Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 101
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 138
IL6 P05231 interleukin 6 0.32 0.248 0.962 54
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 59
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885 62
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 86
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 45
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 94
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923 27
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923 47
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923 64
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923 11
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923 58
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923 62
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923 32
HMGB1 P09429 high mobility group box 1 Nucleic acid binding 0.82 0.368 0.923 23
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923 49
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 72
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923 31
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846 48
TIMP1 P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 0.50 0.380 0.885 19
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 71
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885 27
PARP1 P09874 poly(ADP-ribose) polymerase 1 3.3E-04 0.389 0.923 12