Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
MIR30B microRNA 30b 0.555 0.808 109 1
HPT hypoparathyroidism 0.593 0.692 71 0
GNAS-AS1 GNAS antisense RNA 1 0.729 0.346 22 8
RYR1 P21817 ryanodine receptor 1 Ion channel 1.6E-29 0.489 0.808 320 248
CYP24A1 Q07973 cytochrome P450 family 24 subfamily A member 1 Enzyme 3.2E-23 0.518 0.692 171 39
CYP11B2 P19099 cytochrome P450 family 11 subfamily B member 2 7.1E-19 0.553 0.615 142 27
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885 450 16
ZMPSTE24 O75844 zinc metallopeptidase STE24 Enzyme 8.9E-16 0.517 0.731 265 11
WWOX Q9NZC7 WW domain containing oxidoreductase Enzyme 1.2E-15 0.453 0.808 356 58
SHMT1 P34896 serine hydroxymethyltransferase 1 Enzyme 1.3E-14 0.566 0.654 106 12
SLC34A3 Q8N130 solute carrier family 34 member 3 Transporter 5.9E-14 0.695 0.308 58 20
CACNA1S Q13698 calcium voltage-gated channel subunit alpha1 S Ion channel 6.3E-12 0.595 0.692 118 22
SLC34A2 O95436 solute carrier family 34 member 2 Transporter 9.4E-11 0.656 0.423 44 3
COASY Q13057 Coenzyme A synthase Enzyme 8.1E-10 0.551 0.654 125 12
GALNT3 Q14435 polypeptide N-acetylgalactosaminyltransferase 3 Enzyme 7.4E-09 0.603 0.769 80 19
TBCE Q15813 tubulin folding cofactor E Chaperone 1.7E-08 0.575 0.692 146 15
BGLAP P02818 bone gamma-carboxyglutamate protein 4.6E-08 0.462 0.846 274 2
CYP27B1 O15528 cytochrome P450 family 27 subfamily B member 1 Enzyme 1.9E-07 0.502 0.769 229 27
REN P00797 renin Enzyme 2.4E-07 0.370 0.923 721 25
ADH1B P00325 alcohol dehydrogenase 1B (class I), beta polypeptide Enzyme 9.9E-07 0.502 0.846 224 30
VDR P11473 vitamin D receptor Nuclear receptor 1.7E-05 0.352 0.885 852 81
ILK Q13418 integrin linked kinase Kinase 3.8E-05 0.503 0.769 192 0
PTRH1 Q86Y79 peptidyl-tRNA hydrolase 1 homolog 1.7E-04 0.663 0.462 39 0
KL Q9UEF7 klotho Enzyme 2.2E-04 0.448 0.769 332 20