|
rs1800896
|
|
|
0.020 |
GeneticVariation |
BEFREE |
<i>IL-10</i> -1082 A>G (rs1800896) polymorphism confers susceptibility to pulmonary tuberculosis in Caucasians but not in Asians and Africans: a meta-analysis.
|
28951522 |
2017 |
|
rs5743708
|
|
|
0.080 |
GeneticVariation |
BEFREE |
(3) Stratified by sample type, TLR2 Arg753Gln polymorphism is associated with increased PTB risk, but not with EPTB.
|
30733958 |
2019 |
|
rs2476601
|
|
|
0.040 |
GeneticVariation |
BEFREE |
R620W functional polymorphism of protein tyrosine phosphatase non-receptor type 22 is not associated with pulmonary tuberculosis in Zahedan, southeast Iran.
|
22614276 |
2012 |
|
rs5743618
|
|
|
0.040 |
GeneticVariation |
BEFREE |
T1805G, a functional TLR1 single nucleotide polymorphism (SNP), has been associated with susceptibility to pulmonary tuberculosis (PTB), but contradictory results among different populations have been reported.
|
23575331 |
2013 |
|
rs5743708
|
|
|
0.080 |
GeneticVariation |
BEFREE |
A meta-analysis was conducted to investigate the relationship between TLR2 G2</span>258A and T597C polymorphisms with PTB susceptibility.
|
24124467 |
2013 |
|
rs2910164
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A polymorphism (rs2910164 G>C) indicated an association with PTB risk in both Tibetan (p = 0.031) and Han (p = 0.000) populations.
|
21524676 |
2011 |
|
rs1544410
|
|
|
0.020 |
GeneticVariation |
BEFREE |
A reappraised meta-analysis of the genetic association between vitamin D receptor <i>Bsm</i>I (rs1544410) polymorphism and pulmonary tuberculosis risk.
|
28533426 |
2017 |
|
rs370738284
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A trend towards an increased frequency of TT genotype of TIRAP 975C/T was also observed in PTB patients [p = 0.078, OR 3.10 95% CI (0.96-10.05)].
|
20797905 |
2010 |
|
rs5917471
|
|
|
0.010 |
GeneticVariation |
BEFREE |
After adjusting for confounders including age, gender and smoking, rs5917471 allele T showed significant association with decreased risk of TB (OR 0.745, 95% CI 0.556-0.999) and pulmonary TB (OR 0.618, 95% CI 0.410-0.931).
|
25929165 |
2015 |
|
rs606231248
|
|
|
0.020 |
GeneticVariation |
BEFREE |
After adjustment for age and gender, G1186A sites were found to be dominant (P < 0.01; OR = 0.59; 95% CI, 0.40-0.87), over-dominant (P = 0.045; OR = 0.69; 95% CI, 0.47-0.99) and additive models (P = 0.041; OR = 0.76; 95% CI, 0.59-0.99) in association with pulmonary tuberculosis.
|
22393309 |
2012 |
|
rs10759931
|
|
|
0.010 |
GeneticVariation |
BEFREE |
An MDR analysis of gene-gene and gene-environment interactions identified three SNPs (rs10759932, rs7873784, and rs10759931) that predicted LTBI with 84% accuracy (p = 0.0004) and three SNPs (rs3804100, rs1898830, and rs10759931) that predicted PTB with 80% accuracy (p = 0.0001).
|
25928077 |
2015 |
|
rs1800451
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Assuming a recessive mode of inheritance, we found a protective association between TB and the MBL2 G57E variant (odds ratio 0.60, confidence interval 0.4-0.9, P 0.008) and the corresponding LYQC haplotype (P(corrected) 0.007) which applied, however, only to TB caused by M. africanum but not to TB caused by M. tuberculosis.
|
21695215 |
2011 |
|
rs4986790
|
|
|
0.060 |
GeneticVariation |
BEFREE |
BACKGROUND Findings regarding the association of the single-nucleotide polymorphisms (SNPs) rs4986790 and rs4986791 in Toll-like receptor 4 and rs187084, rs574386, and rs352139 in Toll-like receptor 9 (TLR9) with pulmonary tuberculosis (PTB) susceptibility are inconsistent.
|
25889916 |
2015 |
|
rs187084
|
|
|
0.030 |
GeneticVariation |
BEFREE |
BACKGROUND Findings regarding the association of the single-nucleotide polymorphisms (SNPs) rs4986790 and rs4986791 in Toll-like receptor 4 and rs187084, rs574386, and rs352139 in Toll-like receptor 9 (TLR9) with pulmonary tuberculosis (PTB) susceptibility are inconsistent.
|
25889916 |
2015 |
|
rs574386
|
|
|
0.010 |
GeneticVariation |
BEFREE |
BACKGROUND Findings regarding the association of the single-nucleotide polymorphisms (SNPs) rs4986790 and rs4986791 in Toll-like receptor 4 and rs187084, rs574386, and rs352139 in Toll-like receptor 9 (TLR9) with pulmonary tuberculosis (PTB) susceptibility are inconsistent.
|
25889916 |
2015 |
|
rs1800629
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Based upon the functional role of the TNF-α [-308 G(low) → A(high) (rs1800629)] and IL-10 [-1082 A(low) → G(high) (rs1800870), -819 T(low) → C(high) (rs1800871) and -592 A(low) → C(high) (rs1800872)] single nucleotide polymorphisms (SNPs) on production levels, we genotyped 76 patients with pulmonary tuberculosis (TB) (pTB), 55 patients with extrapulmonary TB (epTB) and 95 healthy blood donors by polymerase chain reaction fragment length polymorphism (PCR-RFLP).
|
21609779 |
2011 |
|
rs1800870
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Based upon the functional role of the TNF-α [-308 G(low) → A(high) (rs1800629)] and IL-10 [-1082 A(low) → G(high) (rs1800870), -819 T(low) → C(high) (rs1800871) and -592 A(low) → C(high) (rs1800872)] single nucleotide polymorphisms (SNPs) on production levels, we genotyped 76 patients with pulmonary tuberculosis (TB) (pTB), 55 patients with extrapulmonary TB (epTB) and 95 healthy blood donors by polymerase chain reaction fragment length polymorphism (PCR-RFLP).
|
21609779 |
2011 |
|
rs1800871
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Based upon the functional role of the TNF-α [-308 G(low) → A(high) (rs1800629)] and IL-10 [-1082 A(low) → G(high) (rs1800870), -819 T(low) → C(high) (rs1800871) and -592 A(low) → C(high) (rs1800872)] single nucleotide polymorphisms (SNPs) on production levels, we genotyped 76 patients with pulmonary tuberculosis (TB) (pTB), 55 patients with extrapulmonary TB (epTB) and 95 healthy blood donors by polymerase chain reaction fragment length polymorphism (PCR-RFLP).
|
21609779 |
2011 |
|
rs1800872
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Based upon the functional role of the TNF-α [-308 G(low) → A(high) (rs1800629)] and IL-10 [-1082 A(low) → G(high) (rs1800870), -819 T(low) → C(high) (rs1800871) and -592 A(low) → C(high) (rs1800872)] single nucleotide polymorphisms (SNPs) on production levels, we genotyped 76 patients with pulmonary tuberculosis (TB) (pTB), 55 patients with extrapulmonary TB (epTB) and 95 healthy blood donors by polymerase chain reaction fragment length polymorphism (PCR-RFLP).
|
21609779 |
2011 |
|
rs1799864
|
|
|
0.010 |
GeneticVariation |
BEFREE |
CCR2 V64I (G/A), monocyte chemoattractant protein-1 (MCP-1) -2518 A/G, stromal cell derived factor-1alpha; (SDF-1alpha) 3'UTR G/A and DC-SIGN gene polymorphisms were studied by polymerase chain reaction based methods in HIV-1 infected patients without TB (n=151), with pulmonary TB (PTB) (n=81) and extrapulmonary TB (n=31), 155 PTB patients without HIV and 206 healthy controls.
|
19942750 |
2009 |
|
rs373950030
|
|
|
0.010 |
GeneticVariation |
BEFREE |
CCR2 V64I (G/A), monocyte chemoattractant protein-1 (MCP-1) -2518 A/G, stromal cell derived factor-1alpha; (SDF-1alpha) 3'UTR G/A and DC-SIGN gene polymorphisms were studied by polymerase chain reaction based methods in HIV-1 infected patients without TB (n=151), with pulmonary TB (PTB) (n=81) and extrapulmonary TB (n=31), 155 PTB patients without HIV and 206 healthy controls.
|
19942750 |
2009 |
|
rs763059810
|
|
|
0.010 |
GeneticVariation |
BEFREE |
CCR2 V64I (G/A), monocyte chemoattractant protein-1 (MCP-1) -2518 A/G, stromal cell derived factor-1alpha; (SDF-1alpha) 3'UTR G/A and DC-SIGN gene polymorphisms were studied by polymerase chain reaction based methods in HIV-1 infected patients without TB (n=151), with pulmonary TB (PTB) (n=81) and extrapulmonary TB (n=31), 155 PTB patients without HIV and 206 healthy controls.
|
19942750 |
2009 |
|
rs2230424
|
|
|
0.010 |
GeneticVariation |
BEFREE |
CD11c/Arg47Trp polymorphism is not associated with PTB.
|
19237023 |
2009 |
|
rs3092923
|
|
|
0.010 |
GeneticVariation |
BEFREE |
CD40LG rs3092923 and its combined effects with the other two SNPs were associated with an increased risk of pTB only in males.
|
26043172 |
2015 |
|
rs187084
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Collectively, these data suggest that the minor "C" allele at rs187084 locus may be associated with susceptibility to PTB, which may explain the relatively lower PTB rates observed in Baiga tribe members.
|
25248338 |
2014 |