|
ABLEPHARON-MACROSTOMIA SYNDROME
|
|
0.010 |
GeneticVariation
|
BEFREE |
We tested the hypothesis that haplotypes, as determined by tagSNPs, in NOS3 would be differentially represented in individuals with and without AMS sampled at the Janai Purnima Festival at Lake Gosain Kunda, Nepal, at 4380 m. Seven SNPs were tested, and a highly significant association (p = 0.004) was found for genotypes of the commonly studied missense polymorphism Glu298Asp (rs 1799983; G/T transversion at base 894).
|
19775216 |
2009 |
|
Acute Chest Syndrome
|
|
0.020 |
GeneticVariation
|
BEFREE |
The aim of our study was to evaluate the role of eNOS-786T > C, 894G > T and 4a/4b polymorphisms in modulating platelet phenotype in 1442 acute coronary syndrome (ACS) patients on dual antiplatelet therapy, previously investigated in relation to platelet function.
|
19891529 |
2009 |
|
Acute Chest Syndrome
|
|
0.020 |
GeneticVariation
|
BEFREE |
Polymorphisms in the NOS3 gene (eNOS) -786T>C, 894G>T and intron 4 a/b VNTR can be associated with a higher susceptibility for ACS.
|
22475779 |
2012 |
|
Acute Coronary Syndrome
|
|
0.030 |
GeneticVariation
|
BEFREE |
Influence of endothelial nitric oxide synthase gene polymorphisms (G894T, 4a4b, T-786C) and hyperhomocysteinemia on the predisposition to acute coronary syndromes.
|
14999203 |
2004 |
|
Acute Coronary Syndrome
|
|
0.030 |
GeneticVariation
|
BEFREE |
Interaction between endothelial nitric oxide synthase gene polymorphisms (-786T>C, 894G>T and intron 4 a/b) and cardiovascular risk factors in acute coronary syndromes.
|
22475779 |
2012 |
|
Acute Coronary Syndrome
|
|
0.030 |
GeneticVariation
|
BEFREE |
The aim of our study was to evaluate the role of eNOS-786T > C, 894G > T and 4a/4b polymorphisms in modulating platelet phenotype in 1442 acute coronary syndrome (ACS) patients on dual antiplatelet therapy, previously investigated in relation to platelet function.
|
19891529 |
2009 |
|
Acute hepatitis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Hence, the iNOS C150T polymorphism and the eNOS G894T polymorphism and high levels of iNOS and eNOS are associated with an increased risk of HEV-related acute hepatitis and liver failure.
|
24215170 |
2014 |
|
Acute mountain sickness
|
|
0.010 |
GeneticVariation
|
BEFREE |
Genotype at the missense G894T polymorphism (Glu298Asp) in the NOS3 gene is associated with susceptibility to acute mountain sickness.
|
19775216 |
2009 |
|
Acute myocardial infarction
|
|
0.030 |
GeneticVariation
|
BEFREE |
In contrast to previous reports, homozygosity for the Asp298 variant of the 894G>T polymorphism in the eNOS gene was not found to be associated with risk of AMI, extent of CAD and in-hospital mortality after AMI.
|
18495009 |
2008 |
|
Acute myocardial infarction
|
|
0.030 |
GeneticVariation
|
BEFREE |
To investigate the association of allelic variants produced by the G894T transversion in eNOS (rs1799983) with post-AMI variables.
|
26002446 |
2015 |
|
Acute myocardial infarction
|
|
0.030 |
GeneticVariation
|
BEFREE |
Recent reports have suggested that the Glu298Asp polymorphism in exon 7 of the endothelial nitric oxide synthase gene is associated with coronary spasm and acute myocardial infarction.
|
12243851 |
2002 |
|
Adenocarcinoma of lung (disorder)
|
|
0.010 |
GeneticVariation
|
BEFREE |
In conclusion, our study showed that <i>eNOS</i> 894 G/T variants were significantly associated with EGFR mutation types of lung adenocarcinoma, specifically exon 19 in-frame deletion.
|
30026850 |
2018 |
|
Age related macular degeneration
|
|
0.010 |
GeneticVariation
|
BEFREE |
The results obtained in our study suggest a potential role of the rs1800566, rs1799983 and rs6726395 polymorphisms in the AMD pathogenesis.
|
23276910 |
2013 |
|
Aggressive periodontitis, generalized
|
|
0.010 |
GeneticVariation
|
BEFREE |
The present study showed that eNOS Glu298Asp polymorphism is associated with BOP in GAgP patients.
|
16881803 |
2006 |
|
Alcohol abuse
|
|
0.010 |
GeneticVariation
|
BEFREE |
Genomic DNA from 103 patients with nontraumatic FHON (idiopathic in 50, steroid-induced in 29, and alcohol abuse in 24) and 103 control subjects matched for gender and age (3-year range) was analyzed for the 27-bp repeat polymorphism in intron 4 and Glu298Asp polymorphism in exon 7.
|
16779830 |
2006 |
|
Allergic asthma
|
|
0.010 |
GeneticVariation
|
BEFREE |
This study investigated associations of 27 base-pair tandem repeat polymorphism in intron 4 and the Glu298Asp (G894T) variant of the NOS3 gene with atopic asthma in a Czech population.
|
12190658 |
2002 |
|
Alzheimer disease, familial, type 3
|
|
0.010 |
GeneticVariation
|
BEFREE |
Influence of the Glu298Asp polymorphism of NOS3 on age at onset and homocysteine levels in AD patients.
|
15718036 |
2005 |
|
Alzheimer Disease, Late Onset
|
|
0.030 |
GeneticVariation
|
BEFREE |
Recently a significant association of a missense mutation (Glu298Asp) of the endothelial nitric oxide synthase (NOS3) gene with late-onset Alzheimer's disease (LOAD) was reported.
|
11041283 |
2000 |
|
Alzheimer Disease, Late Onset
|
|
0.030 |
GeneticVariation
|
BEFREE |
Association between NOS3 gene G894T polymorphism and late-onset Alzheimer disease in a sample from Iran.
|
20505439 |
2010 |
|
Alzheimer Disease, Late Onset
|
|
0.030 |
GeneticVariation
|
BEFREE |
These results suggest that the NOS3 gene Glu298Asp polymorphism might be a risk factor for LOAD and dependent on APOE epsilon 4 status in Chinese.
|
18183499 |
2008 |
|
Alzheimer's Disease
|
|
0.080 |
GeneticVariation
|
BEFREE |
This meta-analysis suggested that the NOS3 Glu298Asp gene polymorphism is not a strong risk factor for AD.
|
23952620 |
2014 |
|
Alzheimer's Disease
|
|
0.080 |
GeneticVariation
|
BEFREE |
Influence of the Glu298Asp polymorphism of NOS3 on age at onset and homocysteine levels in AD patients.
|
15718036 |
2005 |
|
Alzheimer's Disease
|
|
0.080 |
GeneticVariation
|
BEFREE |
No association between Glu298Asp endothelial nitric oxide synthase polymorphism and Italian sporadic Alzheimer's disease.
|
12697290 |
2003 |
|
Alzheimer's Disease
|
|
0.080 |
GeneticVariation
|
BEFREE |
Association between Alzheimer's disease and the NOS3 gene Glu298Asp polymorphism in Chinese.
|
18183499 |
2008 |
|
Alzheimer's Disease
|
|
0.080 |
GeneticVariation
|
BEFREE |
The meta-analysis showed a small effect of the Glu298Asp</span> GG genotype on AD risk across all studies (summary odds ratio = 1.15, 95% confidence interval: 0.97-1.35) and significant heterogeneity of this association among studies (p = 0.02).
|
16813604 |
2006 |