Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6647
Gene Symbol: SOD1
SOD1 		0.300 Biomarker disease CTD_human Identification of new mutations in the Cu/Zn superoxide dismutase gene of patients with familial amyotrophic lateral sclerosis. 7887412 1995
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		0.300 Biomarker disease CTD_human Enhanced superoxide dismutase-2 immunoreactivity of astrocytes and occasional neurons in amyotrophic lateral sclerosis. 8866423 1996
Entrez Id: 6647
Gene Symbol: SOD1
SOD1 		0.300 Biomarker disease CTD_human Clinical and functional investigation of 10 missense mutations and a novel frameshift insertion mutation of the gene for copper-zinc superoxide dismutase in UK families with amyotrophic lateral sclerosis. 9065559 1997
Entrez Id: 6647
Gene Symbol: SOD1
SOD1 		0.300 Biomarker disease CTD_human Renal tubular impairment during riluzole therapy. 10025816 1999
Entrez Id: 6647
Gene Symbol: SOD1
SOD1 		0.300 Biomarker disease CTD_human Increased reactive oxygen species in familial amyotrophic lateral sclerosis with mutations in SOD1. 10930589 2000
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		0.300 Biomarker disease CTD_human Increased expression of the pro-inflammatory enzyme cyclooxygenase-2 in amyotrophic lateral sclerosis. 11220737 2001
Entrez Id: 6647
Gene Symbol: SOD1
SOD1 		0.300 Biomarker disease CTD_human Increased expression of the pro-inflammatory enzyme cyclooxygenase-2 in amyotrophic lateral sclerosis. 11220737 2001
Entrez Id: 6647
Gene Symbol: SOD1
SOD1 		0.300 Biomarker disease CTD_human Oxidative stress causes abnormal accumulation of familial amyotrophic lateral sclerosis-related mutant SOD1 in transgenic Caenorhabditis elegans. 11590119 2001
Entrez Id: 6506
Gene Symbol: SLC1A2
SLC1A2 		0.300 Biomarker disease CTD_human Transgenic SOD1 G93A mice develop reduced GLT-1 in spinal cord without alterations in cerebrospinal fluid glutamate levels. 11723166 2001
Entrez Id: 2670
Gene Symbol: GFAP
GFAP 		0.300 Biomarker disease CTD_human Transgenic SOD1 G93A mice develop reduced GLT-1 in spinal cord without alterations in cerebrospinal fluid glutamate levels. 11723166 2001
Entrez Id: 6647
Gene Symbol: SOD1
SOD1 		0.300 Biomarker disease CTD_human Transgenic SOD1 G93A mice develop reduced GLT-1 in spinal cord without alterations in cerebrospinal fluid glutamate levels. 11723166 2001
Entrez Id: 6647
Gene Symbol: SOD1
SOD1 		0.300 Biomarker disease CTD_human A therapeutic role for cyclooxygenase-2 inhibitors in a transgenic mouse model of amyotrophic lateral sclerosis. 12586733 2003
Entrez Id: 6647
Gene Symbol: SOD1
SOD1 		0.300 Biomarker disease CTD_human Glycation proceeds faster in mutated Cu, Zn-superoxide dismutases related to familial amyotrophic lateral sclerosis. 12626432 2003
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		0.300 Biomarker disease CTD_human Integrative role of cPLA with COX-2 and the effect of non-steriodal anti-inflammatory drugs in a transgenic mouse model of amyotrophic lateral sclerosis. 15816863 2005
Entrez Id: 5321
Gene Symbol: PLA2G4A
PLA2G4A 		0.300 Biomarker disease CTD_human Integrative role of cPLA with COX-2 and the effect of non-steriodal anti-inflammatory drugs in a transgenic mouse model of amyotrophic lateral sclerosis. 15816863 2005
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1 		0.300 Biomarker disease CTD_human Activity and expression of glutathione S-transferase pi in patients with amyotrophic lateral sclerosis. 16109392 2006
Entrez Id: 6647
Gene Symbol: SOD1
SOD1 		0.300 Biomarker disease CTD_human Familial amyotrophic lateral sclerosis with frontotemporal dementia is linked to a locus on chromosome 9p13.2-21.3. 16495328 2006
Entrez Id: 2936
Gene Symbol: GSR
GSR 		0.300 Biomarker disease CTD_human Alterations in anti-oxidative defence enzymes in erythrocytes from sporadic amyotrophic lateral sclerosis (SALS) and familial ALS patients. 16681429 2006
Entrez Id: 25978
Gene Symbol: CHMP2B
CHMP2B 		0.300 Biomarker disease CTD_human ALS phenotypes with mutations in CHMP2B (charged multivesicular body protein 2B). 16807408 2006
Entrez Id: 6647
Gene Symbol: SOD1
SOD1 		0.300 Biomarker disease CTD_human Metallothionein proteins expression, copper and zinc concentrations, and lipid peroxidation level in a rodent model for amyotrophic lateral sclerosis. 17097207 2007
Entrez Id: 6647
Gene Symbol: SOD1
SOD1 		0.300 Biomarker disease CTD_human Protein-bound crotonaldehyde accumulates in the spinal cord of superoxide dismutase-1 mutation-associated familial amyotrophic lateral sclerosis and its transgenic mouse model. 17319283 2007
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.300 Biomarker disease CTD_human Transcription factor p53 in degenerating spinal cords. 17434459 2007
Entrez Id: 6647
Gene Symbol: SOD1
SOD1 		0.300 Biomarker disease CTD_human Identification and characterization of cholest-4-en-3-one, oxime (TRO19622), a novel drug candidate for amyotrophic lateral sclerosis. 17496168 2007
Entrez Id: 1804
Gene Symbol: DPP6
DPP6 		0.300 Biomarker disease CTD_human Genetic variation in DPP6 is associated with susceptibility to amyotrophic lateral sclerosis. 18084291 2008
Entrez Id: 6647
Gene Symbol: SOD1
SOD1 		0.300 Biomarker disease CTD_human Superoxide dismutase 1 mutants related to amyotrophic lateral sclerosis induce endoplasmic stress in neuro2a cells. 18233996 2008