Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 2494 527
IL6 P05231 interleukin 6 0.32 0.248 0.962 2367 22
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962 1558 50
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 1483 15
ALB P02768 albumin Transporter 0.64 0.317 0.962 1198 21
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923 1110 39
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885 877 101
VDR P11473 vitamin D receptor Nuclear receptor 1.7E-05 0.352 0.885 852 81
LMNA P02545 lamin A/C 1.00 0.384 0.885 824 285
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885 823 34
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885 816 119
REN P00797 renin Enzyme 2.4E-07 0.370 0.923 721 25
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846 679 23
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885 675 21
GABPA Q06546 GA binding protein transcription factor subunit alpha Transcription factor 1.00 0.379 0.885 632 0
PRKAR1A P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 1.00 0.401 0.846 597 65
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885 536 61
PTH P01270 parathyroid hormone 1.2E-02 0.397 0.846 528 10
CASR P41180 calcium sensing receptor G-protein coupled receptor 4.7E-02 0.410 0.846 517 131
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885 450 16
TNFRSF11B O00300 TNF receptor superfamily member 11b 0.16 0.422 0.808 443 30
BMP2 P12643 bone morphogenetic protein 2 Signaling 0.99 0.432 0.846 428 12
BMP4 P12644 bone morphogenetic protein 4 Signaling 0.96 0.422 0.808 423 21
RUNX2 Q13950 RUNX family transcription factor 2 Transcription factor 0.95 0.437 0.846 405 37