma (ESCC) (1). 28789412 2017
Squamous cell carcinoma of esophagus
0.060 GeneticVariation disease BEFREE Combined analysis from current and previous genomic ESCC studies indicated more frequent ZNF750 mutation in diagnosed cases with LN metastasis than in those without metastasis (14% versus 3.4%, n = 629, P = 1.78 × 10<sup>-5</sup> ). 28608921 2017
Squamous cell carcinoma of esophagus
0.060 Biomarker disease BEFREE Functional analyses suggest roles for several genes (CBX4, CBX8, AJUBA, and ZNF750) in ESCC. 25839328 2015
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.040 Biomarker disease BEFREE ZNF750 inhibited the malignant progression of oral squamous cell carcinoma by regulating tumor vascular microenvironment. 29890464 2018
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.040 AlteredExpression disease BEFREE The expression level of ZNF750 in tissue specimens from OSCC patients was detected by immunohistochemistry. 29416636 2018
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.040 Biomarker disease BEFREE Overexpression of tumor suppressor gene ZNF750 inhibits oral squamous cell carcinoma metastasis. 29113187 2017
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.040 Biomarker disease BEFREE ZNF750 is a lineage-specific tumour suppressor in squamous cell carcinoma. 27819679 2017
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.030 Biomarker group BEFREE The present study is to explore the mechanism of ZNF750 to suppress the tumor malignant process by regulation tumor microenvironment. 29890464 2018
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.030 Biomarker group BEFREE Zinc-finger protein 750 (ZNF750) is the potential anti-cancer gene in oral squamous cell carcinoma (OSCC). 29416636 2018