Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
TNFRSF1A P19438 TNF receptor superfamily member 1A 0.99 0.409 0.923 26
ANGPT2 O15123 angiopoietin 2 Signaling 0.83 0.410 0.846 25
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846 25
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923 25
CASP12 Q6UXS9 caspase 12 (gene/pseudogene) 1.3E-04 0.638 0.808 23
S100B P04271 S100 calcium binding protein B Calcium-binding protein 4.4E-02 0.383 0.923 23
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885 22
CTSB P07858 cathepsin B Enzyme 5.9E-11 0.457 0.846 22
FASLG P48023 Fas ligand Signaling 0.18 0.430 0.885 22
AQP4 P55087 aquaporin 4 Ion channel 2.3E-03 0.456 0.885 21
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885 20
SCN5A Q14524 sodium voltage-gated channel alpha subunit 5 Ion channel 0.91 0.513 0.654 20
TH P07101 tyrosine hydroxylase 1.7E-06 0.462 0.885 18
AIF1 P55008 allograft inflammatory factor 1 Calcium-binding protein 1.9E-06 0.521 0.808 17
BCL2L1 Q07817 BCL2 like 1 Signaling 0.94 0.493 0.885 17
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808 17
EPOR P19235 erythropoietin receptor Receptor 1.0E-02 0.526 0.692 17
MMP13 P45452 matrix metallopeptidase 13 Enzyme 7.9E-18 0.452 0.923 17
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846 17
IL6ST P40189 interleukin 6 signal transducer Signaling 1.00 0.475 0.808 16
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923 16
PLA2G4A P47712 phospholipase A2 group IVA Enzyme 6.0E-05 0.496 0.846 16
LGALS3 P17931 galectin 3 Signaling 2.3E-05 0.392 0.846 15
ALOX5 P09917 arachidonate 5-lipoxygenase Enzyme 1.2E-06 0.447 0.885 14