|
Alcoholic Intoxication, Chronic
|
0.120 |
GeneticVariation
|
disease |
GWASDB |
"ALDH2 is associated to alcohol dependence and is the major genetic determinant of ""daily maximum drinks"" in a GWAS study of an isolated rural Chinese sample."
|
24277619 |
2014 |
|
Conventional (Clear Cell) Renal Cell Carcinoma
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
<b>Background:</b> Clear cell renal cell carcinoma (ccRCC) is the most prevalent histologic subtype of kidney cancers in adults, which could be divided into two distinct subgroups according to the <i>BRCA1 associated protein-1</i> (<i>BAP1</i>) mutation status.
|
28900502 |
2017 |
|
Malignant neoplasm of kidney
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
<b>Background:</b> Clear cell renal cell carcinoma (ccRCC) is the most prevalent histologic subtype of kidney cancers in adults, which could be divided into two distinct subgroups according to the <i>BRCA1 associated protein-1</i> (<i>BAP1</i>) mutation status.
|
28900502 |
2017 |
|
Uveal melanoma
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Uveal melanoma (UM) remains without effective therapy at the metastatic stage, which is associated with <i>BAP-1</i> (BRCA1 associated protein) mutations.
|
31146482 |
2019 |
|
Retinitis Pigmentosa
|
0.010 |
Biomarker
|
disease |
BEFREE |
IMP dehydrogenase-linked retinitis pigmentosa.
|
18600550 |
2008 |
|
Myocardial Infarction
|
0.450 |
Biomarker
|
disease |
BEFREE |
BRCA-1 associated protein (BRAP), a newly identified risk gene for MI, aggravates the inflammatory response in atherosclerosis.
|
23356535 |
2013 |
|
Arteriosclerosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
BRCA-1 associated protein (BRAP), a newly identified risk gene for MI, aggravates the inflammatory response in atherosclerosis.
|
23356535 |
2013 |
|
Atherosclerosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
BRCA-1 associated protein (BRAP), a newly identified risk gene for MI, aggravates the inflammatory response in atherosclerosis.
|
23356535 |
2013 |
|
Myocardial Infarction
|
0.450 |
GeneticVariation
|
disease |
GWASDB |
A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese.
|
24916648 |
2015 |
|
Myocardial Infarction
|
0.450 |
GeneticVariation
|
disease |
GWASCAT |
A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese.
|
24916648 |
2015 |
|
Coronary heart disease
|
0.120 |
GeneticVariation
|
disease |
GWASDB |
A genome-wide association study of a coronary artery disease risk variant.
|
23364394 |
2013 |
|
Hepatitis B
|
0.100 |
GeneticVariation
|
disease |
GWASDB |
A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population.
|
21750111 |
2011 |
|
Metabolic Syndrome X
|
0.030 |
Biomarker
|
disease |
BEFREE |
A phenomics-based strategy identifies loci on APOC1, BRAP, and PLCG1 associated with metabolic syndrome phenotype domains.
|
22022282 |
2011 |
|
Intracranial Atherosclerosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Acetazolamide reactivity on <sup>123</sup> I-IMP SPECT is used to detect misery perfusion due to intracranial atherosclerosis.
|
29215168 |
2018 |
|
Chronic Kidney Diseases
|
0.010 |
GeneticVariation
|
group |
BEFREE |
After adjustment for clinical factors, kidney function was associated with BRAP rs3782886 and SPATA5L1 rs2467853 and the GRS for CKD that we developed was associated CKD.
|
29016630 |
2017 |
|
Bone marrow depression
|
0.010 |
Biomarker
|
disease |
BEFREE |
All patients receive folic acid 5 mg daily whilst on the trial IMP to reduce the risk of bone marrow depression.
|
29402332 |
2018 |
|
Hyperactive behavior
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
Also, administration with SB or IMP could reverse the hyperactivity of hypothalamic-pituitary-adrenal axis as well as decreased inflammatory cytokines with improved antioxidant status.
|
31353549 |
2019 |
|
Neoplasms
|
0.060 |
Biomarker
|
group |
BEFREE |
Although discussed using variable terminology, cutaneous BRCA1-associated protein (BAP1)-inactivated melanocytic tumor (BIMT) has been considered a discrete diagnostic entity since 2011.
|
31233225 |
2019 |
|
Bacteremia
|
0.010 |
Biomarker
|
disease |
BEFREE |
Although in-hospital mortality rates were similar between cases and controls (14.3% versus 13.3%), the in-hospital mortality of patients with IMP-producing E. cloacae-caused bacteremia was significantly higher (40%) than the rate in controls.
|
24709261 |
2014 |
|
Glioma
|
0.030 |
Biomarker
|
disease |
BEFREE |
Autophagy suppression sensitizes glioma cells to IMP dehydrogenase inhibition-induced apoptotic death.
|
27818246 |
2017 |
|
C-reactive protein measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.
|
27286809 |
2016 |
|
Low density lipoprotein cholesterol measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.
|
27286809 |
2016 |
|
Breast Cancer, Familial
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
BRIP1 is a BRCA1 associated protein that is mutated in a fraction of familial breast cancer and Fanconi anemia cases.
|
20567916 |
2010 |
|
Fanconi Anemia
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
BRIP1 is a BRCA1 associated protein that is mutated in a fraction of familial breast cancer and Fanconi anemia cases.
|
20567916 |
2010 |
|
FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder)
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
BRIP1 is a BRCA1 associated protein that is mutated in a fraction of familial breast cancer and Fanconi anemia cases.
|
20567916 |
2010 |