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rs10455872
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Topics enriched for CVD and hyperlipidemia had positive correlations with rs10455872 (P < 0.001), replicating a previous finding.
|
30759150 |
2019 |
|
rs1048943
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Hyperlipidemia could modulate the effect of CYP1A1 rs1048943 on the periodontal status of GAgP.
|
31032950 |
2019 |
|
rs2523608
|
|
|
0.010 |
GeneticVariation |
BEFREE |
After stratification, hyperlipidemia remained a risk factor in women (OR = 4.735, 95% CI: 3.375⁻6.643) and men (OR = 3.640, 95% CI: 2.916⁻4.544) with rs2523608 GG genotype.
|
30934611 |
2019 |
|
rs4713518
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our study indicates that hyperlipidemia-sex interactions exist for gout risk in Taiwanese adults with rs2523608 GG and rs4713518 AA genotypes.
|
30934611 |
2019 |
|
rs498005
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<b>Results:</b> C allele of rs498005 was significantly correlated with increased risk of AF (OR = 1.412, 95%CI = 1.012-1.970), and the association still exited after adjustment by age, gender, the status of smoking and drinking, histories of diabetes, hyperlipidaemia and myocardial infarction (adjusted OR = 1.473, 95%CI = 1.043-2.081).
|
31315459 |
2019 |
|
rs738409
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Accordingly, the naringenin-betaine cocrystals showed improved anti-hyperlipidemia effects on the C57 BL/6J PNPLA3 I148M transgenic mouse hyperlipidemia model.
|
30771018 |
2019 |
|
rs9349379
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Logistic regression analyses revealed that PHACTR1 rs9349379 GG genotype was significantly associated with increased risk of CAD in the recessive model (OR=2.359, 95% CI 1.442 to 3.862, p=0.001), even after adjusting for age gender, hypertension, type 2 diabetes, hyperlipidaemia and smoking habit.
|
30777881 |
2019 |
|
rs2066714
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We conducted a cross-sectional study to investigate the effects of the adenosine triphosphate-binding cassette transporter 1 (ABCA1) I883M and lipoprotein lipase (LPL) HindIII polymorphisms on lipid levels in patients with hyperlipidemia.A total of 533 patients were enrolled.
|
28891316 |
2018 |
|
rs2302685
|
|
|
0.010 |
GeneticVariation |
BEFREE |
It seems that LRP6 rs2302685 (V1062I) variant carriers are associated with an increased risk of hyperlipidemia in Iranian children and adolescents.
|
30039844 |
2018 |
|
rs662799
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Excess risk for low HDL-C and hyperlipidemia was associated with rs662799 genotype alleles of APOA5 SNPs in older Chinese adults.
|
29758349 |
2018 |
|
rs717620
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Female Chinese patients with hyperlipidemia carrying rs717620 GA/AA genotypes might have reduced benefit from simvastatin treatment.
|
30024814 |
2018 |
|
rs1042034
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The A allele of rs1042034 and the G allele of rs676210 may thus predispose middle-aged and elderly members of the Chinese Yugur population to HL in combination with other genetic or nutritional factors, and could be used as new genetic markers for HL screening.
|
28902930 |
2017 |
|
rs1137101
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Effects of LEP G2548A and LEPR Q223R Polymorphisms on Serum Lipids and Response to Simvastatin Treatment in Chinese Patients With Primary Hyperlipidemia.
|
26984935 |
2017 |
|
rs11615
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Multiplicative interactions among SNP rs11615, alcohol drinking, history of T2DM, and history of hyperlipidemia could increase 5.06-fold risk of CAD (P = 1.59 × 10<sup>-9</sup>).
|
28743890 |
2017 |
|
rs1256046734
|
|
|
0.010 |
GeneticVariation |
BEFREE |
LEPR Q223R polymorphism, but not LEP G2548A, could modulate the efficacy of simvastatin in Chinese patients with primary hyperlipidemia.
|
26984935 |
2017 |
|
rs13281615
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In premenopausal women, two environmental factors (history of breastfeeding, and history of benign breast disease) and four genetic variants (TOX3-rs3803662, ESR1-rs2046210, 8q24-rs13281615, and SLC4A7-rs4973768) were considered to be risk predictors, whereas three environmental factors (body mass index, history of breastfeeding, and hyperlipidemia), serum levels of testosterone and 25-hydroxyvitamin D, and two genetic variants (TOX3-rs3803662 and ESR1-rs2046210) were identified as risk predictors.
|
29029469 |
2017 |
|
rs2046210
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In premenopausal women, two environmental factors (history of breastfeeding, and history of benign breast disease) and four genetic variants (TOX3-rs3803662, ESR1-rs2046210, 8q24-rs13281615, and SLC4A7-rs4973768) were considered to be risk predictors, whereas three environmental factors (body mass index, history of breastfeeding, and hyperlipidemia), serum levels of testosterone and 25-hydroxyvitamin D, and two genetic variants (TOX3-rs3803662 and ESR1-rs2046210) were identified as risk predictors.
|
29029469 |
2017 |
|
rs3803662
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In premenopausal women, two environmental factors (history of breastfeeding, and history of benign breast disease) and four genetic variants (TOX3-rs3803662, ESR1-rs2046210, 8q24-rs13281615, and SLC4A7-rs4973768) were considered to be risk predictors, whereas three environmental factors (body mass index, history of breastfeeding, and hyperlipidemia), serum levels of testosterone and 25-hydroxyvitamin D, and two genetic variants (TOX3-rs3803662 and ESR1-rs2046210) were identified as risk predictors.
|
29029469 |
2017 |
|
rs4973768
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In premenopausal women, two environmental factors (history of breastfeeding, and history of benign breast disease) and four genetic variants (TOX3-rs3803662, ESR1-rs2046210, 8q24-rs13281615, and SLC4A7-rs4973768) were considered to be risk predictors, whereas three environmental factors (body mass index, history of breastfeeding, and hyperlipidemia), serum levels of testosterone and 25-hydroxyvitamin D, and two genetic variants (TOX3-rs3803662 and ESR1-rs2046210) were identified as risk predictors.
|
29029469 |
2017 |
|
rs676210
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The risk factors age (P=0.008), body mass index (P<0.0001), GA+GG genotype in rs676210 (P=0.009), and alcohol consumption (P=0.056) contributed strongly to HL development.
|
28902930 |
2017 |
|
rs679899
|
|
|
0.010 |
GeneticVariation |
BEFREE |
APOB polymorphisms were identified using mass spectrometry, and five single nucleotide polymorphisms (rs1042034, rs2163204, rs512535, rs676210, and rs679899) and serum lipids were further analyzed. rs1042034 and rs676210 were significantly associated with HL (P<0.05).
|
28902930 |
2017 |
|
rs8450
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Moreover, rs8450-AA genotype was associated with overweight or obesity (n=1215, OR=1.56, P=0.02), new-onset hyperlipidemia (n=1007, OR=1.76, P=0.007), and lower high-density lipoprotein-cholesterol (n=1214, β=-0.08, P=0.001).
|
26644205 |
2017 |
|
rs1941404
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The results show that a SNP (rs1941404) in <i>NNMT</i> is significantly associated with hyperlipidemia, and the influence of rs1941404 variation on the resting energy expenditure may be the possible mechanism for rs1941404 variation to induce hyperlipidemia.
|
27999813 |
2016 |
|
rs2071410
|
|
|
0.010 |
GeneticVariation |
BEFREE |
MATERIAL AND METHODS The odds ratios (ORs) and their 95% confidence intervals (95% CIs) were evaluated to assess the association of rs2071410 with TIA risk, and logistic regression was used to estimate the effects of various risk factors (e.g., diabetes, hypertension, and hyperlipidemia) on TIA.
|
27760099 |
2016 |
|
rs2107595
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Subgroup and multifactor dimensionality reduction analyses (MDR) further found the gene-environment interactions among SNP rs2107595, body mass index, type 2 diabetes and hyperlipidemia in CAD risk and the severity of coronary atherosclerosis.
|
27494404 |
2016 |