|
rs1800795
|
|
Tuberculosis
|
|
0.040 |
GeneticVariation
|
BEFREE |
Collectively, this meta-analysis proved that IL-6 rs1800795, IL-18 rs1946518 and IL-18 rs187238 polymorphisms may confer susceptibility to TB, especially for Asians.
|
31676365 |
2020 |
|
rs2069837
|
|
Chronic Periodontitis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Complete physical mapping of IL6 (using tag SNPs) was carried out for the first time, unveiling allele G of polymorphism rs2069837 (located in the second intron of IL6) as a suggestive marker of protection against chronic periodontitis in a Brazilian population.
|
27172922 |
2017 |
|
rs1800796
|
|
Primary malignant neoplasm
|
|
0.030 |
GeneticVariation
|
BEFREE |
Considering these promising results, IL-6 promoter including rs1800795, rs1800796 and rs1800797 may be a tumor marker for cancer therapy.
|
29552316 |
2018 |
|
rs1800796
|
|
Malignant Neoplasms
|
|
0.030 |
GeneticVariation
|
BEFREE |
Considering these promising results, IL-6 promoter including rs1800795, rs1800796 and rs1800797 may be a tumor marker for cancer therapy.
|
29552316 |
2018 |
|
rs1800797
|
|
Primary malignant neoplasm
|
|
0.020 |
GeneticVariation
|
BEFREE |
Considering these promising results, IL-6 promoter including rs1800795, rs1800796 and rs1800797</span> may be a tumor marker for cancer therapy.
|
29552316 |
2018 |
|
rs1800797
|
|
Malignant Neoplasms
|
|
0.020 |
GeneticVariation
|
BEFREE |
Considering these promising results, IL-6 promoter including rs1800795, rs1800796 and rs1800797</span> may be a tumor marker for cancer therapy.
|
29552316 |
2018 |
|
rs1800797
|
|
Neoplasms
|
|
0.010 |
GeneticVariation
|
BEFREE |
Considering these promising results, IL-6 promoter including rs1800795, rs1800796 and rs1800797 may be a tumor marker for cancer therapy.
|
29552316 |
2018 |
|
rs1800796
|
|
Malignant neoplasm of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
CRP rs2794520 (OR=1.64, 95% CI=1.19-2.26) and IL6 rs1800796 (OR=1.41, 95% CI=1.02-1.96) were associated with lung cancer risk.
|
24139238 |
2014 |
|
rs1800796
|
|
Primary malignant neoplasm of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
CRP rs2794520 (OR=1.64, 95% CI=1.19-2.26) and IL6 rs1800796 (OR=1.41, 95% CI=1.02-1.96) were associated with lung cancer risk.
|
24139238 |
2014 |
|
rs1800796
|
|
Carcinoma of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
CRP rs2794520 (OR=1.64, 95% CI=1.19-2.26) and IL6 rs1800796 (OR=1.41, 95% CI=1.02-1.96) were associated with lung cancer risk.
|
24139238 |
2014 |
|
rs1800795
|
|
Colorectal Carcinoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
Data from a multi-center case-control study of colon (N = 1579 cases and N = 1977 controls) and rectal (N = 794 cases and N = 1005 controls) cancer were used to evaluate the association between the rs1800795 and rs1800796 IL6 polymorphisms and CRC.
|
17694420 |
2007 |
|
rs1800796
|
|
Colorectal Carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
Data from a multi-center case-control study of colon (N = 1579 cases and N = 1977 controls) and rectal (N = 794 cases and N = 1005 controls) cancer were used to evaluate the association between the rs1800795 and rs1800796 IL6 polymorphisms and CRC.
|
17694420 |
2007 |
|
rs1800796
|
|
Congenital Dysplasia Of The Hip
|
|
0.020 |
GeneticVariation
|
BEFREE |
Data suggest association between TGFB1 29 T → C transition (rs1800470) and IL6 -572G → C transversion (rs1800796) with DDH, and also a possibility of TGF-beta1 and IL-6 interaction in DDH pathogenesis.
|
25603974 |
2015 |
|
rs1800795
|
|
Degenerative polyarthritis
|
|
0.030 |
GeneticVariation
|
BEFREE |
Data were analysed in conjuntion with published data on rs1800797 from the Genetics of OA and Lifestyle study (UK) on 791 controls, 1034 knee and 997 hip OA cases and rs1800795 data on 75 hip OA cases and 96 controls from Italy.
|
20175976 |
2010 |
|
rs1800795
|
|
Proliferative vitreoretinopathy
|
|
0.010 |
GeneticVariation
|
BEFREE |
Differences in genotype distributions between patients with RRD with or without PVR were detected in rs1800795 (IL6) (P = 0.04), rs1800871 (in the vicinity of the IL10) (P = 0.034), and rs1800471 (TGFB1) (P = 0.032).
|
30807515 |
2019 |
|
rs2069837
|
|
Cerebral Palsy
|
|
0.010 |
GeneticVariation
|
BEFREE |
Differences were found between spastic CP and controls in males for rs2069837; between CP with periventricular leukomalacia and controls in males for rs1800796 and rs2066992; and between term CP and controls in males for rs2069837.
|
24903966 |
2014 |
|
rs2069837
|
|
Leukomalacia, Periventricular
|
|
0.010 |
GeneticVariation
|
BEFREE |
Differences were found between spastic CP and controls in males for rs2069837; between CP with periventricular leukomalacia and controls in males for rs1800796 and rs2066992; and between term CP and controls in males for rs2069837.
|
24903966 |
2014 |
|
rs1800796
|
|
Cerebral Palsy
|
|
0.010 |
GeneticVariation
|
BEFREE |
Differences were found between spastic CP and controls in males for rs2069837; between CP with periventricular leukomalacia and controls in males for rs1800796 and rs2066992; and between term CP and controls in males for rs2069837.
|
24903966 |
2014 |
|
rs2066992
|
|
Cerebral Palsy
|
|
0.010 |
GeneticVariation
|
BEFREE |
Differences were found between spastic CP and controls in males for rs2069837; between CP with periventricular leukomalacia and controls in males for rs1800796 and rs2066992; and between term CP and controls in males for rs2069837.
|
24903966 |
2014 |
|
rs1800796
|
|
Leukomalacia, Periventricular
|
|
0.010 |
GeneticVariation
|
BEFREE |
Differences were found between spastic CP and controls in males for rs2069837; between CP with periventricular leukomalacia and controls in males for rs1800796 and rs2066992; and between term CP and controls in males for rs2069837.
|
24903966 |
2014 |
|
rs1800795
|
|
Malignant neoplasm of prostate
|
|
0.070 |
GeneticVariation
|
BEFREE |
Direct sequencing of the PCR amplicon from genomic DNA was used for genotyping rs1800795 in all subjects [age-matched controls (N = 140) and prostate cancer patients (N = 164)].
|
24446297 |
2014 |
|
rs1800795
|
|
Prostate carcinoma
|
|
0.070 |
GeneticVariation
|
BEFREE |
Direct sequencing of the PCR amplicon from genomic DNA was used for genotyping rs1800795 in all subjects [age-matched controls (N = 140) and prostate cancer patients (N = 164)].
|
24446297 |
2014 |
|
rs1800795
|
|
Depressive Symptoms
|
|
0.030 |
GeneticVariation
|
BEFREE |
Epidemiologic analyses verified the health significance of those molecular interactions by documenting increased 10-year mortality risk associated with late-life depressive symptoms that occurred solely for homozygous carriers of the GATA1-sensitive G allele of rs1800795.
|
20176930 |
2010 |
|
rs1800795
|
|
Malignant neoplasm of stomach
|
|
0.020 |
GeneticVariation
|
BEFREE |
Epidemiological studies have evaluated the associations between interleukin-6 (IL-6) gene -174 C/G (rs1800795) and -572 C/G (rs1800796) polymorphisms and gastric cancer (GC) risk, but results and conclusions remain controversial.
|
22711691 |
2012 |
|
rs1800795
|
|
Stomach Carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
Epidemiological studies have evaluated the associations between interleukin-6 (IL-6) gene -174 C/G (rs1800795) and -572 C/G (rs1800796) polymorphisms and gastric cancer (GC) risk, but results and conclusions remain controversial.
|
22711691 |
2012 |