Source: CGI

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
MITF O75030 melanocyte inducing transcription factor 0.98 0.499 0.808 2
PAK1 Q13153 p21 (RAC1) activated kinase 1 Kinase 1.3E-03 0.494 0.808 2
PPP6C O00743 protein phosphatase 6 catalytic subunit 0.86 0.729 0.231 2
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885 2
TRRAP Q9Y4A5 transformation/transcription domain associated protein 1.00 0.572 0.692 2
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923 3
GNA11 P29992 G protein subunit alpha 11 Enzyme modulator 0.89 0.563 0.731 3
GNAQ P50148 G protein subunit alpha q Enzyme modulator 0.98 0.516 0.808 3
MAP2K2 P36507 mitogen-activated protein kinase kinase 2 Kinase 0.97 0.534 0.731 3
RAC1 P63000 Rac family small GTPase 1 Enzyme modulator 0.76 0.429 0.962 3
DDB2 Q92466 damage specific DNA binding protein 2 Nucleic acid binding 7.4E-06 0.576 0.654 4
ERCC3 P19447 ERCC excision repair 3, TFIIH core complex helicase subunit Enzyme 3.4E-11 0.504 0.846 4
ERCC5 P28715 ERCC excision repair 5, endonuclease 2.7E-13 0.499 0.731 4
XPA P23025 XPA, DNA damage recognition and repair factor Nucleic acid binding 7.9E-05 0.520 0.846 4
XPC Q01831 XPC complex subunit, DNA damage recognition and repair factor Nucleic acid binding 3.7E-11 0.504 0.808 4
CDK4 P11802 cyclin dependent kinase 4 Kinase 6.3E-02 0.412 0.808 5
PDGFRA P16234 platelet derived growth factor receptor alpha Kinase 1.00 0.415 0.808 5
ERBB4 Q15303 erb-b2 receptor tyrosine kinase 4 Kinase 1.00 0.455 0.846 6
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885 8
ERCC4 Q92889 ERCC excision repair 4, endonuclease catalytic subunit Enzyme 1.4E-12 0.468 0.846 8
NF1 P21359 neurofibromin 1 Enzyme modulator 0.90 0.440 0.885 8
CUX1 P39880 Q13948 cut like homeobox 1 Transcription factor 1.00 0.465 0.846 9
RET P07949 ret proto-oncogene Kinase 1.00 0.392 0.885 9
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846 10