|
rs10065172
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In contrast, neither PTB nor STB were found to be associated with rs10065172 and rs11003125.
|
28867622 |
2017 |
|
rs1010
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This result suggests that rs1010 genotyping could be used as prognostic biomarker to predict the risk of Mtb infection and/or PTB disease development after Mtb infection in the Chinese Han population.
|
30945947 |
2019 |
|
rs10208770
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two of these SNPs were associated with pulmonary TB (rs10208770 and rs16826860) and one with extra-pulmonary TB (rs10498244).
|
25006821 |
2014 |
|
rs1041981
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The TA haplotype was significantly over-represented (P=0.011) in the cases showing a two-fold risk in the current population (Odds ratio=1.59 CI=1.101 to 2.297) and TNFB variants at rs2229094 and rs1041981 contributed to two haplotypes which were in strong linkage disequilibrium (LD) with AT haplotype showing a three-fold risk (P=0.0011, Odds ratio=3, CI=0.1939 to 0.7445) of developing PTB in north Indians.
|
22771610 |
2012 |
|
rs10421768
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our findings indicate that the HAMP-P -582 A>G polymorphism (rs10421768) is associated with susceptibility to extrapulmonary TB, but not pulmonary TB.
|
28530443 |
2017 |
|
rs1042713
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genotype distributions of the rs1042713 (Arg16Gly +46A>G) and rs1042714 (Gln27Glu +79C>G) polymorphisms in ADRB2 gene in 106 patients with pulmonary tuberculosis and 88 healthy subjects were studied by PCR-RFLP method in an Iranian population.
|
27900465 |
2017 |
|
rs1042714
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genotype distributions of the rs1042713 (Arg16Gly +46A>G) and rs1042714 (Gln27Glu +79C>G) polymorphisms in ADRB2 gene in 106 patients with pulmonary tuberculosis and 88 healthy subjects were studied by PCR-RFLP method in an Iranian population.
|
27900465 |
2017 |
|
rs10498244
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two of these SNPs were associated with pulmonary TB (rs10208770 and rs16826860) and one with extra-pulmonary TB (rs10498244).
|
25006821 |
2014 |
|
rs10499859
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These data showed that MARCO rs12998782 may increase PTB risk while two SNPs of CD36, rs1194182 and rs10499859 may reduce the risk, indicating MARCO and CD36 as important receptors in response to PTB.
|
28693442 |
2017 |
|
rs1050504
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Only the rs1050504 C > T genotype was observed to be significantly associated with an increased risk for developing pulmonary TB (41.8% vs 27%, OR 1.95, 95% CI 1.16-3.27; p = 0.01).
|
29115933 |
2017 |
|
rs1057141
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No significant association was found between TAP1 (rs1057141), TAP2 (rs2228396, rs67511411, rs141555015) variants and PTB.
|
26996113 |
2016 |
|
rs10759931
|
|
|
0.010 |
GeneticVariation |
BEFREE |
An MDR analysis of gene-gene and gene-environment interactions identified three SNPs (rs10759932, rs7873784, and rs10759931) that predicted LTBI with 84% accuracy (p = 0.0004) and three SNPs (rs3804100, rs1898830, and rs10759931) that predicted PTB with 80% accuracy (p = 0.0001).
|
25928077 |
2015 |
|
rs10759932
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genetic polymorphisms of rs10759932 and rs2737190 in TLR4 are significantly related to both COPD and PTB but with inverse effects.
|
31640653 |
2019 |
|
rs10841845
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our findings suggest that variations at rs10841845 and rs10841847 of CLEC4E genes are associated with increased individual protection against PTB.
|
31075410 |
2019 |
|
rs10841847
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our findings suggest that variations at rs10841845 and rs10841847 of CLEC4E genes are associated with increased individual protection against PTB.
|
31075410 |
2019 |
|
rs10995271
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In this study, we identified an association with borderline significance (P = 0.0009433 and P = 0.029 after multiple testing by Bonferroni's correction) of SNP rs10995271 with PTB.
|
24365559 |
2014 |
|
rs11003125
|
|
|
0.020 |
GeneticVariation |
BEFREE |
However, the other genetic models of rs1800450 (A>B), rs7096206 (Y>X), and rs11003125 (H>L) MBL2 gene polymorphisms did not divulge any association with PTB susceptibility.
|
30666135 |
2019 |
|
rs11003125
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In contrast, neither PTB nor STB were found to be associated with rs10065172 and rs11003125.
|
28867622 |
2017 |
|
rs11168287
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The goal of this study was the identification of putative associations between five SNPs (rs11574143, rs7975232, rs11574079, rs3819545 and rs11168287) in VDR and susceptibility to PTB.
|
27595605 |
2016 |
|
rs11209026
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results demonstrate that the reduced-function polymorphism 1142G → A encoded by IL23R influences the outcome of disease severity of active pulmonary TB in Tunisian patients.
|
22695161 |
2012 |
|
rs1135216
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs1135216 G allele was associated with increased risk of PTB (OR=2.65, 95%CI=1.784-3.969, p<0.001).
|
26996113 |
2016 |
|
rs1135791
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The <i>TNF-α</i> -238 A allele appeared a protective effect against STB, whereas the <i>SP110</i> SNPs (rs722555 and rs1135791) and <i>TNF-α</i> -308G>A (rs1800629) showed no association with susceptibility to PTB and STB patients in southern China.
|
29430075 |
2017 |
|
rs1136452
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This polymorphism, when existing along with a non-redundant polymorphism, SP-A2G1649C (Ala91Pro) resulted in a stronger association with pulmonary tuberculosis (number of patients = 17, number of controls = 19, p = 0.000, OR = 16.3, 95% CI: 7.8644<OR<33.9244).
|
12476938 |
2002 |
|
rs11568350
|
|
|
0.010 |
GeneticVariation |
BEFREE |
There was significantly higher prevalence of pulmonary TB (P = 0.01) and Pneumocystis jiroveci pneumonia (P = 0.02) in subjects with ferroportin Q248H mutation.
|
22249207 |
2012 |
|
rs11574079
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The goal of this study was the identification of putative associations between five SNPs (rs11574143, rs7975232, rs11574079, rs3819545 and rs11168287) in VDR and susceptibility to PTB.
|
27595605 |
2016 |