×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
melanoma
0.800
Biomarker
CTD_human
Genetic alterations driving metastatic colony formation are acquired outside of the primary tumour in melanoma.
29426936
2018
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Pancreatic Neoplasm
0.800
Biomarker
CTD_human
Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer.
26098869
2015
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
melanoma
0.800
Biomarker
CTD_human
In 47 melanoma cell lines homozygous loss, methylation or mutation of CDKN2A gene or loss of protein (p16(INK) (4A) ) predicted sensitivity to the CDK4/6 inhibitor PD0332991, while RB1 loss predicted resistance.
24495407
2014
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Lung Neoplasms
0.800
Biomarker
CTD_human
Implication of p16 inactivation in tumorigenic activity of respiratory epithelial cell lines and adenocarcinoma cell line established from plutonium-induced lung tumor in rat.
20135361
2010
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Esophageal Neoplasms
0.800
Biomarker
CTD_human
Progressive silencing of p14ARF in oesophageal adenocarcinoma.
18410530
2009
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Lung Neoplasms
0.800
Biomarker
CTD_human
DNA methylation markers and early recurrence in stage I lung cancer.
18337602
2008
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Lung Neoplasms
0.800
Biomarker
CTD_human
Aberrant methylation of the CDKN2a/p16INK4a gene promoter region in preinvasive bronchial lesions: a prospective study in high-risk patients without invasive cancer.
12115568
2002
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Lung Neoplasms
0.800
Biomarker
CTD_human
Methylation of the p16 and ER genes was very common (80 and 50%, respectively) in beryllium-induced lung tumors ; both genes were methylated in 40% of the tumors.
11872642
2002
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Pancreatic Neoplasm
0.800
Biomarker
CTD_human
Novel germline p16(INK4) allele (Asp145Cys) in a family with multiple pancreatic carcinomas. Mutations in brief no. 148. Online.
10627132
1998
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Esophageal Neoplasms
0.800
GeneticVariation
UNIPROT
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Lung Neoplasms
0.800
GeneticVariation
UNIPROT
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
melanoma
0.800
GeneticVariation
UNIPROT
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
melanoma
0.800
GenomicAlterations
CGI
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
melanoma
0.800
CausalMutation
CGI
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
melanoma
0.800
Biomarker
GENOMICS_ENGLAND
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Pancreatic Neoplasm
0.800
GeneticVariation
UNIPROT
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Pancreatic Neoplasm
0.800
GenomicAlterations
CGI
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Pancreatic Neoplasm
0.800
CausalMutation
CGI
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Liver carcinoma
0.700
Biomarker
CTD_human
Computational Discovery of Niclosamide Ethanolamine, a Repurposed Drug Candidate That Reduces Growth of Hepatocellular Carcinoma Cells In Vitro and in Mice by Inhibiting Cell Division Cycle 37 Signaling.
28284560
2017
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Liver carcinoma
0.700
Biomarker
CTD_human
Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets.
25822088
2015
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Squamous cell carcinoma
0.700
Biomarker
CTD_human
Functional kinomics identifies candidate therapeutic targets in head and neck cancer.
25125259
2014
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Cutaneous Melanoma
0.700
Biomarker
CTD_human
A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma.
22080950
2011
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 2
0.700
Biomarker
GENOMICS_ENGLAND
Novel and recurrent p14 mutations in Italian familial melanoma.
20132244
2010
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 2
0.700
GeneticVariation
UNIPROT
Functional, structural, and genetic evaluation of 20 CDKN2A germ line mutations identified in melanoma-prone families or patients.
19260062
2009
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 2
0.700
GeneticVariation
UNIPROT
A novel L94Q mutation in the CDKN2A gene in a melanoma kindred.
14646619
2003