Source: LHGDN

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
PLAUR Q03405 plasminogen activator, urokinase receptor 5.3E-03 0.536 0.731 35
HLA-A P04439 major histocompatibility complex, class I, A 1.3E-03 0.370 0.846 34
CASP8 Q14790 caspase 8 Enzyme 3.7E-06 0.404 0.923 33
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885 32
CDKN2B P42772 cyclin dependent kinase inhibitor 2B 7.3E-03 0.417 0.769 31
S100B P04271 S100 calcium binding protein B Calcium-binding protein 4.4E-02 0.383 0.923 30
ENG P17813 endoglin 1.00 0.446 0.846 28
MGMT P16455 O-6-methylguanine-DNA methyltransferase 1.2E-07 0.412 0.885 28
RASSF1 Q9NS23 Ras association domain family member 1 Enzyme modulator 4.9E-06 0.420 0.808 28
TP73 O15350 tumor protein p73 Transcription factor 1.00 0.449 0.808 27
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885 26
TNC P24821 tenascin C 1.3E-07 0.433 0.846 26
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962 24
TYMS P04818 thymidylate synthetase Enzyme 0.72 0.425 0.846 24
CST3 P01034 cystatin C 3.9E-03 0.436 0.808 22
GJB2 P29033 gap junction protein beta 2 Cell-cell junction 6.6E-16 0.441 0.846 22
VHL P40337 von Hippel-Lindau tumor suppressor Enzyme 8.0E-02 0.443 0.846 22
PGR P06401 progesterone receptor Nuclear receptor 5.1E-02 0.426 0.885 21
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885 20
CA9 Q16790 carbonic anhydrase 9 1.3E-09 0.483 0.731 19
MTRR Q9UBK8 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 2.2E-14 0.502 0.808 19
TGM2 P21980 transglutaminase 2 Enzyme 6.8E-18 0.445 0.808 19
TOP2A P11388 DNA topoisomerase II alpha 0.99 0.497 0.731 19
MTR Q99707 5-methyltetrahydrofolate-homocysteine methyltransferase 2.4E-12 0.482 0.808 18