|
rs1010
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This result suggests that rs1010 genotyping could be used as prognostic biomarker to predict the risk of Mtb infection and/or PTB disease development after Mtb infection in the Chinese Han population.
|
30945947 |
2019 |
|
rs10759932
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genetic polymorphisms of rs10759932 and rs2737190 in TLR4 are significantly related to both COPD and PTB but with inverse effects.
|
31640653 |
2019 |
|
rs10841845
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our findings suggest that variations at rs10841845 and rs10841847 of CLEC4E genes are associated with increased individual protection against PTB.
|
31075410 |
2019 |
|
rs10841847
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our findings suggest that variations at rs10841845 and rs10841847 of CLEC4E genes are associated with increased individual protection against PTB.
|
31075410 |
2019 |
|
rs15493
|
|
|
0.010 |
GeneticVariation |
BEFREE |
However, the <i>VTI1B</i> rs15493 SNP had no impact on the susceptibility to PTB (<i>p</i> > 0.05).
|
30945947 |
2019 |
|
rs1927906
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Furthermore, SNPs TLR9 rs352139 and TLR8 rs3764880 were associated with PTB in the late-onset (≥39-year-old) patient group (OR = 0.60, p = 0.0029 and OR = 0.70, p = 0.021, respectively) and SNPs TLR2 rs3804099, TLR4 rs4986790 and TLR4 rs1927906 in the early-onset (≤ 38-year-old) group (OR = 0.53, p = 0.0012; OR = 3.45, p = 0.013; OR = 2.31, p = 0.044, respectively).
|
30529560 |
2019 |
|
rs2228570
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Vitamin D receptor ApaI (rs7975232), BsmI (rs1544410), Fok1 (rs2228570), and TaqI (rs731236) gene polymorphisms and susceptibility to pulmonary tuberculosis in an Iranian population: A systematic review and meta-analysis.
|
31740220 |
2019 |
|
rs2367707
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs2367707 polymorphism was associated with a higher risk of PTB and EPTB (P = 0.00051, P = 0.0012).
|
30634928 |
2019 |
|
rs2737190
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genetic polymorphisms of rs10759932 and rs2737190 in TLR4 are significantly related to both COPD and PTB but with inverse effects.
|
31640653 |
2019 |
|
rs4988453
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SNPs TLR9 rs352139, TLR2 rs3804099 and MYD88 rs4988453 were associated with PTB in females (OR = 0.49, p = 0.0009; OR = 0.51, p = 0.0008; OR = 0.33, p = 0.027; here and below log-additive model with minor alleles assumed as effect associated alleles), while SNP TLR8 rs3764880 showed a significant association in males (OR = 0.44, p = 0.0087).
|
30529560 |
2019 |
|
rs549908
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Reduced secretion of IL-18 and IL-27 by mDCs in PTB patients was associated with 105A/C polymorphisms of the IL18 gene, and 2905T/G, 4730T/С, and -964A/G of the IL27 gene, respectively.
|
30948177 |
2019 |
|
rs731236
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Vitamin D receptor ApaI (rs7975232), BsmI (rs1544410), Fok1 (rs2228570), and TaqI (rs731236) gene polymorphisms and susceptibility to pulmonary tuberculosis in an Iranian population: A systematic review and meta-analysis.
|
31740220 |
2019 |
|
rs7975232
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Vitamin D receptor ApaI (rs7975232), BsmI (rs1544410), Fok1 (rs2228570), and TaqI (rs731236) gene polymorphisms and susceptibility to pulmonary tuberculosis in an Iranian population: A systematic review and meta-analysis.
|
31740220 |
2019 |
|
rs1518111
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found correlations between one SNP in IL6 (rs2069837 <i>p</i> = 6.63E-11), seven SNPs in <i>IL10</i> (rs1554286 <i>p</i> = 6.87E-20, rs1518111 <i>p</i> = 6.11E-11, rs3021094 <i>p</i> = 6.75E-29, rs3790622 <i>p</i> = 2.40E-06, rs3024490 <i>p</i> = 6.73E-11, rs1800872 <i>p</i> = 6.18E-11, rs1800871 <i>p</i> = 6.73E-11) and incidences of PTB.
|
29662655 |
2018 |
|
rs1554286
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found correlations between one SNP in IL6 (rs2069837 <i>p</i> = 6.63E-11), seven SNPs in <i>IL10</i> (rs1554286 <i>p</i> = 6.87E-20, rs1518111 <i>p</i> = 6.11E-11, rs3021094 <i>p</i> = 6.75E-29, rs3790622 <i>p</i> = 2.40E-06, rs3024490 <i>p</i> = 6.73E-11, rs1800872 <i>p</i> = 6.18E-11, rs1800871 <i>p</i> = 6.73E-11) and incidences of PTB.
|
29662655 |
2018 |
|
rs2069837
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found correlations between one SNP in IL6 (rs2069837 <i>p</i> = 6.63E-11), seven SNPs in <i>IL10</i> (rs1554286 <i>p</i> = 6.87E-20, rs1518111 <i>p</i> = 6.11E-11, rs3021094 <i>p</i> = 6.75E-29, rs3790622 <i>p</i> = 2.40E-06, rs3024490 <i>p</i> = 6.73E-11, rs1800872 <i>p</i> = 6.18E-11, rs1800871 <i>p</i> = 6.73E-11) and incidences of PTB.
|
29662655 |
2018 |
|
rs2280789
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Regulatory role of CCL5 (rs2280789) and CXCL10 (rs56061981) gene polymorphisms on intracellular CCL5 and CXCL10 expression in pulmonary tuberculosis.
|
28336310 |
2018 |
|
rs3021094
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The SNPs rs3021094 and rs3790622 decreased PTB risk by 0.33-fold and 0.38-fold, respectively.
|
29662655 |
2018 |
|
rs3024490
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found correlations between one SNP in IL6 (rs2069837 <i>p</i> = 6.63E-11), seven SNPs in <i>IL10</i> (rs1554286 <i>p</i> = 6.87E-20, rs1518111 <i>p</i> = 6.11E-11, rs3021094 <i>p</i> = 6.75E-29, rs3790622 <i>p</i> = 2.40E-06, rs3024490 <i>p</i> = 6.73E-11, rs1800872 <i>p</i> = 6.18E-11, rs1800871 <i>p</i> = 6.73E-11) and incidences of PTB.
|
29662655 |
2018 |
|
rs352140
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genotyping was performed to detect -196 to -174 del polymorphism and G2258A SNP (Arg753Gln, rs5743708) in TLR2 gene and -T1237C (rs5743836) and G2848A (rs352140) SNP in TLR9 gene in patients with pulmonary TB and healthy controls.
|
29675696 |
2018 |
|
rs3774275
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, our results demonstrate a significant association of <i>MASP1</i> polymorphism rs3774275 and MASP1 serum levels with the development of pulmonary TB.
|
29515573 |
2018 |
|
rs3790622
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The SNPs rs3021094 and rs3790622 decreased PTB risk by 0.33-fold and 0.38-fold, respectively.
|
29662655 |
2018 |
|
rs56061981
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Regulatory role of CCL5 (rs2280789) and CXCL10 (rs56061981) gene polymorphisms on intracellular CCL5 and CXCL10 expression in pulmonary tuberculosis.
|
28336310 |
2018 |
|
rs5743836
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genotyping was performed to detect -196 to -174 del polymorphism and G2258A SNP (Arg753Gln, rs5743708) in TLR2 gene and -T1237C (rs5743836) and G2848A (rs352140) SNP in TLR9 gene in patients with pulmonary TB and healthy controls.
|
29675696 |
2018 |
|
rs5743867
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Moreover, rs5743867 under addictive (p = 0.005, OR = 1.54, 95% CI: 1.14-2.07) and recessive model (p = 0.004, OR = 1.86, 95% CI: 1.22-2.83) were also risk factors for PTB susceptibility.
|
29924447 |
2018 |