Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 8878
Gene Symbol: SQSTM1
SQSTM1 		0.310 GeneticVariation disease BEFREE SQSTM1 mutations in French patients with frontotemporal dementia or frontotemporal dementia with amyotrophic lateral sclerosis. 24042580 2013
Entrez Id: 6647
Gene Symbol: SOD1
SOD1 		0.300 Biomarker disease CTD_human A common property of amyotrophic lateral sclerosis-associated variants: destabilization of the copper/zinc superoxide dismutase electrostatic loop. 19635794 2009
Entrez Id: 23435
Gene Symbol: TARDBP
TARDBP 		0.300 Biomarker disease CTD_human A high-content screen identifies novel compounds that inhibit stress-induced TDP-43 cellular aggregation and associated cytotoxicity. 24019256 2014
Entrez Id: 6647
Gene Symbol: SOD1
SOD1 		0.300 Biomarker disease CTD_human A therapeutic role for cyclooxygenase-2 inhibitors in a transgenic mouse model of amyotrophic lateral sclerosis. 12586733 2003
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1 		0.300 Biomarker disease CTD_human Activity and expression of glutathione S-transferase pi in patients with amyotrophic lateral sclerosis. 16109392 2006
Entrez Id: 2521
Gene Symbol: FUS
FUS 		0.300 Biomarker disease CTD_human ALS mutations of FUS suppress protein translation and disrupt the regulation of nonsense-mediated decay. 30455313 2018
Entrez Id: 25978
Gene Symbol: CHMP2B
CHMP2B 		0.300 Biomarker disease CTD_human ALS phenotypes with mutations in CHMP2B (charged multivesicular body protein 2B). 16807408 2006
Entrez Id: 2936
Gene Symbol: GSR
GSR 		0.300 Biomarker disease CTD_human Alterations in anti-oxidative defence enzymes in erythrocytes from sporadic amyotrophic lateral sclerosis (SALS) and familial ALS patients. 16681429 2006
Entrez Id: 6647
Gene Symbol: SOD1
SOD1 		0.300 Biomarker disease CTD_human Bromocriptine methylate suppresses glial inflammation and moderates disease progression in a mouse model of amyotrophic lateral sclerosis. 21867702 2011
Entrez Id: 6647
Gene Symbol: SOD1
SOD1 		0.300 Biomarker disease CTD_human Clinical and functional investigation of 10 missense mutations and a novel frameshift insertion mutation of the gene for copper-zinc superoxide dismutase in UK families with amyotrophic lateral sclerosis. 9065559 1997
Entrez Id: 27242
Gene Symbol: TNFRSF21
TNFRSF21 		0.300 Biomarker disease CTD_human Death receptor 6 (DR6) antagonist antibody is neuroprotective in the mouse SOD1G93A model of amyotrophic lateral sclerosis. 24113175 2013
Entrez Id: 6647
Gene Symbol: SOD1
SOD1 		0.300 Biomarker disease CTD_human Disrupted zinc-binding sites in structures of pathogenic SOD1 variants D124V and H80R. 20515040 2010
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		0.300 Biomarker disease CTD_human Enhanced superoxide dismutase-2 immunoreactivity of astrocytes and occasional neurons in amyotrophic lateral sclerosis. 8866423 1996
Entrez Id: 6647
Gene Symbol: SOD1
SOD1 		0.300 Biomarker disease CTD_human Familial amyotrophic lateral sclerosis with frontotemporal dementia is linked to a locus on chromosome 9p13.2-21.3. 16495328 2006
Entrez Id: 959
Gene Symbol: CD40LG
CD40LG 		0.300 Therapeutic disease CTD_human From transcriptome analysis to therapeutic anti-CD40L treatment in the SOD1 model of amyotrophic lateral sclerosis. 20348957 2010
Entrez Id: 6647
Gene Symbol: SOD1
SOD1 		0.300 Biomarker disease CTD_human From transcriptome analysis to therapeutic anti-CD40L treatment in the SOD1 model of amyotrophic lateral sclerosis. 20348957 2010
Entrez Id: 203228
Gene Symbol: C9orf72
C9orf72 		0.310 Biomarker disease CTD_human Genetic variation associated with the occurrence and progression of neurological disorders. 27713094 2017
Entrez Id: 1804
Gene Symbol: DPP6
DPP6 		0.300 Biomarker disease CTD_human Genetic variation in DPP6 is associated with susceptibility to amyotrophic lateral sclerosis. 18084291 2008
Entrez Id: 755
Gene Symbol: CFAP410
CFAP410 		0.300 Biomarker disease CTD_human Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis. 27455348 2016
Entrez Id: 23256
Gene Symbol: SCFD1
SCFD1 		0.300 Biomarker disease CTD_human Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis. 27455348 2016
Entrez Id: 4336
Gene Symbol: MOBP
MOBP 		0.300 Biomarker disease CTD_human Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis. 27455348 2016
Entrez Id: 57172
Gene Symbol: CAMK1G
CAMK1G 		0.300 Biomarker disease CTD_human Genome-wide association analyses in Han Chinese identify two new susceptibility loci for amyotrophic lateral sclerosis. 23624525 2013
Entrez Id: 23025
Gene Symbol: UNC13A
UNC13A 		0.300 Biomarker disease CTD_human Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis. 19734901 2009
Entrez Id: 6647
Gene Symbol: SOD1
SOD1 		0.300 Biomarker disease CTD_human Glycation proceeds faster in mutated Cu, Zn-superoxide dismutases related to familial amyotrophic lateral sclerosis. 12626432 2003
Entrez Id: 6647
Gene Symbol: SOD1
SOD1 		0.300 Biomarker disease CTD_human Identification and characterization of cholest-4-en-3-one, oxime (TRO19622), a novel drug candidate for amyotrophic lateral sclerosis. 17496168 2007