Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 2494 527
IL6 P05231 interleukin 6 0.32 0.248 0.962 2367 22
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962 1558 50
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 1483 15
ALB P02768 albumin Transporter 0.64 0.317 0.962 1198 21
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923 1110 39
VDR P11473 vitamin D receptor Nuclear receptor 1.7E-05 0.352 0.885 852 81
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885 823 34
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885 877 101
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885 816 119
REN P00797 renin Enzyme 2.4E-07 0.370 0.923 721 25
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885 675 21
GABPA Q06546 GA binding protein transcription factor subunit alpha Transcription factor 1.00 0.379 0.885 632 0
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846 679 23
LMNA P02545 lamin A/C 1.00 0.384 0.885 824 285
PTH P01270 parathyroid hormone 1.2E-02 0.397 0.846 528 10
PRKAR1A P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 1.00 0.401 0.846 597 65
CASR P41180 calcium sensing receptor G-protein coupled receptor 4.7E-02 0.410 0.846 517 131
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885 536 61
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885 450 16
TNFRSF11B O00300 TNF receptor superfamily member 11b 0.16 0.422 0.808 443 30
BMP4 P12644 bone morphogenetic protein 4 Signaling 0.96 0.422 0.808 423 21
BMP2 P12643 bone morphogenetic protein 2 Signaling 0.99 0.432 0.846 428 12
RUNX2 Q13950 RUNX family transcription factor 2 Transcription factor 0.95 0.437 0.846 405 37