|
rs5182
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In a preliminary study we found no association between the distribution of the C/T573 polymorphic site and cardiovascular disease, such as essential hypertension (n = 20) coronary artery disease (n = 16) hypertrophic cardiomyopathy (n = 12) or dilated cardiomyopathy (n = 21).
|
7713099 |
1994 |
|
rs1801177
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Two common coding sequence mutations of lipoprotein lipase (serine447-ter, producing a carboxy terminal truncation; and asp9-asn variants) were studied in 329 Caucasian subjects, of whom 243 had angiographic features of premature atheroscelerosis (220 with coronary artery disease; 23 with coronary and peripheral artery disease).
|
8835323 |
1995 |
|
rs751377893
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Evidence against heterozygous coagulation factor V 1691 G-->A mutation with resistance to activated protein C being a risk factor for coronary artery disease and myocardial infarction.
|
8581514 |
1995 |
|
rs1801177
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The Asp9 Asn mutation in the lipoprotein lipase gene is associated with increased progression of coronary atherosclerosis. REGRESS Study Group, Interuniversity Cardiology Institute, Utrecht, The Netherlands. Regression Growth Evaluation Statin Study.
|
8873668 |
1996 |
|
rs1264352930
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Delayed postprandial retinyl palmitate and squalene removal in a patient heterozygous for apolipoprotein A-IFIN mutation (Leu 159-->Arg) and low HDL cholesterol level without coronary artery disease.
|
9125314 |
1996 |
|
rs1384889210
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Compound heterozygosity for a structural apolipoprotein A-I variant, apo A-I(L141R)Pisa, and an apolipoprotein A-I null allele in patients with absence of HDL cholesterol, corneal opacifications, and coronary heart disease.
|
8840853 |
1996 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A common mutation (nucleotide 677 C-->T) has been described recently in the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene, which results in a valine for alanine substitution, a thermolabile enzyme, and a tendency to elevate plasma homocysteine levels and which has been proposed to contribute importantly to coronary artery disease.
|
8994411 |
1997 |
|
rs267606661
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Apolipoprotein E R112; R251G: a carboxy-terminal variant found in patients with hyperlipidemia and coronary heart disease.
|
9360638 |
1997 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In this generally well-nourished population, men with the +/+ genotype for the C677T mutation in the methylenetetrahydrofolate reductase gene have no increase in risk of coronary heart disease, even when intake of folate or other B vitamins is low.
|
9708460 |
1998 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Mutation C677T of methylenetetrahydrofolate reductase gene is not associated with coronary artery disease, but possibly with albuminuria, in type 2 diabetic patients.
|
9806473 |
1998 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Recently, a common polymorphism in exon 7 of the eNOS gene (894G-->T) has been reported to be a strong risk factor for coronary artery disease.
|
9731617 |
1998 |
|
rs662
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Studies have been conducted to evaluate the possible "protective" role of PON, and especially the influence of the Arg-->Gln 192 polymorphism, in coronary artery disease.
|
9746266 |
1998 |
|
rs141383962
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Studies have been conducted to evaluate the possible "protective" role of PON, and especially the influence of the Arg-->Gln 192 polymorphism, in coronary artery disease.
|
9746266 |
1998 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The present study extends previous observations by the finding that carriers of the N5,N10-methylenetetrahydrofolate reductase C677T TT genotype with various coronary high risk profiles had clearly higher coronary heart disease scores than individuals with at least one C677T C allele.
|
10337543 |
1999 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The homozygous C677T genotype has previously been associated with coronary heart disease in Ireland.
|
9974399 |
1999 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A common variant of the endothelial nitric oxide synthase (Glu298-->Asp) is a major risk factor for coronary artery disease in the UK.
|
10510054 |
1999 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The Glu-298-->Asp (894G-->T) mutation at exon 7 of the endothelial nitric oxide synthase gene and coronary artery disease.
|
10475066 |
1999 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A missense mutation of the nitric oxide synthase (eNOS) gene (Glu298Asp) in five patients with coronary artery disease--case reports.
|
10451235 |
1999 |
|
rs699
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The significant relations observed between the AGT M235T variant, its protein product, and the cardiovascular disease phenotypes provide evidence for a possible role of elevated circulating AGT in the pathogenesis of coronary artery disease.
|
10097233 |
1999 |
|
rs699
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Angiotensinogen T174M and M235T gene polymorphisms are associated with the extent of coronary atherosclerosis.
|
10488958 |
1999 |
|
rs4762
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Angiotensinogen T174M and M235T gene polymorphisms are associated with the extent of coronary atherosclerosis.
|
10488958 |
1999 |
|
rs142677199
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our observations allow the assumption that the p22 phox A640G gene polymorphism is independently associated with the presence and extent of coronary artery disease.
|
10488959 |
1999 |
|
rs150629733
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The p22 phox A640G gene polymorphism but not the C242T gene variation is associated with coronary heart disease in younger individuals.
|
10488959 |
1999 |
|
rs553350297
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our observations allow the assumption that the p22 phox A640G gene polymorphism is independently associated with the presence and extent of coronary artery disease.
|
10488959 |
1999 |
|
rs761401927
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our observations allow the assumption that the p22 phox A640G gene polymorphism is independently associated with the presence and extent of coronary artery disease.
|
10488959 |
1999 |