×
Entrez Id:
400916
Gene Symbol:
CHCHD10
CHCHD10
0.010
Biomarker
disease
BEFREE
Screening of CHCHD10 in a French cohort confirms the involvement of this gene in frontotemporal dementia with amyotrophic lateral sclerosis patients.
25155093
2014
×
Entrez Id:
6647
Gene Symbol:
SOD1
SOD1
0.300
Biomarker
disease
CTD_human
Resveratrol treatment reduces the vulnerability of SH-SY5Y cells and cortical neurons overexpressing SOD1-G93A to Thimerosal toxicity through SIRT1/DREAM/PDYN pathway.
30503815
2019
×
Entrez Id:
2521
Gene Symbol:
FUS
FUS
0.300
Biomarker
disease
CTD_human
ALS mutations of FUS suppress protein translation and disrupt the regulation of nonsense-mediated decay.
30455313
2018
×
Entrez Id:
5444
Gene Symbol:
PON1
PON1
0.300
Biomarker
disease
CTD_human
Organophosphate neurotoxicity to the voluntary motor system on the trail of environment-caused amyotrophic lateral sclerosis: the known, the misknown, and the unknown.
28070599
2017
×
Entrez Id:
6311
Gene Symbol:
ATXN2
ATXN2
0.300
Biomarker
disease
CTD_human
Identification of risk factors associated with onset and progression of amyotrophic lateral sclerosis using systematic review and meta-analysis.
27377857
2017
×
Entrez Id:
755
Gene Symbol:
CFAP410
CFAP410
0.300
Biomarker
disease
CTD_human
Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis.
27455348
2016
×
Entrez Id:
23256
Gene Symbol:
SCFD1
SCFD1
0.300
Biomarker
disease
CTD_human
Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis.
27455348
2016
×
Entrez Id:
4750
Gene Symbol:
NEK1
NEK1
0.300
Biomarker
disease
CTD_human
NEK1 mutations in familial amyotrophic lateral sclerosis.
26945885
2016
×
Entrez Id:
4750
Gene Symbol:
NEK1
NEK1
0.300
Biomarker
disease
CTD_human
NEK1 variants confer susceptibility to amyotrophic lateral sclerosis.
27455347
2016
×
Entrez Id:
4336
Gene Symbol:
MOBP
MOBP
0.300
Biomarker
disease
CTD_human
Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis.
27455348
2016
×
Entrez Id:
10280
Gene Symbol:
SIGMAR1
SIGMAR1
0.300
Biomarker
disease
CTD_human
Lack of synergistic effect of resveratrol and sigma-1 receptor agonist (PRE-084) in SOD1G⁹³A ALS mice: overlapping effects or limited therapeutic opportunity?
24885036
2014
×
Entrez Id:
6647
Gene Symbol:
SOD1
SOD1
0.300
Biomarker
disease
CTD_human
Lack of synergistic effect of resveratrol and sigma-1 receptor agonist (PRE-084) in SOD1G⁹³A ALS mice: overlapping effects or limited therapeutic opportunity?
24885036
2014
×
Entrez Id:
23435
Gene Symbol:
TARDBP
TARDBP
0.300
Biomarker
disease
CTD_human
A high-content screen identifies novel compounds that inhibit stress-induced TDP-43 cellular aggregation and associated cytotoxicity.
24019256
2014
×
Entrez Id:
10133
Gene Symbol:
OPTN
OPTN
0.300
Biomarker
disease
CTD_human
Optineurin associates with the podocyte Golgi complex to maintain its structure.
25096716
2014
×
Entrez Id:
6647
Gene Symbol:
SOD1
SOD1
0.300
Biomarker
disease
CTD_human
Identification of a misfolded region in superoxide dismutase 1 that is exposed in amyotrophic lateral sclerosis.
25164820
2014
×
Entrez Id:
6647
Gene Symbol:
SOD1
SOD1
0.300
Biomarker
disease
CTD_human
Motor neuron dysfunction in a mouse model of ALS: gender-dependent effect of P2X7 antagonism.
23583883
2013
TNFRSF21
0.300
Biomarker
disease
CTD_human
Death receptor 6 (DR6) antagonist antibody is neuroprotective in the mouse SOD1G93A model of amyotrophic lateral sclerosis.
24113175
2013
×
Entrez Id:
57172
Gene Symbol:
CAMK1G
CAMK1G
0.300
Biomarker
disease
CTD_human
Genome-wide association analyses in Han Chinese identify two new susceptibility loci for amyotrophic lateral sclerosis.
23624525
2013
×
Entrez Id:
23435
Gene Symbol:
TARDBP
TARDBP
0.300
Biomarker
disease
CTD_human
Reducing TDP-43 aggregation does not prevent its cytotoxicity.
24252504
2013
×
Entrez Id:
23435
Gene Symbol:
TARDBP
TARDBP
0.300
Biomarker
disease
CTD_human
Inhibition of RNA lariat debranching enzyme suppresses TDP-43 toxicity in ALS disease models.
23104007
2012
×
Entrez Id:
51163
Gene Symbol:
DBR1
DBR1
0.300
Therapeutic
disease
CTD_human
Inhibition of RNA lariat debranching enzyme suppresses TDP-43 toxicity in ALS disease models.
23104007
2012
×
Entrez Id:
23435
Gene Symbol:
TARDBP
TARDBP
0.300
Biomarker
disease
CTD_human
Inhibition of TDP-43 accumulation by bis(thiosemicarbazonato)-copper complexes.
22879928
2012
×
Entrez Id:
23435
Gene Symbol:
TARDBP
TARDBP
0.300
Biomarker
disease
CTD_human
Inorganic mercury within motor neurons does not cause the TDP-43 changes seen in sporadic ALS.
21167262
2011
×
Entrez Id:
6647
Gene Symbol:
SOD1
SOD1
0.300
Biomarker
disease
CTD_human
Bromocriptine methylate suppresses glial inflammation and moderates disease progression in a mouse model of amyotrophic lateral sclerosis.
21867702
2011
×
Entrez Id:
10133
Gene Symbol:
OPTN
OPTN
0.300
Biomarker
disease
CTD_human
Processing of optineurin in neuronal cells.
21059646
2011