Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
NGFR P08138 nerve growth factor receptor Receptor 9.8E-02 0.477 0.846 23
S100B P04271 S100 calcium binding protein B Calcium-binding protein 4.4E-02 0.383 0.923 23
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962 23
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885 22
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846 22
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846 21
HSPD1 P10809 heat shock protein family D (Hsp60) member 1 0.99 0.432 0.808 20
SERPINF1 P36955 serpin family F member 1 Enzyme modulator 7.8E-08 0.460 0.846 20
PTGS1 P23219 prostaglandin-endoperoxide synthase 1 Enzyme 6.2E-07 0.460 0.885 19
INS P01308 insulin 0.30 0.445 0.923 18
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 17
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923 16
NTRK2 Q16620 neurotrophic receptor tyrosine kinase 2 Kinase 1.00 0.479 0.808 14
ATP7A Q04656 ATPase copper transporting alpha Transporter 1.00 0.494 0.769 13
IRS1 P35568 insulin receptor substrate 1 2.4E-02 0.488 0.769 13
HSF1 Q00613 heat shock transcription factor 1 Transcription factor 0.75 0.507 0.769 12
LRP1 Q07954 LDL receptor related protein 1 1.00 0.482 0.769 12
MME P08473 membrane metalloendopeptidase Enzyme 1.5E-18 0.407 0.808 12
ATP5F1A P25705 ATP synthase F1 subunit alpha Transporter 1.00 0.604 0.731 11
IKBKB O14920 inhibitor of nuclear factor kappa B kinase subunit beta Kinase 0.99 0.506 0.846 11
BACE1 P56817 beta-secretase 1 Enzyme 0.88 0.559 0.769 10
CDK5 Q00535 cyclin dependent kinase 5 Kinase 0.14 0.495 0.846 10
GAPDH P04406 glyceraldehyde-3-phosphate dehydrogenase Enzyme 0.11 0.447 0.808 10
ADAM17 P78536 ADAM metallopeptidase domain 17 1.00 0.453 0.808 9