Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 72
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 71
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 59
IL6 P05231 interleukin 6 0.32 0.248 0.962 54
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923 49
NOS1 P29475 nitric oxide synthase 1 1.00 0.408 0.885 46
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 45
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923 27
CASP12 Q6UXS9 caspase 12 (gene/pseudogene) 1.3E-04 0.638 0.808 23
NPPB P16860 natriuretic peptide B 9.9E-06 0.513 0.808 20
SCD O00767 stearoyl-CoA desaturase 0.97 0.490 0.808 19
TH P07101 tyrosine hydroxylase 1.7E-06 0.462 0.885 18
NPPA P01160 natriuretic peptide A 5.5E-04 0.505 0.769 17
ENG P17813 endoglin 1.00 0.446 0.846 14
BNIP3 Q12983 BCL2 interacting protein 3 2.0E-05 0.520 0.731 14
PARP1 P09874 poly(ADP-ribose) polymerase 1 3.3E-04 0.389 0.923 12
CYP11B1 P15538 cytochrome P450 family 11 subfamily B member 1 8.2E-07 0.563 0.615 12
SELP P16109 selectin P 5.0E-32 0.460 0.769 12
MYH6 P13533 myosin heavy chain 6 1.6E-32 0.581 0.615 10
PLN P26678 phospholamban 0.45 0.595 0.577 9
ADAM17 P78536 ADAM metallopeptidase domain 17 1.00 0.453 0.808 9
MYH7 P12883 myosin heavy chain 7 4.2E-16 0.516 0.692 8
APLN Q9ULZ1 apelin 0.46 0.497 0.769 7
MTPN P58546 myotrophin 0.82 0.729 0.346 6