Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
ACAN P16112 aggrecan Extracellular structure 1.00 0.528 0.846 7
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923 64
ACE2 Q9BYF1 angiotensin I converting enzyme 2 Enzyme 1.00 0.477 0.769 17
ADAM17 P78536 ADAM metallopeptidase domain 17 1.00 0.453 0.808 9
ADM P35318 adrenomedullin Signaling 4.1E-02 0.436 0.808 21
ADRB1 P08588 adrenoceptor beta 1 G-protein coupled receptor 2.9E-06 0.555 0.769 16
ADRB2 P07550 adrenoceptor beta 2 G-protein coupled receptor 0.53 0.442 0.923 20
ADRB3 P13945 adrenoceptor beta 3 G-protein coupled receptor 2.5E-07 0.533 0.731 6
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923 32
AGTR1 P30556 angiotensin II receptor type 1 G-protein coupled receptor 5.3E-04 0.423 0.846 34
AGTR2 P50052 angiotensin II receptor type 2 G-protein coupled receptor 8.2E-03 0.496 0.808 22
ALOX12 P18054 arachidonate 12-lipoxygenase, 12S type Enzyme 1.4E-15 0.558 0.692 5
ALOX15 P16050 arachidonate 15-lipoxygenase Enzyme 1.1E-23 0.502 0.846 4
APLN Q9ULZ1 apelin 0.46 0.497 0.769 7
ARRB1 P49407 arrestin beta 1 Enzyme modulator 0.99 0.588 0.846 5
ATP2A2 P16615 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 Transporter 1.00 0.529 0.808 15
BAX Q07812 BCL2 associated X, apoptosis regulator Signaling 0.32 0.417 0.885 44
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885 62
BECN1 Q14457 beclin 1 Enzyme modulator 0.94 0.432 0.846 40
BIRC5 O15392 baculoviral IAP repeat containing 5 Enzyme modulator 5.6E-02 0.495 0.731 13
BNIP3 Q12983 BCL2 interacting protein 3 2.0E-05 0.520 0.731 14
CALR P27797 calreticulin Calcium-binding protein 0.89 0.413 0.923 4
CASP12 Q6UXS9 caspase 12 (gene/pseudogene) 1.3E-04 0.638 0.808 23
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923 62