Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
CHRM4 P08173 cholinergic receptor muscarinic 4 G-protein coupled receptor 0.97 0.821 0.231 2
CHRNA4 P43681 cholinergic receptor nicotinic alpha 4 subunit Ion channel 8.5E-05 0.492 0.808 2
DDR1 Q08345 discoidin domain receptor tyrosine kinase 1 Kinase 4.6E-06 0.497 0.808 2
DIO3 P55073 iodothyronine deiodinase 3 0.62 0.593 0.731 2
MMP8 P22894 matrix metallopeptidase 8 Enzyme 1.1E-24 0.488 0.808 2
P2RX4 Q99571 purinergic receptor P2X 4 Ion channel 5.0E-12 0.547 0.808 2
PPP1CC P36873 protein phosphatase 1 catalytic subunit gamma Enzyme 0.96 0.861 0.154 2
SRI P30626 sorcin 3.5E-10 0.587 0.769 2
CORIN Q9Y5Q5 corin, serine peptidase 6.5E-35 0.695 0.538 3
FXYD1 O00168 FXYD domain containing ion transport regulator 1 Ion channel 0.24 0.682 0.385 3
GNAQ P50148 G protein subunit alpha q Enzyme modulator 0.98 0.516 0.808 3
KCNE1 P15382 potassium voltage-gated channel subfamily E regulatory subunit 1 Ion channel 3.4E-03 0.588 0.615 3
MED1 Q15648 mediator complex subunit 1 1.00 0.573 0.692 3
NCAM1 P13591 neural cell adhesion molecule 1 1.00 0.415 0.885 3
NPTXR O95502 neuronal pentraxin receptor 0.72 0.751 0.423 3
RAC1 P63000 Rac family small GTPase 1 Enzyme modulator 0.76 0.429 0.962 3
ALOX15 P16050 arachidonate 15-lipoxygenase Enzyme 1.1E-23 0.502 0.846 4
CALR P27797 calreticulin Calcium-binding protein 0.89 0.413 0.923 4
LIF P15018 LIF interleukin 6 family cytokine Signaling 0.52 0.483 0.769 4
MDH2 P40926 malate dehydrogenase 2 Enzyme 6.7E-03 0.595 0.731 4
OGT O15294 O-linked N-acetylglucosamine (GlcNAc) transferase 1.00 0.626 0.731 4
SCN8A Q9UQD0 sodium voltage-gated channel alpha subunit 8 Ion channel 1.00 0.510 0.731 4
TNFRSF11B O00300 TNF receptor superfamily member 11b 0.16 0.422 0.808 4
ALOX12 P18054 arachidonate 12-lipoxygenase, 12S type Enzyme 1.4E-15 0.558 0.692 5