Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3630
Gene Symbol: INS
INS
P01308 insulin 309 0.458 0.828 0.32 0.700 1.000 16 0 1995 2016
Entrez Id: 2645
Gene Symbol: GCK
GCK
P35557 glucokinase 160 0.547 0.586 0.66 0.500 0.988 81 6 1992 2017
Entrez Id: 3643
Gene Symbol: INSR
INSR
P06213 insulin receptor 338 0.459 0.724 2.0E-05 0.500 0.929 15 0 1984 2016
Entrez Id: 5579
Gene Symbol: PRKCB
PRKCB
P05771 protein kinase C beta calcium-binding protein; kinase; transfer/carrier protein; transferase 88 0.564 0.690 1.00 0.500 2 0 2005 2007
Entrez Id: 2641
Gene Symbol: GCG
GCG
P01275 glucagon 152 0.529 0.655 2.5E-02 0.400 0.967 32 0 1981 2018
Entrez Id: 3651
Gene Symbol: PDX1
PDX1
P52945 pancreatic and duodenal homeobox 1 135 0.557 0.483 2.0E-02 0.380 1.000 10 0 1999 2013
Entrez Id: 177
Gene Symbol: AGER
AGER
Q15109 advanced glycosylation end-product specific receptor cell adhesion molecule; receptor 232 0.472 0.724 3.4E-16 0.380 1.000 9 0 2009 2018
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
P29474 nitric oxide synthase 3 467 0.401 0.862 8.9E-07 0.370 1.000 7 1 2001 2015
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
Q16236 nuclear factor, erythroid 2 like 2 cytoskeletal protein; hydrolase; nucleic acid binding; transcription factor 376 0.420 0.862 3.5E-03 0.340 1.000 5 0 2008 2017
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 oxidoreductase 832 0.338 0.897 1.00 0.340 1.000 4 0 2003 2013
Entrez Id: 8660
Gene Symbol: IRS2
IRS2
Q9Y4H2 insulin receptor substrate 2 96 0.559 0.552 0.99 0.320 0.500 4 0 2005 2016
Entrez Id: 6667
Gene Symbol: SP1
SP1
P08047 Sp1 transcription factor nucleic acid binding; transcription factor 159 0.508 0.724 1.00 0.320 1.000 2 0 2001 2017
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
P48357 leptin receptor defense/immunity protein; signaling molecule 264 0.474 0.793 1.00 0.310 1.000 6 0 1986 2015
Entrez Id: 2876
Gene Symbol: GPX1
GPX1
P07203 glutathione peroxidase 1 oxidoreductase 172 0.498 0.759 4.5E-05 0.310 1.000 2 0 2004 2010
Entrez Id: 1281
Gene Symbol: COL3A1
COL3A1
P02461 collagen type III alpha 1 chain 222 0.510 0.759 1.00 0.310 1.000 1 0 2010 2010
Entrez Id: 2200
Gene Symbol: FBN1
FBN1
P35555 fibrillin 1 calcium-binding protein; cell adhesion molecule; extracellular matrix protein; signaling molecule 413 0.469 0.690 1.00 0.310 1.000 1 0 2010 2010
Entrez Id: 231
Gene Symbol: AKR1B1
AKR1B1
P15121 aldo-keto reductase family 1 member B oxidoreductase 132 0.536 0.621 1.5E-04 0.300 1.000 13 0 1998 2017
Entrez Id: 1728
Gene Symbol: NQO1
NQO1
P15559 NAD(P)H quinone dehydrogenase 1 230 0.467 0.724 1.0E-09 0.300 1 0 2013 2013
Entrez Id: 3290
Gene Symbol: HSD11B1
HSD11B1
P28845 hydroxysteroid 11-beta dehydrogenase 1 82 0.577 0.655 0.41 0.300 1 0 2004 2004
Entrez Id: 6492
Gene Symbol: SIM1
SIM1
P81133 SIM bHLH transcription factor 1 nucleic acid binding; transcription factor 61 0.701 0.345 1.00 0.300 1 0 2008 2008
Entrez Id: 3159
Gene Symbol: HMGA1
HMGA1
P17096 high mobility group AT-hook 1 nucleic acid binding 124 0.532 0.552 0.83 0.300 1 0 2014 2014
Entrez Id: 10549
Gene Symbol: PRDX4
PRDX4
Q13162 peroxiredoxin 4 oxidoreductase 25 0.707 0.448 0.13 0.300 1 0 2011 2011
Entrez Id: 2740
Gene Symbol: GLP1R
GLP1R
P43220 glucagon like peptide 1 receptor 73 0.598 0.586 0.28 0.250 0.600 6 0 1999 2016
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1035 0.312 0.931 0.13 0.230 1.000 4 0 2006 2015
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A
Q9UBK2 PPARG coactivator 1 alpha transcription factor 191 0.497 0.828 1.00 0.220 1.000 4 0 2006 2016