Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs7041
rs7041
GC
0.020 GeneticVariation BEFREE <b>Objectives</b>: The vitamin D binding protein encoded by the <i>GC</i> gene contains two single nucleotide polymorphisms (rs4588 and rs7041) that have been associated with disease outcome, these include periodontitis coronary heart disease and hypertension. 31559882

2019

dbSNP: rs8259
rs8259
BSG
0.010 GeneticVariation BEFREE <i>BSG</i> rs8259 TT genotype was associated with a decreased risk of CHF (OR = 0.83, 95% CI = 0.72-0.96, <i>p</i> = 0.010), especially in patients with hypertension (OR = 0.80, 95% CI = 0.68-0.95, <i>p</i> = 0.011) and coronary heart disease (OR = 0.81, 95% CI = 0.69-0.96, <i>p</i> = 0.013) after adjustment for multiple cardiovascular risk factors. 28230811

2017

dbSNP: rs6882076
rs6882076
0.010 GeneticVariation BEFREE <i>TIMD4</i> rs6882076 SNP Is Associated with Decreased Levels of Triglycerides and the Risk of Coronary Heart Disease and Ischemic Stroke. 31337960

2019

dbSNP: rs4646903
rs4646903
0.010 GeneticVariation BEFREE 1.The CYP1A1 T6235C polymorphism (rs4646903) gene polymorphism has been linked to the development of coronary heart disease and cigarette smoking-related lung cancer. 19650794

2010

dbSNP: rs1800588
rs1800588
0.020 GeneticVariation BEFREE 557 men aged 45-74 with stable coronary artery disease and 560 paired controls were genotyped for rs1800588. 23874450

2013

dbSNP: rs662
rs662
0.100 GeneticVariation BEFREE Coronary artery disease risk in Chinese type 2 diabetics: is there a role for paraxonase 1 gene (Q192R) polymorphism? 11375798

2001

dbSNP: rs5443
rs5443
0.010 GeneticVariation BEFREE C825T polymorphism in the G protein beta3 subunit gene (GNB3) has been associated with arterial hypertension, coronary artery disease and myocardial infarction. 10704626

2000

dbSNP: rs6020
rs6020
F5
0.020 GeneticVariation BEFREE Arg485Lys polymorphism of factor V increases the risk of coronary artery disease in a Chinese population. 11776127

2000

dbSNP: rs1799983
rs1799983
0.100 GeneticVariation BEFREE Glu298-->Asp polymorphism of the eNOS gene appears to be associated with the presence, extent, and severity of angiographically assessed coronary artery disease. 12010932

2002

dbSNP: rs16139
rs16139
0.050 GeneticVariation BEFREE Leucine 7 to proline 7 polymorphism in the preproneuropeptide Y is associated with proteinuria, coronary heart disease, and glycemic control in type 1 diabetic patients. 14747236

2004

dbSNP: rs1217691063
rs1217691063
0.100 GeneticVariation BEFREE C677T mutation of methylenetetrahydrofolate reductase gene and serum homocysteine levels in Turkish patients with coronary artery disease. 15648053

2006

dbSNP: rs1199475313
rs1199475313
0.010 GeneticVariation BEFREE T64A polymorphism in beta3-adrenergic receptor gene (ADRB3) and coronary heart disease: a case-cohort study and meta-analysis. 18088254

2008

dbSNP: rs7903146
rs7903146
0.020 GeneticVariation BEFREE rs7903146 T allele is associated with diabetes and, in non-diabetic individuals, with a higher prevalence and severity of coronary artery disease and cardiovascular events. name of registry site (see list below), registration number, trial registration URL in brackets. 19924244

2009

dbSNP: rs1799983
rs1799983
0.100 GeneticVariation BEFREE G894T polymorphism of eNOS gene was not associated with foot ulcer and diabetic complications, except in the presence of atherosclerotic heart disease. 20642368

2010

dbSNP: rs1799983
rs1799983
0.100 GeneticVariation BEFREE Glu298Asp polymorphism of the endothelial nitric oxide synthase (eNOS) gene (NOS3) has been characterized as a risk factor of hypertension and coronary artery disease. 21816783

2011

dbSNP: rs1049353
rs1049353
0.010 GeneticVariation BEFREE G1359A polymorphism in the cannabinoid receptor-1 gene is associated with the presence of coronary artery disease in patients with type 2 diabetes. 22138970

2012

dbSNP: rs2943634
rs2943634
0.010 GeneticVariation BEFREE rs2943634 C/A single nucleotide polymorphism (SNP), located in a non coding region of chromosome 2q36.3, has been associated with coronary artery disease in two genome wide association studies. 22207032

2012

dbSNP: rs1181860747
rs1181860747
0.010 GeneticVariation BEFREE Gly1057Asp polymorphism of insulin receptor substrate-2 is associated with coronary artery disease in the Taiwanese population. 23216712

2012

dbSNP: rs1805097
rs1805097
0.010 GeneticVariation BEFREE Gly1057Asp polymorphism of insulin receptor substrate-2 is associated with coronary artery disease in the Taiwanese population. 23216712

2012

dbSNP: rs25487
rs25487
0.010 GeneticVariation BEFREE Arg399Gln polymorphism of X-ray repair cross-complementing group 1 gene is associated with angiographically documented coronary artery disease in South Indian type 2 diabetic patients. 23360319

2013

dbSNP: rs20455
rs20455
0.090 GeneticVariation BEFREE Trp 719Arg have an effect on development of Coronary Heart Disease but it is very useful for statin therapy. 26443250

2015

dbSNP: rs72653706
rs72653706
0.050 GeneticVariation BEFREE A 16-year-old survivor of acute myocardial infarction with 3-vessel coronary artery disease exhibited compound heterozygosity for the well-known nonsense mutation (c.3421C>T; R1141X) in exon 24 and a novel missense mutation (c.3662G>A; R1221H) in exon 26 of the ABCC6 gene. 16854481

2007

dbSNP: rs63751001
rs63751001
0.010 GeneticVariation BEFREE A 16-year-old survivor of acute myocardial infarction with 3-vessel coronary artery disease exhibited compound heterozygosity for the well-known nonsense mutation (c.3421C>T; R1141X) in exon 24 and a novel missense mutation (c.3662G>A; R1221H) in exon 26 of the ABCC6 gene. 16854481

2007

dbSNP: rs6903956
rs6903956
0.030 GeneticVariation BEFREE A coronary artery disease-associated SNP rs6903956 contributed to asymptomatic hyperuricemia susceptibility in Han Chinese. 25928384

2015

dbSNP: rs974819
rs974819
0.010 GeneticVariation BEFREE A case-control study provides evidence of association for a common SNP rs974819 in PDGFD to coronary heart disease and suggests a sex-dependent effect. 22704460

2012