Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
IL6 P05231 interleukin 6 0.32 0.248 0.962 2367 22
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 1483 15
LMNA P02545 lamin A/C 1.00 0.384 0.885 824 285
PRKAR1A P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 1.00 0.401 0.846 597 65
PTH P01270 parathyroid hormone 1.2E-02 0.397 0.846 528 10
TNFRSF11B O00300 TNF receptor superfamily member 11b 0.16 0.422 0.808 443 30
ADAM17 P78536 ADAM metallopeptidase domain 17 1.00 0.453 0.808 316 11
BGLAP P02818 bone gamma-carboxyglutamate protein 4.6E-08 0.462 0.846 274 2
SOST Q9BQB4 sclerostin 0.87 0.474 0.808 270 4
PDE4D Q08499 phosphodiesterase 4D 1.00 0.519 0.846 210 68
CEACAM1 P13688 CEA cell adhesion molecule 1 7.9E-04 0.525 0.731 167 0
CYP11B2 P19099 cytochrome P450 family 11 subfamily B member 2 7.1E-19 0.553 0.615 142 27
MIR30B microRNA 30b 0.555 0.808 109 1
KAT8 Q9H7Z6 lysine acetyltransferase 8 0.22 0.592 0.654 80 3
HPT hypoparathyroidism 0.593 0.692 71 0
FAM111A Q96PZ2 family with sequence similarity 111 member A 2.2E-03 0.663 0.462 64 6
GCM2 O75603 glial cells missing transcription factor 2 9.1E-04 0.647 0.538 54 12
SMPD3 Q9NY59 sphingomyelin phosphodiesterase 3 0.59 0.659 0.615 50 8
PTRH1 Q86Y79 peptidyl-tRNA hydrolase 1 homolog 1.7E-04 0.663 0.462 39 0
GNAS-AS1 GNAS antisense RNA 1 0.729 0.346 22 8
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923 1110 39
TBCE Q15813 tubulin folding cofactor E Chaperone 1.7E-08 0.575 0.692 146 15
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885 823 34
REN P00797 renin Enzyme 2.4E-07 0.370 0.923 721 25