|
rs17321515
|
|
|
0.020 |
GeneticVariation |
BEFREE |
A polymorphism adjacent to the TRIB1 locus (rs17321515) was associated with elevated total cholesterol and LDL-cholesterol (LDL-C) after adjustment for age and sex (both P values <0.007) and with increased risk of coronary heart disease and CVD [odds ratio (OR) 1.23, 95% confidence interval (95% CI) 1.03-1.46; and OR 1.2, 95% CI 1.02-1.42, respectively] under an additive model of inheritance.
|
18987386 |
2009 |
|
rs17321515
|
|
|
0.020 |
GeneticVariation |
BEFREE |
TRIB1 rs17321515 gene polymorphism increases the risk of coronary heart disease in general population and non-alcoholic fatty liver disease patients in Chinese Han population.
|
31470861 |
2019 |
|
rs1746048
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Association between chemokine CXC ligand 12 gene polymorphism (rs1746048) and coronary heart disease: A MOOSE-compliant meta-analysis.
|
28614256 |
2017 |
|
rs1746048
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Relationship between chemokine (C-X-C motif) ligand 12 gene variant (rs1746048) and coronary heart disease: case-control study and meta-analysis.
|
23531450 |
2013 |
|
rs2107595
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Subgroup and multifactor dimensionality reduction analyses (MDR) further found the gene-environment interactions among SNP rs2107595, body mass index, type 2 diabetes and hyperlipidemia in CAD risk and the severity of coronary atherosclerosis.
|
27494404 |
2016 |
|
rs2107595
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Previous results suggest a role of altered <i>HDAC9</i> expression levels as the underlying disease mechanism. rs2107595, the lead single nucleotide polymorphism for stroke and coronary artery disease resides in noncoding DNA and colocalizes with histone modification marks suggestive of enhancer elements.
|
31500558 |
2019 |
|
rs501120
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Additionally, rs501120 (P = 8.36×10(-03), OR = 0.80) at 10q11.21 was associated with coronary atherosclerosis in females, but did not show association in males and all participants.
|
21698238 |
2011 |
|
rs501120
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Because previous genome-wide association studies demonstrated an association between CXCL12 rs501120 and coronary artery disease, in the present study we assessed the potential association of this polymorphism with the risk of cardiovascular (CV) disease in 1,321 Spanish patients with RA.
|
22386691 |
2012 |
|
rs10757283
|
|
|
0.010 |
GeneticVariation |
BEFREE |
For the first time to our knowledge, our results indicated that the same 9p21.3 locus, represented by SNPs rs10811661 and rs10757283, contributed to the risk of type 2 diabetes and coronary artery disease in our GeneID Chinese Han population.
|
21270277 |
2011 |
|
rs10811661
|
|
|
0.010 |
GeneticVariation |
BEFREE |
For the first time to our knowledge, our results indicated that the same 9p21.3 locus, represented by SNPs rs10811661 and rs10757283, contributed to the risk of type 2 diabetes and coronary artery disease in our GeneID Chinese Han population.
|
21270277 |
2011 |
|
rs10920501
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The relationships between FAM5C SNP (rs10920501) variability and metabolic syndrome and inflammation in women with coronary heart disease.
|
22013132 |
2013 |
|
rs12567209
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Adjustment for QT interval and coronary heart disease risk factors attenuated but did not eliminate the association between rs16847548 and SCD, and such adjustment had no effect on the association between rs12567209 and SCD.
|
19204306 |
2009 |
|
rs13144478
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In addition, the resistin-rising allele of the TYW3/CRYZ SNP rs3931020, but not the NDST4 SNP rs13144478, showed a consistent association with increased coronary heart disease risk [odds ratio = 1.18 (95% CI, 1.03-1.34); P = 0.01].
|
22843503 |
2012 |
|
rs139401390
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genome-wide association study suggests impact of chromosome 10 rs139401390 on kidney function in patients with coronary artery disease.
|
30809046 |
2019 |
|
rs16847548
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Adjustment for QT interval and coronary heart disease risk factors attenuated but did not eliminate the association between rs16847548 and SCD, and such adjustment had no effect on the association between rs12567209 and SCD.
|
19204306 |
2009 |
|
rs1870634
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association of the rs1870634 Variant in Long Intergenic Non-protein Coding RNA 841 with Coronary Artery Disease: A GWAS-Replication Study in an Iranian Population.
|
29654577 |
2018 |
|
rs2001844
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Bioinformatic analysis and resequencing identified a single SNP, rs2001844, within the promoter region that associates with increased plasma triglycerides and reduced high-density lipoprotein cholesterol and coronary artery disease risk.
|
24895164 |
2014 |
|
rs2431697
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two Single Nucleotide Polymorphisms (rs2431697 and rs2910164) of miR-146a Are Associated with Risk of Coronary Artery Disease.
|
28489066 |
2017 |
|
rs2870463
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two novel loci were associated with birthweight and adult coronary artery disease (rs2870463 in CTRB1) and with birthweight and adult waist circumference (rs12704673 in CALCR).
|
30858448 |
2019 |
|
rs2943634
|
|
|
0.010 |
GeneticVariation |
BEFREE |
rs2943634 C/A single nucleotide polymorphism (SNP), located in a non coding region of chromosome 2q36.3, has been associated with coronary artery disease in two genome wide association studies.
|
22207032 |
2012 |
|
rs383830
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Male-specific association of the APC rs383830 T allele with the risk of coronary heart disease.
|
26436499 |
2015 |
|
rs3869109
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results indicate that the rs3869109 variants are associated with premature coronary artery disease in a Chinese Han population, suggesting this genetic risk marker is useful in early coronary artery disease risk prediction.
|
23266671 |
2013 |
|
rs3931020
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In addition, the resistin-rising allele of the TYW3/CRYZ SNP rs3931020, but not the NDST4 SNP rs13144478, showed a consistent association with increased coronary heart disease risk [odds ratio = 1.18 (95% CI, 1.03-1.34); P = 0.01].
|
22843503 |
2012 |
|
rs7136716
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Subjects with homozygous minor alleles of the SNP rs7136716 had elevated microvessel density, increased expression of CD163 in ruptured coronary plaques, and a higher risk of myocardial infarction and coronary heart disease in population cohorts.
|
29457790 |
2018 |
|
rs7553007
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association of SNP rs7553007 in the CRP locus with coronary heart disease gave an odds ratio (OR) of 0.98 (95% CI, 0.94 to 1.01) per 20% lower CRP level.
|
19567438 |
2009 |