|
Secondary malignant neoplasm of lymph node
|
|
0.010 |
GeneticVariation
|
BEFREE |
In conclusion, although eNOS SNPs rs2070744 and rs1799983 do not display significant associations with cervical carcinogenesis and patient survival, cervical cancer patients with genotypes TC/CC in rs2070744 carry less risk of advanced stage, parametrium invasion and pelvic lymph node metastasis in Taiwan.
|
31258766 |
2019 |
|
Nasopharyngeal carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
NOS3 G894T was associated with NPC risk.
|
30758659 |
2019 |
|
Sleep Apnea, Obstructive
|
|
0.010 |
GeneticVariation
|
BEFREE |
Results showed there was no association between rs841, A930G p22phox and rs1799983 polymorphism and the risk of OSA (P = 0.51, P = 0.4 and P = 0.33, respectively).
|
31819149 |
2019 |
|
Left-Sided Heart Failure
|
|
0.010 |
GeneticVariation
|
BEFREE |
In patients with HF-PH, the NOS3 rs1</span>799983 polymorphism is associated with TPG, and potentially mPAP and DPG as well.
|
29718770 |
2019 |
|
Carcinogenesis
|
|
0.010 |
GeneticVariation
|
BEFREE |
In conclusion, although eNOS SNPs rs2070744 and rs1799983 do not display significant associations with cervical carcinogenesis and patient survival, cervical cancer patients with genotypes TC/CC in rs2070744 carry less risk of advanced stage, parametrium invasion and pelvic lymph node metastasis in Taiwan.
|
31258766 |
2019 |
|
Kidney Calculi
|
|
0.010 |
GeneticVariation
|
BEFREE |
The endothelial nitric oxide synthase gene G894T, glutathione S-transferase (GSTM1 and GSTT1) polymorphisms as a risk factor in the patient with nephrolithiasis.
|
31445152 |
2019 |
|
Nephrolithiasis
|
|
0.010 |
GeneticVariation
|
BEFREE |
The endothelial nitric oxide synthase gene G894T, glutathione S-transferase (GSTM1 and GSTT1) polymorphisms as a risk factor in the patient with nephrolithiasis.
|
31445152 |
2019 |
|
Dengue Fever
|
|
0.010 |
GeneticVariation
|
BEFREE |
For the ENOS (rs1799983) SNP, the genotype GT was positively associated with protection for development of the clinical form in DHF compared to dengue fever (OR = 0.39, 95% CI = (0.13-1.14), p = 0.0058) in codominant GG/GT/TT and overdominant model GT vs GG + TT (OR = 0.35, 95% CI = (0.12-1.02), p = 0.04).
|
30452889 |
2019 |
|
Ataxia with vitamin E deficiency
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our study gave a comprehensive insight into functional interaction between GNB3 and eNOS gene polymorphisms and suggests that the eNOS G894T and T-786C variants are strong predisposing factors of VED susceptibility within men with type 2 diabetes.
|
30101547 |
2018 |
|
Carcinoma of urinary bladder, invasive
|
|
0.010 |
GeneticVariation
|
BEFREE |
We adjusted for the EORTC score and found that 2 SNPs, NOS3 895G>T (rs1799983) (p = 0.02, HR = 4.32, 95% CI, 1.30-14.39, GT+TT vs. GG) and CBR3 730G>A (rs1056892) (p = 0.04, HR = 2.57, 95% CI, 1.07-6.18, GA+AA vs. GG), were significantly associated with a higher recurrence risk after TUR and instillations of THP in NMIBC patients.
|
30125887 |
2018 |
|
Tumor Cell Invasion
|
|
0.010 |
GeneticVariation
|
BEFREE |
With the subgroup of EGFR L858R mutation, variant genotypes (GT + TT) of <i>eNOS</i> 894 G/T were significantly associated with lymph node invasion.
|
30026850 |
2018 |
|
Oligoasthenozoospermia
|
|
0.010 |
GeneticVariation
|
BEFREE |
The aim of this study was to assess the possible association of three genetic variants (rs2070744, rs1799983 and intron variant 4a/4b) in NOS3 gene and infertility occurrence in two groups of infertile men (idiopathic azoospermia and oligoasthenozoospermia) and fertile controls.
|
28466478 |
2018 |
|
Spindle cell hemangioma
|
|
0.010 |
GeneticVariation
|
BEFREE |
The goal of this study was to evaluate whether genetic variants T-786C (rs2070744), G894T (rs1799983) and C774T (rs1549758) in the endothelial nitric oxide (NOS3) gene and/or their haplotypes could be associated with the risk of MetS in SCH patients or healthy subjects from Russian population.
|
29907847 |
2018 |
|
Peripheral Arterial Diseases
|
|
0.010 |
GeneticVariation
|
BEFREE |
In addition, we also found that the rs1799983 polymorphism was significantly associated with the susceptibility to peripheral artery disease, whereas the rs2070744 polymorphism was significantly associated with the susceptibility to coronary artery disease in DM patients.
|
30140993 |
2018 |
|
Peripheral arterial stenosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
In addition, we also found that the rs1799983 polymorphism was significantly associated with the susceptibility to peripheral artery disease, whereas the rs2070744 polymorphism was significantly associated with the susceptibility to coronary artery disease in DM patients.
|
30140993 |
2018 |
|
Malignant neoplasm of mouth
|
|
0.010 |
GeneticVariation
|
BEFREE |
Two single-nucleotide polymorphisms (SNPs) of the eNOS gene, -786 T > C (rs2070744) and 894G > T (rs1799983), were genotyped in 1200 controls and 1044 patients with oral cancer using a TaqMan-based real-time polymerase chain reaction (PCR).
|
29932969 |
2018 |
|
Dyslipidemias
|
|
0.010 |
GeneticVariation
|
BEFREE |
The risk also holds for the G894T and T-786C eNOS gene polymorphisms when excluding patients with dyslipidemia and cardiovascular diseases (p = 1.7·10<sup>-4</sup> and p = 3.2·10<sup>-5</sup> , respectively).
|
30101547 |
2018 |
|
Adenocarcinoma of lung (disorder)
|
|
0.010 |
GeneticVariation
|
BEFREE |
In conclusion, our study showed that <i>eNOS</i> 894 G/T variants were significantly associated with EGFR mutation types of lung adenocarcinoma, specifically exon 19 in-frame deletion.
|
30026850 |
2018 |
|
Lip and Oral Cavity Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Two single-nucleotide polymorphisms (SNPs) of the eNOS gene, -786 T > C (rs2070744) and 894G > T (rs1799983), were genotyped in 1200 controls and 1044 patients with oral cancer using a TaqMan-based real-time polymerase chain reaction (PCR).
|
29932969 |
2018 |
|
Mycoplasma pneumonia
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our results showed that 3 SNPs of ACE rs4340, IL-6 rs1800795, and NOS3 rs1799983 were significantly associated with the risks of MPP, while no differences were observed in genotype frequencies of GSTM1 (Ins/del) and CYP1A1 rs2606345 between both groups.
|
28403117 |
2017 |
|
Otitis Media with Effusion
|
|
0.010 |
GeneticVariation
|
BEFREE |
To the best of our knowledge, G allele was identified as predisposing to the development of OME and this is the first report indicates the correlation between the eNOS G894T polymorphism and OME in Turkey.
|
27131733 |
2017 |
|
Liver Cirrhosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
The frequency of GG, GT, and TT genotypes for the eNOS G894T polymorphism in the cirrhosis with ascites group was 55.7%, 38.6%, and 5.7% respectively, while in the stable cirrhosis group these figures were 60.9%, 36.2%, and 2.9%.
|
27906429 |
2016 |
|
Lower Urinary Tract Symptoms
|
|
0.010 |
GeneticVariation
|
BEFREE |
The association of endothelial nitric oxide synthase (eNOS) G894T gene polymorphism with responsiveness to a selective α1 -blocker in men with benign prostatic hyperplasia related lower urinary tract symptoms.
|
26940040 |
2016 |
|
Skin toxicity
|
|
0.010 |
GeneticVariation
|
BEFREE |
A significant association was also observed between NOS3 G894T polymorphism (OR, 9.8; 95% CI, 211.6 to 0.45; p=0.041) and grade ≥ 2 acute radiation skin toxicity in patients with neo-adjuvant chemotherapy treatment.
|
26790968 |
2016 |
|
Prostatism
|
|
0.010 |
GeneticVariation
|
BEFREE |
The parameters assessed included body mass index (BMI), smoking habits, presence of prostatism, prostate-specific antigen (PSA) levels, Gleason scores of prostate specimens, as well as polymorphisms in eNOS-G894T, CAT- 262T, and MPO G-463T genes.
|
27706591 |
2016 |