|
rs1010
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We considered five variants that were associated with coronary heart disease in two studies and confirmed in the Atherosclerosis Risk in Communities study: rs20455 (KIF6), rs3900940 (MYH15), rs7439293 (PALLD), rs2298566 (SNX19), and rs1010 (VAMP8).
|
18073581 |
2007 |
|
rs10118757
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association between rs10118757(A/G) in methylthioadenosine phosphorylase gene and coronary artery disease in Chinese Hans.
|
23462334 |
2013 |
|
rs10159239
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The Single Nucleotide Polymorphism rs10159239 was examined by logistic regression with known risk factors for Coronary artery disease and remained significant (0.035).
|
31639433 |
2020 |
|
rs1035071612
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The C766T low-density lipoprotein receptor related protein polymorphism and coronary artery disease, plasma lipoproteins, and longevity in the Czech population.
|
11357934 |
2001 |
|
rs1041981
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the present study, we investigated whether the LTA Thr26Asn polymorphism was associated with the extent of coronary atherosclerosis in a large cohort (n=1082) of well-documented coronary artery disease patients.
|
15973460 |
2005 |
|
rs1042522
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The Arg72 variant of the p53 functional polymorphism (rs1042522) is associated with coronary artery disease in young South Africans of Indian ancestry.
|
27436625 |
2016 |
|
rs1042579
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Thrombomodulin -33G/A and Ala455Val polymorphisms are associated with the risk of coronary artery disease: a meta-analysis including 12 584 patients.
|
25144670 |
2015 |
|
rs1042579
|
|
|
0.040 |
GeneticVariation |
BEFREE |
A combination of two common thrombomodulin gene variants (-1208-1209TTdelTT and A455V) influence risk of coronary heart disease: a prospective study in men.
|
15488871 |
2004 |
|
rs1042579
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Thrombomodulin Ala455Val polymorphism and risk of coronary heart disease.
|
11245641 |
2001 |
|
rs1042579
|
|
|
0.040 |
GeneticVariation |
BEFREE |
In smokers, the thrombomodulin Ala455Val variant allele emerges as a significant risk factor for coronary heart disease.
|
14523329 |
2003 |
|
rs1042713
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Cigarette smoking, carrier state of A or G allele of 46A>G and 79C>G polymorphisms of beta2-adrenergic receptor gene, and the risk of coronary artery disease.
|
18473266 |
2008 |
|
rs1042714
|
|
|
0.020 |
GeneticVariation |
BEFREE |
To examine the role of the Gln27Glu polymorphism of β2-AR in HF development and to assess the hypothesis that Gln27Glu is associated with coronary artery disease in patients with ischaemic HF.
|
28933308 |
2018 |
|
rs1042714
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Cigarette smoking, carrier state of A or G allele of 46A>G and 79C>G polymorphisms of beta2-adrenergic receptor gene, and the risk of coronary artery disease.
|
18473266 |
2008 |
|
rs1044925
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association between single nucleotide polymorphism rs1044925 and the risk of coronary artery disease and ischemic stroke.
|
24577316 |
2014 |
|
rs10455872
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Using the ICD-9-CM and ICD-10-CM maps, we conducted a PheWAS with a Lipoprotein(a) genetic variant, rs10455872, which replicated two known genotype-phenotype associations with similar effect sizes: coronary atherosclerosis (ICD-9-CM: P<.001; odds ratio (OR) 1.60 [95% CI 1.43-1.80] vs ICD-10-CM: P<.001; OR 1.60 [95% CI 1.43-1.80]) and chronic ischemic heart disease (ICD-9-CM: P<.001; OR 1.56 [95% CI 1.35-1.79] vs ICD-10-CM: P<.001; OR 1.47 [95% CI 1.22-1.77]).
|
31553307 |
2019 |
|
rs1045642
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The association of MDR1 C3435T and G2677T/A polymorphisms with plasma platelet-activating factor levels and coronary artery disease risk in Turkish population.
|
23816407 |
2013 |
|
rs1045642
|
|
|
0.020 |
GeneticVariation |
BEFREE |
ABCB1 C3435T polymorphism and the risk of coronary heart disease: a meta-analysis.
|
24328528 |
2014 |
|
rs1048990
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Quantitative assessment of the influence of PSMA6 variant (rs1048990) on coronary artery disease risk.
|
23111455 |
2013 |
|
rs1049255
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association analysis of rs1049255 and rs4673 transitions in p22phox gene with coronary artery disease: A case-control study and a computational analysis.
|
28474233 |
2017 |
|
rs1049353
|
|
|
0.010 |
GeneticVariation |
BEFREE |
G1359A polymorphism in the cannabinoid receptor-1 gene is associated with the presence of coronary artery disease in patients with type 2 diabetes.
|
22138970 |
2012 |
|
rs1049673
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Unconditional logistic regression analysis showed that gender, diabetes, high TG, LDL-C level and C carriers of rs1049673 significantly affected risk for premature coronary heart disease.
|
25299084 |
2014 |
|
rs1050450
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The objective was to determine whether the GPx1 Pro200Leu genetic variants modify the response of whole-blood glutathione peroxidase (GPx) activity to selenium supplementation in patients with coronary artery disease in New Zealand.
|
22952184 |
2012 |
|
rs10509681
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The G-50T polymorphism in CYP2J2 may be an important risk factor for the development of coronary heart disease events in African-Americans, whereas cigarette smoking may modify the relationship between the I264M and K399R polymorphisms in CYP2C8 and coronary heart disease risk in Caucasians.
|
17429317 |
2007 |
|
rs1051338
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Our findings show that the coronary artery disease-associated coding variant rs1051338 causes reduced lysosomal LAL protein and activity because of increased LAL degradation, providing a plausible causal mechanism of increased coronary artery disease risk.
|
28279971 |
2017 |
|
rs1051338
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Further, we characterized a second common exonic coding variant (rs1051339), which is predicted to alter LIPA signal peptide cleavage similarly to rs1051338</span>, yet is not linked to intronic variants. rs1051339 also does not impact LIPA function in vitro and confers no coronary artery disease risk.
|
31645127 |
2019 |